The invention relates to a multi-knee-bending-angle knee joint finite element model and a preparation method thereof, and belongs to the field of joint anatomy. The model reversely reconstructs the main structure of the knee joint according to MRI data of healthy adults. The model collects and reconstructs a healthy knee joint three-dimensional model when actively bending the knee at 0 degree, 15 degrees, 30 degrees, 45 degrees, 60 degrees, 75 degrees, 90 degrees, 105 degrees and 120 degrees. The model comprises sixteen parts including a femur, a tibia, a fibula, a patella, a femur cartilage, a tibial plateau medial cartilage, a tibial plateau lateral cartilage, a patella cartilage, a medial meniscus, a lateral meniscus, an anterior cruciate ligament, a posterior cruciate ligament, a medial collateral ligament, a lateral collateral ligament, a quadriceps femoris tendon and a patellar tendon. The multi-knee-bending-angle knee joint finite element model is based on a real human knee joint, is complete in structure, is suitable for anatomical learning of the knee joint, and provides a unwonted real knee joint bending and stretching prediction model for simulating the actual condition of the knee joint, researching an injury mechanism, formulating a preoperative plan, clinical teaching and the like.