The invention discloses a motor cooling device for biotechnological production, which comprises a cooling box, a box door is hinged to the cooling box, a supporting plate is fixedly connected to the inner bottom of the cooling box, a sliding groove is formed in the supporting plate, a supporting column is slidably connected into the sliding groove, and a servo motor is mounted on the inner wall ofthe cooling box. And the output end of the servo motor is fixedly connected with an adjusting screw rod, the adjusting screw rod extends into the sliding groove, the adjusting screw rod penetrates through the supporting column and is in threaded connection with the supporting column, the upper end of the supporting column is fixedly connected with a net plate, and a motor body is arranged on thenet plate. The equipment is reasonable in structure, work of the water pump and the semiconductor chilling plate can be automatically controlled according to actual requirements, through cooperation of air cooling and water cooling, the motor can be effectively and efficiently cooled, protection of the motor is achieved, meanwhile, electric resources can be saved, meanwhile, the motor can be conveniently taken and placed, and convenience is brought to workers.