The invention relates to a processing technology for dextran-MLDH-fluorouracil super-molecular skeleton magnetic liposome. The magnetic liposome takes dextran-MLDH-fluorouracil DMF three-grade super-molecular as the core skeleton, soya lecithin and cholesterol as the lipid raw materials, and is prepared by the reverse evaporating method. The DMF magnetic liposome has a typical in-vitro control release ability, a sensitive magnetic responding ability, an excellent cancer cell proliferation inhibiting ability and a special and durable in-vitro drug process. DMF magnetic liposome is prepared through combination of convention liposome technology and DMF, a novel inorganic nano drug delivery system, and a new approach is provided for magnetic target chemotherapy of fluorouracil, a wide-spectrum anti-cancer drug. The dextran-MLDH-fluorouracil super-molecular skeleton magnetic liposome is suitable for the preparation of magnetic drug liposome, which takes magnetic layered composite hydroxide MLDH as the carrier, has the processing advantages of low cost and simple preparation, and has the characteristics of integration of magnetic-target and control-release functions, durable effect, stable curative effect, and little toxic and side effects.