Enteral nutrition preparation for dialysis patients and preparation method thereof

An enteral nutrition preparation and patient technology, applied in food preparation, application, food science, etc., can solve problems such as no enteral nutrition preparation for dialysis patients, achieve prevention of complications, broad application prospects, and improve quality of life Effect

Active Publication Date: 2016-04-27
HUAREN PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In the patent literature, there are currently health food or special diets for patients with kidney disease, such as "Patent No. 201110136080.X "Special Homogenized Meal for Kidney Disease"; "Dietary Food Formula"" are nutrition prescriptions for patients with kidney disease, and there is no enteral nutrition preparation specifically for dialysis patients

Method used

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  • Enteral nutrition preparation for dialysis patients and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Sea cucumber peptide refers to the hydrolysis and refining of fresh sea cucumber by protease. The specific preparation process includes the following steps:

[0038](1) Raw material pretreatment: fresh or dried sea cucumbers are thoroughly removed from the cavity, rinsed with seawater for 3 times, cut into 2cm / pieces for later use;

[0039] (2) Desalination: add pure water 15 times the volume of the sea cucumber into the container, soak it at -2°C for 12 to 24 hours, then remove the water, and repeat this process 3 times;

[0040] (3) Refining: add 3 times of water to crush and refine;

[0041] (4) Enzymolysis: Add neutral protease to the sea cucumber slurry at a temperature of 55°C and a pH value of 7.5, stir at a constant temperature, keep it for 2 hours, and filter through a membrane after coarse filtration;

[0042] (5) Enzyme inactivation: Mix sea cucumber enzymatic hydrolysis solution and heat to 80°C, keep it for 30 minutes, then cool down to 25°C;

[0043] (6)...

Embodiment 2

[0046] Hijiki polysaccharide refers to refined from Hijiki through hot water extraction process. The specific preparation process includes the following steps:

[0047] (1) Raw material pretreatment: take hijiki, wash with water to remove sundries, dry at 50°C, and pulverize. The obtained hijiki powder can pass through a 20-mesh sieve.

[0048] (2) Preparation of crude polysaccharide: add 2~3 volumes of distilled water, adjust the pH to 4, extract in a water bath at 60°C for 12 hours, extract 5 times, concentrate the extract to 1 / 3 volume, add 3 volumes of absolute ethanol, and heat at 8°C Let it stand for 24 hours, then centrifuge, collect the precipitate, and freeze-dry to obtain the crude hijiki polysaccharide.

[0049] (3) Deproteinization: Add 10 mg of the above-mentioned crude polysaccharide from Hijiki to 1 ml of distilled water, stir evenly, and prepare 1 mg / mL trypsin solution at the same time, then mix the trypsin solution and the crude polysaccharide solution from ...

Embodiment 3

[0054] An enteral nutrition preparation for dialysis patients, the enteral nutrition preparation per 100ml contains the following ingredients:

[0055] (1) Raw material mixing: Weigh 1.6g of sea cucumber peptide prepared in Example 1; 0.7g of soybean protein peptide; 0.7g of whey protein peptide; 9.5g of maltodextrin, 1.6g of fructose; hijiki polysaccharide prepared in Example 2 1.6g; 0.7g of linseed oil, 0.7g of fish oil, 1.4g of medium chain triglycerides; 1.0g of fructo-oligosaccharides; 1.0g of lacto-oligosaccharides, 100mg of sodium; 150mg of potassium; 150mg of chlorine; 100mg of calcium; Phosphorus 50mg; Magnesium 25mg; Iron 1.7mg; Zinc 1.5mg; Manganese 0.3mg; Copper 0.2mg; Iodine 13μg; Selenium 7.0μg; Chromium 7.0μg; Molybdenum 7.0μg; 3 0.60μg; Vitamin E1.0mg; Vitamin K55μg; Vitamin B 1 0.1 mg; Vitamin B 2 0.2 mg; Vitamin B 6 0.2 mg; Vitamin B 12 0.3μg; vitamin C4.0mg; niacin 1.5mg; folic acid 20μg; pantothenic acid 0.7mg; biotin 8μg; choline 40mg.

[0056] Under ...

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Abstract

The present invention relates to a nutrition preparation for dialysis patients and the preparation comprises the following ingredients: sea cucumber polypeptides, soy protein peptides, whey protein peptides, maltodextrin, fructose, sargassum fusiforme polysaccharides, linseed oil, fish oil, medium chain triglycerides, fructooligosaccharides, oligosaccharides, sodium, potassium, chlorine, calcium, phosphorus, magnesium, iron, zinc, manganese, copper, iodine, selenium, chromium, molybdenum, fluorine, vitamin A, vitamin D3, vitamin E, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, niacin, folic acid, pantothenic acid, biotin and choline. The nutrition preparation method aims at the nutritional and metabolic needs of dialysis patients, uses a reasonable compounding of the sea cucumber polypeptides with a unique pharmacological bioactivity and the sargassum fusiforme polysaccharides, develops a personalized enteral nutrition preparation for dialysis patients, provides balanced nutrition for dialysis patients, and effectively prevents the occurrence of complications.

Description

technical field [0001] The invention relates to the field of enteral nutrition preparations, in particular to an enteral nutrition preparation for dialysis patients and a preparation method thereof. Background technique [0002] Since the 1970s, due to the progress of metabolic theory, nutritional drugs and drug delivery methods, nutritional support has been widely used clinically and achieved satisfactory results. Nutritional support can mainly improve the nutritional status of patients, that is, to maintain nitrogen balance, reduce the consumption of lean body tissue, and maintain the protein quality of the body. But from the perspective of clinical treatment, the more important role of nutritional support is to maintain the metabolism of cells, organs and tissues so that they can perform normal functions, participate in the regulation of the body's immune function and physiological functions, accelerate tissue repair and promote patient recover. Nutritional support is c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/305A23L1/304A23L1/303
Inventor 韩瑶
Owner HUAREN PHARMACEUTICAL CO LTD
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