The invention discloses a water quality detection device capable of detecting water sources at different depths, comprising a water quality detection device main body, a protective casing, a water quality detector, a first protective cover, a floating bag and a sealing plate. There is a lift bin, and the top of the lift bin is connected to the storage bin, the protective shell is located at the lower end of the lift bin, and the lower end of the lift bin is connected to the water pump through a water pipe, and the first protective cover is provided by a rotating hinge and a buckle Filter holes are arranged on the lower end of the protective shell, and both the first protective cover and the second protective cover, the floating bag is arranged on the ruler rope, and the lower end of the ruler rope is arranged inside the storage bin, and the sealing plate passes through The rotating hinge and the buckle are arranged above the storage compartment. The water quality detection device capable of detecting water sources at different depths is provided with a lifting bin on the water quality detection device main body, which is beneficial to the water quality detection device main body to detect water quality at different depths in the water area.