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44results about How to "Guaranteed performance effect" patented technology

Universal construction method for protein-targeting chimeric molecule compound

The invention discloses a universal construction method for a protein-targeting chimeric molecule compound. The objective of the invention is to provide a method for adjusting the level of proteins by degrading the proteins through targeted ubiquitination. The construction method mainly comprises the following steps: 1) locating and analyzing a three-dimensional structure of a target protein and predicting active sites; 2) selecting a compound database; 3) virtually screening ligand compounds having high degrees of adaption to the target protein by using a computer; 4) acquiring the screened ligand compounds and screening an optimal ligand compound of the target protein through detection of interaction between micromolecules and the proteins; 5) constructing a protein-targeting chimeric molecule compound composed of the optimal ligand compound of the target protein, ubiquitin ligase E3 identification ligand and Linker connecting the optimal ligand compound of the target protein to the ubiquitin ligase E3 identification ligand by using a combination manner simulated by the computer; and 6) chemically synthesizing the protein-targeting chimeric molecule compound. With the method provided by the invention, the protein-targeting chimeric molecule compound can be rapidly and highly efficiently prepared, and specific degradation of intracellular target proteins is realized.
Owner:THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Micro flapping-wing analysis system and method involved with pneumatic and structural coupling properties

The invention provides a micro flapping-wing analysis system and method involved with pneumatic and structural coupling properties. The system comprises a main control computer, a server, a structural static property testing system, a structural dynamic property testing system, a pneumatic response analysis system, a structural response analysis system and a coupling response analysis system, all of which are connected to form a uniform integrated body through an optical fiber system. The main control computer is connected with the structural static and dynamic property testing systems and the server; the server is connected with the structural, pneumatic and coupling response analysis systems to control the three systems; professional analysis tools of the three response systems operate respectively, and finally, the analysis results are returned to the server while feedbacks are output. According to the invention, the difficulty of data exchange of the micro flapping-wing design and the comprehensive analysis of the pneumatic and structural coupling properties with two subjects is effectively overcome; the comprehensive analysis of complex problems involved with the pneumatic and structural subjects and automatic coordinated operation are realized; the design cycle of the micro flapping-wing is shortened; the design efficiency is improved.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Distributed power generation-based power coordinated control method of intelligent microgrid system

InactiveCN106936160AReduce the effect of output fluctuationReduce current abrupt changeSingle network parallel feeding arrangementsEnergy storageSmart microgridMathematical model
The invention discloses a distributed power generation-based power coordinated control method of an intelligent microgrid system. The power coordinated control method of the intelligent microgrid system comprises the following steps of 1, respectively building mathematical models of a wind power generation sub-system, a photovoltaic power generation sub-system and a storage battery energy storage sub-system according to a working principle of an intelligent microgrid; 2, designing an upper-layer distributed model forecast controller, wherein the wind power generation sub-system, the photovoltaic power generation sub-system and the storage battery energy storage sub-system are used for effectively and reasonably coordinating an output power by the upper-layer distributed model forecast controller, and the output power is transferred to a lower-layer sliding-mode variable structure sub-controller; 3, designing a first sliding-mode variable structure controller and a second sliding-mode variable structure controller; 4, designing a third sliding-mode variable structure controller and a fourth sliding-mode variable structure controller; and 5, switching control modes of the first sliding-mode variable structure controller, the second sliding-mode variable structure controller, the third sliding-mode variable structure controller and the fourth sliding-mode variable structure controller and controlling a storage battery switch.
Owner:NORTH CHINA ELECTRIC POWER UNIV (BAODING)

Rapid ventilation and smoke exhausting device and method for construction period of long-distance tunnel

The invention provides a rapid ventilation and smoke exhausting device for a construction period of a long-distance tunnel. The rapid ventilation and smoke exhausting device comprises a gantry bracket, a fixed wind door and a movable wind door, an axial flow ventilator and a jet flow draught fan, and a motor control system, wherein the fixed wind door is arranged at the upper end of the gantry bracket and the movable wind door is arranged on one side of the gantry bracket; the axial flow ventilator and the jet flow draught fan penetrate through the fixed wind door; the fixed wind door is matched with the unfolded movable wind door so that the axial wind flow in the tunnel is separated; a wind inlet of the axial flow ventilator and a wind outlet of the jet flow draught fan are formed in one side, which is close to a working surface, of the fixed wind door; the wind outlet of the axial flow ventilator is connected with a flexible wind barrel; the wind outlet of the flexible wind barrel extends to the outer part of the tunnel. According to a ventilation and smoke exhausting method provided by the invention, the wind doors for separating the axial wind flow are arranged in the tunnel; a safe space and a closed polluted space are formed on the two sides of the wind doors respectively, and pollutants in the polluted space can be discharged out of a hole along an airflow through a closed exhausting channel by using ventilation equipment; blasting equipment is used for blasting wind into the polluted space from the safe space so that the pollutants rapidly flows towards the inlet of the ventilation equipment.
Owner:中国葛洲坝集团第三工程有限公司

Liquid cross-linking agent injecting device

The invention relates to a liquid cross-linking agent injecting device, which comprises a liquid storage tank, wherein the top of the liquid storage tank is provided with a cross-linking agent inlet; the cross-linking agent inlet is connected with a self suction pump through a pipeline; the bottom of the liquid storage tank is provided with a cross-linking agent outlet; the cross-linking agent outlet is connected with a cross-linking agent injecting pump through a pipeline; an exhaust valve is arranged on the cross-linking agent injecting pump; a pressure transmitter and an electromagnetic flow meter are arranged on a pipeline arranged at the outlet end of the cross-linking agent injecting pump; and the liquid cross-linking agent injecting device also comprises a control device. The liquid cross-linking agent injecting device has the advantages that the process preparation high-quality injection can be realized; a uniform and stable cross-linking solution system is formed; the metering precision of cross-linking agent adding is improved; the injecting quality and the action effect of the liquid cross-linking agents are ensured; meanwhile, the liquid cross-linking agent injecting device adopts a skid-mounted design, thereby being compact in structure, convenient to carry and low in equipment investment cost.
Owner:PETROCHINA CO LTD

High-effective fertilizer for strawberries with addition of active functional bacteria carbon aerogel and preparation method thereof

The invention belongs to the field of fruit fertilizers and particularly discloses a high-effective fertilizer for strawberries with addition of active functional bacteria carbon aerogel. The fertilizer includes, by weight, stevioside, bacterial cellulose, polyvinylpyrrolidone, triacontanol, active functional bacteria, gibberellins, auxin, soybean phospholipid, nano diatomite micro-powder, tithonia diversifolia powder, rapeseed oil residue, sweet potato leaf powder, EM bacteria, EDTA chelated manganese, borax, brassinolide, fulvic acid, glycine, nicotinic acid, and activated diatomite, etc. The fertilizer is prepared from a main material by fermenting the tithonia diversifolia powder, the rapeseed oil residue, the sweet potato leaf powder and the like by means of the EM bacteria, so that abundant organic and mineral nutrients are supplied. By addition of the stable active functional bacteria carbon aerogel, during growth and development of the strawberries, the active functional bacteria improve decomposition and utilization of related nutrients, and meanwhile, through further enrichment, absorption and utilization, efficiency of the fertilizer is improved. The fertilizer, by synergistic effects of the components, can improve cultivation efficiency of the strawberries.
Owner:HEXIAN CHANGJIU AGRI DEV

Glass bottle mould

The invention discloses a glass bottle mould, and relates to the technical field of moulds. The glass bottle mould comprises a forming mould, a mouth mould, a bottom mould and a blow head, wherein the forming mould is made from a cast iron material, a first blocking groove is formed in the forming mould, and a first excitation coil is arranged in the first blocking groove; a forming cavity is formed between the forming mould and the bottom mould; a plurality of steel balls are arranged in the forming cavity; the glass bottle mould also comprises a ball suction iron rod; a second blocking groove is formed in the ball suction iron rod, a second excitation coil is arranged in the second blocking groove, the ball suction iron rod can extend into the forming cavity, a vent hole is formed in the ball suction iron rod, and a plurality of exhaust holes communicated with the vent hole are also formed in the part, extending into the forming cavity, of the ball suction iron rod. When the glass bottle mould adopting the scheme is used for producing glass bottles, the heat in the glass bottles also can be effectively dissipated in time, so that the problem that the glass bottles have cracks or are broken since stress, caused by not timely cooling of the interiors of the glass bottles during glass bottle production, is easily generated in the glass bottles can be avoided.
Owner:CHONGQING SANXING JINGYI GLASS CO LTD

Control system and method for automatically adjusting refrigerant of air-cooled compression condensing unit

InactiveCN110986261AGuarantee refrigerant consistency and performance capability and reliabilityPromote a wide range of applicationsMechanical apparatusSpace heating and ventilation safety systemsSubcoolingRefrigerant
The invention belongs to the technical field of air conditioner control, and discloses a control system and method for automatically adjusting a refrigerant of an air-cooled compression condensing unit. According to the control method, a refrigerant pipe is additionally arranged on a system pipe on an air suction pipe or a large valve connecting pipe of an air-conditioning system, an electromagnetic valve is used for stopping the middle of an additionally-arranged fluorine adding pipe, and a fluorine injection nozzle is additionally arranged at the end of the fluorine adding pipe and installedon an air-conditioning outdoor unit; an electromagnetic valve is opened for starting a refrigerant filling mode, and the refrigerant is filled from the fluorine filling nozzle; liquid outlet temperature and pressure detection is added to a condensation outlet pipe of the air conditioning system and used for controlling and detecting the supercooling degree of the refrigerant amount of the system.According to the control system and method, the perfusion amount and the use performance capability of a unit system can be kept consistent in a user installation site and a site test, the system operation reliability is not influenced by human factors, the popularization and application range is wide, and the effect is remarkable.
Owner:GREE ELECTRIC APPLIANCES INC OF ZHUHAI

Preparation process of Eddy injection preparation

The invention relates to the field of medicine, in particular to a preparation process of an Eddy injection preparation. The preparation process of the Eddy injection preparation comprises the following steps: taking Chinese blister beetle, ginseng, astragalus membranaceus and acanthopanax as raw materials, performing warm dipping on the ginseng and performing alcohol extraction, jointly decoctingthe ginseng residues, the astragalus membranaceus and the acanthopanax and performing aqueous extraction, combining extraction liquid, performing alcohol and water precipitation alternately for manytimes and performing refrigeration treatment so as to completely precipitate and remove the impurities, greatly reduce the impurities in the medicine liquid and reduce the occurrence rate of adverse reaction, adjusting the pH, performing ultrafiltration and performing refrigeration for later use; performing warm dipping on the Chinese blister beetle and performing aqueous extraction, performing treatment by a lime surface method, performing alcohol precipitation for twice, refrigerating, filtering, performing water precipitation for twice, adjusting the pH, refrigerating and performing ultrafiltration; and mixing the Chinese blister beetle extracting liquid, the extracting liquid of the ginseng, the astragalus membranaceus and the acanthopanax, adding auxiliary materials and adjusting thepH. The preparation process of the Eddy injection preparation has the advantages of high extraction efficiency, high purity and low occurrence rate of adverse reaction.
Owner:GUIZHOU YIBAI PHARMA CO LTD

A continuous reinforcement learning system and method based on stochastic differential equations

The invention discloses a continuous reinforcement learning system and method based on stochastic differential equations. The system includes an action policy generator APG, an environment state estimator ESE, a value estimator VE, a memory storage module MS and an external environment EE; the specific steps are as follows : Initialize the action policy generator APG, the environment state estimator ESE and the value estimator VE; the action policy generator APG calculates the output action value increment Δa k ;The external environment EE outputs the next action value a k+1 , next step environment state value s k+1 and the current step reward value R k , and stored in the memory storage module MS; the environmental state estimator ESE updates the environmental state parameter set θ p and predicted future environmental state estimates s′ k ; The VE optimizer updates the Q-function network and predicts the future reward estimate R′ k ; The APG optimizer updates the action value parameter set θ v . This method is based on stochastic differential equations as the basic model, which can realize the continuity of action control and control the variance of the training process, and can select actions by predicting changes in the environment to achieve better environmental interaction.
Owner:SHANGHAI UNIV

Efficient muskmelon fertilizer with plant active extract carbon aerogel added and preparation method

The invention belongs to the field of fruit fertilizer and particularly discloses efficient muskmelon fertilizer with plant active extract carbon aerogel added. The fertilizer is characterized by being prepared from components in parts by weight as follows: carboxymethyl chitosan, N-methyl pyrrolidone, polyvinyl alcohol, pear essence, nano silver ions, a brick tea extract solution, soluble chitosan, nano zeolite powder, silkworm excrement, composted traditional Chinese medicine residues, bryophyte, active selenium-enriched yeast powder, amino acid, polylactic acid, nano kaolin and the like. The silkworm excrement, the composted traditional Chinese medicine residues and the bryophyte are fermented, the muskmelon fertilizer is prepared, the nutrition is rich, dewatering can be realized, the humidity of soil can be regulated, the traditional Chinese medicine residues are fermented to provide growth-promoting efficient nutrient substances convenient to absorb and utilize for muskmelons, meanwhile, the stable plant active extract carbon aerogel is added to the fertilizer, the activity of the plant active extract is guaranteed, the slow-release time is prolonged, the absorbing and utilizing efficiency of the fertilizer is also improved, the flavor of the muskmelons is enriched jointly, and efficient cultivation of the muskmelons is promoted.
Owner:MAANSHAN KEBANG ECO FERTILIZER

A sprayer and its maintenance method

The invention provides a sprayer and a maintenance method thereof, comprising a housing, an installation port and a spout are arranged on the housing, an ampoule is installed at the installation port, a liquid inlet needle and a spray assembly are also included, and a liquid inlet needle is provided on the liquid inlet needle. channel and vent channel, the liquid inlet puncture needle punctures the ampoule so that one end of the liquid inlet channel is located in the ampoule, the other end of the liquid inlet channel is connected to the spray assembly, the spray assembly includes a valve seat, an atomizing air pump, and the valve seat is provided with The liquid inlet, air inlet and spray port, the atomizing air pump is connected to the air inlet, the liquid inlet channel is connected to the liquid inlet through the liquid inlet pipe, the spray port is located at the spray port, and the valve core moves at the spray port to control the spray port Open and close, control the start switch to make the sprayer work, use the method of piercing the ampoule with a liquid-feeding needle, and draw out the cosmetic or pharmaceutical liquid from the ampoule to take it, avoiding a large area of ​​the liquid in the ampoule directly contacting the air, It also avoids direct contact of human hands with the liquid in the ampoule, effectively reducing the pollution to the liquid in the ampoule.
Owner:YANGSHENGTANG (ANJI) COSMETICS CO LTD

Sprayer and maintenance method thereof

The invention provides a sprayer and a maintenance method thereof.The sprayer comprises a shell; the shell is provided with a mounting opening and a nozzle; an ampoule is arranged at the mounting opening; the sprayer further comprises a liquid inlet puncturing needle and a spraying assembly; the liquid inlet puncturing needle is provided with a liquid inlet channel and a ventilation channel; the liquid inlet puncturing needle punctures the ampoule so that one end of the liquid inlet channel can be located in the ampoule; the other end of the liquid inlet channel is connected to the spraying assembly; the spraying assembly comprises a valve seat and an atomizing air pump; the valve seat is provided with a liquid inlet, an air inlet and a spraying opening; the atomizing air pump is connectedto the air inlet; the liquid inlet channel is connected to the liquid inlet through a liquid inlet pipe; the spraying opening is located at the nozzle; and a valve element moves at the spraying opening so as to control the spraying opening to be opened and closed. A starting switch is controlled to enable the sprayer to work, cosmetic or medicament liquid is taken out from the ampoule in a quantitative mode in the mode that the liquid inlet puncturing needle punctures the ampoule, the liquid in the ampoule is prevented from making direct contact with air in a large area, a person is preventedfrom making direct contact with the liquid in the ampoule with hands, and pollution to the liquid in the ampoule is effectively reduced.
Owner:YANGSHENGTANG (ANJI) COSMETICS CO LTD

Formalin solution mixing preparation device

The invention discloses a formalin solution mixing preparation device and relates to the technical field of medical equipment. Supporting legs are fixedly connected to two sides of the bottom of a supporting plate; a fixing plate is fixedly connected to a center shaft of the top of the supporting plate; a liquid storage tank is fixedly connected to the left side on the top of the supporting plate;a micro water pump is fixedly connected to the top of the liquid storage tank; a water outlet of the micro water pump is communicated with a first guide pipe; a flow divider is fixedly connected to the upper part of the front surface of the fixing plate; one end, which is far away from the micro water pump, of the first guide pipe is communicated with the flow divider; a hard guide pipe is communicated with the bottom of the flow divider; the bottom of the hard guide pipe runs through to the bottom of the supporting plate and is fixedly connected with a soft guide pipe; and a mixing tank is arranged below the supporting plate. According to the device disclosed by the invention, the formalin solution can be accurately and effectively proportioned, the concentration of the formalin is ensured to be in a target concentration range, and the drug property and action effect of the formalin are further effectively ensured.
Owner:李亚琴

A glass bottle mold

The invention discloses a glass bottle mould, and relates to the technical field of moulds. The glass bottle mould comprises a forming mould, a mouth mould, a bottom mould and a blow head, wherein the forming mould is made from a cast iron material, a first blocking groove is formed in the forming mould, and a first excitation coil is arranged in the first blocking groove; a forming cavity is formed between the forming mould and the bottom mould; a plurality of steel balls are arranged in the forming cavity; the glass bottle mould also comprises a ball suction iron rod; a second blocking groove is formed in the ball suction iron rod, a second excitation coil is arranged in the second blocking groove, the ball suction iron rod can extend into the forming cavity, a vent hole is formed in the ball suction iron rod, and a plurality of exhaust holes communicated with the vent hole are also formed in the part, extending into the forming cavity, of the ball suction iron rod. When the glass bottle mould adopting the scheme is used for producing glass bottles, the heat in the glass bottles also can be effectively dissipated in time, so that the problem that the glass bottles have cracks or are broken since stress, caused by not timely cooling of the interiors of the glass bottles during glass bottle production, is easily generated in the glass bottles can be avoided.
Owner:CHONGQING SANXING JINGYI GLASS CO LTD
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