The invention discloses a white and interference-color matte flaky core-covered pigment and a preparation method thereof and relates to the field of pearlescent pigments. A base material with the grain diameter D50<=5 micrometers is coated with white metallic oxide to form a coating layer. According to the method, the base material and water are mixed to form suspension liquid, a crystal grain modifier is put in the suspension liquid, a metallic oxide crystal type transforming agent is added into the suspension liquid, the pH value is regulated, a saline solution is added dropwise into the suspension liquid, the pH value of the suspension liquid is kept stable at the same time, stirring is continued after adding is over, the pH value of the solution is regulated, an anti-aggregation agent is added, and suction filtration, drying, calcining and cooling are performed on the solution after adding is over. Compared with the prior art, the pigment prepared through the method is small in grain diameter, very fine and smooth, quite obvious in skin effect, high in covering force, good in ultraviolet absorption effect, low in luster, remarkable in matte effect and capable of being widely applied to cosmetics, sun cream, pigment toning and other industries.