A method of implanting a wireless device within a patient is provided. The wireless device is capable of wirelessly communicating within another device (e.g., an external device) using, e.g., acoustic energy, electromagnetic energy, or magnetic energy. The method comprises forming a surgical opening within the patient to expose an anatomical structure, and repairing or replacing the anatomical structure. The method further comprises introducing the wireless device into an anatomical cavity (e.g., a blood vessel or a heart chamber) via the surgical opening. The method further comprises affixing the wireless device within the anatomical cavity (e.g., using the securing means set forth above), wherein the entire device is contained within the anatomical cavity.