The invention discloses a composition for treating inflammatory bowel disease, and belongs to the field of drugs. The composition comprises ganoderma, poria cocos, glutamine, threonine, serine, cysteine, vitamin C, vitamin E, vitamin A and beta-carotene, wherein ganoderma and poria cocos have efficacies of strengthening blood supply and oxygen supply to the human body; glutamine is a main energy source of intestinal mucosa; threonine, serine and cysteine are components of mucoprotein; vitamin C, vitamin E, vitamin A and beta-carotene have functions of inhibiting the activity of oxygen free radicals, scavenging the oxygen free radicals, and protecting human cells. The composition provides nutrition, oxygen and raw materials for generation, renewal and repairing of goblet cells as well as forming of an intestinal surface mucous layer barrier by utilizing mucoprotein secreted by the goblet cells, has obvious effects of eliminating inflammation, repairing intestinal tissues and building the normal intestinal surface mucous layer barrier for the human body, and is used for effectively treating the inflammatory bowel disease.