The invention discloses a safety and stability analysis method and system based on a man-machine hybrid power system. The method comprises the steps that in a man-machine mode, according to a general knowledge base, a training execution agent and an interaction agent, and according to the execution agent and the interaction agent, a special knowledge base is determined, and the man-machine mode is a human dominant-machine following mode; and in a robot mode, according to the special knowledge base, executing a power system task, the robot mode being a mode of robot independence-human supervision. Therefore, a man-machine hybrid power system task execution method is formed, the AI interpretability level and the AI credibility are improved, multi-dimensional cognition of complex power grid operation characteristics is achieved, the safety and stability level of a power system is improved, and the workload of people in actual production is reduced.