The invention discloses a ball valve sealing test machine and aims to provide the ball valve sealing test machine which is convenient to operate, has high-accuracy test result and can guarantee that two pipe ends of a ball valve are prevented from being damaged by clamping. The ball valve sealing test machine comprises an air feeding pump, an air pressure sensor, a main frame, two push cylinders, two side frames, a main end cover and a secondary end cover, wherein the two push cylinders are respectively arranged on the side frames, a piston rod of one push cylinder is connected with the main end cover, a piston rod of the other push cylinder is connected with the secondary end cover, the main end cover is provided with a main elastic sealing ring pad, the secondary end cover is provided with a secondary elastic sealing ring board, and the main end cover is provided with a main cover air hole. The ball valve sealing test machine is advantaged in that, sealing and avoidance of damage to the ball valve can be guaranteed through positioning and clamping the ball valve in position, an adaptively-adjustable sealing structure is realized, the sealing effect during high-pressure detection can be strengthened, the ball valve sealing test machine has an auxiliary positioning structure, the end cover can be prevented from backspacing, the push cylinders are protected, the sealing effect is improved, and stability of the detection process is maintained.