The invention discloses an efficient and low-toxicity herbicide used for a garden. The herbicide is prepared from the following raw materials in parts by weight: 1-2 parts of oxyfluorfen missible oil,14-18 parts of butachlor, 10-12 parts of acetochlor, 15-40 parts of triethanolamine, 4-8 parts of carfentrazone, 5-10 parts of clodinafop-propargyl, 10-20 parts of flumiclorac-pentyl missible oil, 12-15 parts of fomesafen, 8-15 parts of cloransulam-methyl, 5-10 parts of organosilicone, 20-35 parts of fenoxaprop-p-ethyl, 5-10 parts of glyphosate, 0.3-0.5 part of gibberellin, 0.1-0.2 part of indoleacetic acid, 10-12 parts of triacontanol, 2-4 parts of urea, 10-20 parts of carbetamide, 5-10 parts of clopyralid, 10-13 parts of mesotrione, 5-7 parts of bentazone, 6-8 parts of bensulfuron methyl, 10-12 parts of glufosinate-ammonium, 12-15 parts of glyphosate, 20-25 parts of water soluble salt and 100-150 parts of deionized water. All raw materials can be compounded to achieve purposes of complementing advantages, reducing a use amount, controlling effects and enhancing. The efficient and low-toxicity herbicide has the advantages of high effect taking speed, wide weed control spectrum, longlasting period, thorough weed removal, low residue, low toxicity, safety, environment protection and the like.