The invention discloses a circulating water breeding treatment system which comprises a fish tank fan, an oxygenerator, an ozone generator and an equipment fan. One side of the fish tank fan is communicated with a breeding tank through a pipeline, one side of the breeding tank is communicated with a rotational flow filter through a pipeline, one side of the rotational flow filter is communicated with a roller microfilter through a pipeline, and one side of the roller microfilter is communicated with a balance tank through a pipeline. Through matched using of an ultraviolet sterilizer, the rotational flow filter, a constant temperature machine, the oxygenerator, a dissolved oxygen cone, the roller microfilter, a dissolved oxygen pump, the balance tank, a degassing pump, a circulating pump,a protein separator, the ozone generator, the equipment fan, a biofilter and a degassing sterilization treater, the problem that existing circulating water breeding systems are inconvenient in breeding, wide in occupied area, troublesome in operation step, prone to being affected and constrained by natural environment like weather and water quality change and inconvenient for breeding management is solved.