Methods and related systems are described for detection of
breast cancer in 3D
ultrasound imaging data. Volumetric
ultrasound images are obtained by an automated
breast ultrasound scanning (ABUS) device. In ABUS images breast cancers appear as dark lesions. When viewed in transversal and sagittal planes, lesions and
normal tissue appear similar as in traditional 2D
ultrasound. However, architectural
distortion and spiculation are frequently seen in the coronal views, and these are strong indicators of the presence of
cancer. The described computerized detection (CAD)
system combines a dark
lesion detector operating in 3D with a
detector for spiculation and architectural
distortion operating on 2D coronal slices. In this way a sensitive detection method is obtained. Techniques are also described for correlating regions of interest in ultrasound images from different scans such in different scans of the same breast, scans of a patient's right versus
left breast, and scans taken at different times. Techniques are also described for correlating regions of interest in ultrasound images and
mammography images. Interactive user interfaces are also described for displaying CAD results and for displaying corresponding locations on different images.