81 results about "Lymphatic oedema" patented technology

The invention relates to the technical field of medical data management and analysis, in particular to a lymphedema treatment monitoring data management method and system. Comprising the following steps: synchronously acquiring bioelectrical impedance, tissue thermodynamic characteristics and subcutaneous tissue morphological data of a patient through multi-modal data acquisition equipment; transmitting the data to a cloud processing platform in a distributed manner, and generating a three-dimensional illness state assessment map containing edema quantitative indexes through a machine learning assessment model; generating a personalized treatment strategy adjustment scheme with a confidence score based on dynamic comparison between the current evaluation map and historical data; feeding back the evaluation map and the adjustment scheme to the medical staff through the interaction terminal, and receiving a clinical correction instruction; according to the method, on the premise of strictly protecting patient data privacy, cross-mechanism multi-modal knowledge sharing can be realized, and the contradiction between a data island and a model effect is solved.

The invention discloses a universal lymphedema measuring scale for upper and lower limbs, relates to the technical field of medical measuring instruments, and provides the following scheme: the universal lymphedema measuring scale comprises a pedal plate for a detector to step on and fix; the leg detection mechanism is arranged at the top of the pedal plate and used for detecting lymphedema of the lower limbs of a detector, and the leg detection mechanism comprises a height measuring rod; the balance plate is fixed at the top of the height measuring rod; and the arm detection mechanism is arranged on the balance plate and is used for performing upper limb lymphedema detection on the detected person. The device can accurately measure the lymphedema degree of the upper and lower limbs, has the advantages of simplicity and convenience in operation, reliable measurement result, high practicability and the like, can be widely applied to the medical field, and solves the problems of non-uniform measurement, high randomness, nonstandard operation and the like in an existing measurement mode; and a reliable measuring tool is provided for diagnosis and treatment effect evaluation of lymphedema.

A limb circumference detection device includes a wire-pulling module, a first measurement module, and a second measurement module. The wire-pulling module is disposed around the limb in a surrounding manner. The first measurement module is arranged on the wire-pulling module, and the second measurement module is connected to the wire-pulling module. The first measurement module moves along the long axis direction of the limb and simultaneously measures the length of the limb. When the second measurement module moves along the long axis direction of the limb, the first measurement module synchronously measures the length of the wire-pulling module surrounding the limb, thereby continuously detecting the correlation between the limb length and the circumference. Two sets or even more than two sets of the wire-pulling modules of the detection device can be used in parallel. When two sets of wire-pulling modules are used in parallel, they can be used to monitor the change in limb softness, that is, compliance. When multiple sets of wire-pulling modules are used in parallel, they can be used for the treatment of limb edema.

Processing generated sensor data of a lymphedema device may include identifying use of the lymphedema device corresponding to a user. Sensor data associated with the user's identified use of the lymphedema device may be generated. At least some of the generated sensor data may comprise use data associated with a duration of use of the lymphedema device by the user. A protocol associated with use of the lymphedema device may be processed. The generated use data and the protocol associated with use of the lymphedema device may be correlated. Based on correlating the generated use data and the protocol, an alert associated with the generated use data and the protocol may be generated.

This invention relates to a method for calculating and correcting the volume of a limb with lymphedema. The method involves acquiring the outer contour data of the limb with lymphedema under a first and second standard measurement position, and dividing the limb into segments along its length with equal intervals to obtain two sets of corresponding volume segments. The volume of each corresponding segment is calculated, and the volume difference for the same segment number is determined. The volume segment whose absolute value of the volume difference is greater than a preset threshold is identified as the target volume segment. Based on the correspondence of the local volume distribution of the target volume segment in the two sets of volume segments, the volume difference is determined to be either a solid increment or a positional drift increment. Using the volume of each volume segment under the first standard measurement position as a benchmark, the solid increment is retained in the target volume segment, and the positional drift increment is corrected. The volumes of each volume segment after correction are summed to obtain the corrected volume of the limb with lymphedema.

1. Name of the designed product: skin pad (lymphedema). 2. Use of the designed product: skin pad for lymphedema. 3. Design points of the designed product: in shape. 4. Picture or photo best indicating the design points: perspective view.

1. Name of the designed product: measuring instrument (lymphedema). 2. Use of the designed product: for measuring lymphedema. 3. Design points of the designed product: in shape. 4. Picture or photo best indicating the design points: perspective view.

The utility model provides a scrotum support for a detumescence lymphatic pad of a male lymphedema patient, which relates to the technical field of medical tools and comprises a waistband, connecting bands and a support body, the connecting bands are connected to two sides of the front end of the waistband, and the support body is connected below the connecting bands; the support body is in a concave shape and comprises outer screen cloth and a lymph drainage pad, the lymph drainage pad is arranged on the inner side of the outer screen cloth, multiple sets of protruding particles are arranged and distributed on the inner side of the lymph drainage pad, and an adjusting piece is arranged on the outer side of the outer screen cloth; the waist support is tied on the waist through the waistband and connected with the support body through the connecting belt for limiting, the support body is prevented from falling off, the support body acts on the hypogastrium and scrotum lymphedema area of a male patient, and through the concave lymphatic drainage pad and the convex particles distributed in an arrayed mode, lymphatic backflow is promoted, and the problem of lymphadema fibrosis is solved. The product adapts to the structure requirement of male external genitalia, and the treatment quality is improved.

The invention discloses an electrical stimulation lymphedema rehabilitation device, and relates to the technical field of lymphedema rehabilitation, and the device comprises a housing, and also comprises an electrical stimulation mechanism which is installed at the top of the housing and comprises a plurality of electrode plates; the limb supporting mechanism is installed on the two sides of the shell and comprises a first lantern ring and a second lantern ring; the multi-section massage mechanism is installed in the shell and comprises a plurality of air bags, and one side of each air bag is communicated with an electromagnetic valve; the uniform pressing mechanism is connected with the multi-section massage mechanism and comprises a downward moving anti-sticking mechanism and a translation switching mechanism; the electrical stimulation mechanism further comprises a controller fixed to the top of the shell, and the controller is electrically connected with the multiple electrode slices. By installing the uniform pressing mechanism, uniform massage is achieved, the pressing position of the air bag is changed, the whole limb is pressed uniformly, the pressing strength of all parts of the limb is prevented from being different, the problem that the whole limb is pressed unevenly is effectively solved, and therefore lymph circulation is more efficiently promoted.

The invention relates to the technical field of medical instruments, and provides a lymphedema therapeutic apparatus with a self-cleaning device and a cleaning method.The lymphedema therapeutic apparatus comprises a therapeutic apparatus body, a cleaning device body is movably arranged in the therapeutic apparatus body, a vibration device is fixedly arranged in the therapeutic apparatus body, and a sweeping device and a spraying device are arranged in the cleaning device body; through the arrangement of the cleaning device and other structures, a double-shaft motor is started, the double-shaft motor drives a first chain wheel, a chain and a second chain wheel to rotate through a rotating shaft, the chain drives a sliding block to move, the sliding block drives a fixing block to move, and when the fixing block moves to one end of the chain, the sliding block slides in the fixing block so as to move to the chain on the lower portion; and then the fixed block is continuously driven to move reversely, so that the cleaning block is driven to move back and forth to clean the bottom of the therapeutic apparatus body, and the effect of automatic cleaning is achieved. By means of the technical scheme, the problems that in the prior art, no self-cleaning device exists, water resources are wasted during cleaning, and cleaning is inconvenient are solved.

An artificial structure for preventing or treating lymphedema and a construction method therefor. The artificial structure includes a first sheet and a second sheet arranged on the first sheet and including at least two channels. Each channel includes an inlet, an outlet, a one-way channel structure configured to maintain a one-way flow of lymph from the inlet toward the outlet, and a pattern on a surface facing the first sheet. The artificial structure is configured to maintain a normal flow of lymph despite the effects of lymphadenectomy and radiation exposure. The artificial structure has the effect of not only preventing the onset of lymphedema but also effectively being useful for treating diseases caused by interruption of lymph flow.

The invention relates to clinical medicine, and more particularly to lymphology, surgery, plastic surgery and oncology, for treating lymphatic swelling in the case of primary or secondary lymphoedema in adults and children, inter alia accompanied by infectious complications, and even more particularly relates to methods for treating lymphoedema and to the use of accessible drugs in the treatment of lymphatic swelling at any stage and in any location. The claimed method for the lymphotropic treatment of lymphoedema involves consecutively preparing an injectable drug composition A containing an adrenergic alpha-1 receptor agonist and a glucocorticoid, administering same by lymphotropic interstitial injection by puncturing the interstitial tissue of the lymphatic region of interest and introducing the drug composition, preparing an injectable drug composition B containing a cholinesterase inhibitor, administering same by lymphotropic interstitial injection by puncturing the interstitial tissue of the lymphatic region of interest and introducing the drug composition, and also, if necessary, preparing an injectable drug composition C containing bovhyaluronidase azoximer, and administering same by interstitial injection by puncturing the interstitial tissue of the lymphatic region of interest. The technical result consists in improving the drainage of free fluid from the tissues and reducing limb swelling in the case of lymphoedema.

The present invention relates to a method for constructing a lymphedema pathological network based on graph neural networks. First, collect medical imaging data, clinical records, and biomarker data of the lymphatic system of patients, and use image processing techniques to extract key features and structure them into nodes and edges of a graph; then, based on the anatomical structure and physiological functions of the lymphatic system, define the topological structure of the graph, and introduce multi-modal data fusion technology to combine imaging data and biomarker data; then, design a multi-layer graph convolutional network model for learning the patterns of lymph nodes and their connections, and introduce an attention mechanism; then, use the graph convolutional network for deep learning to extract hidden features of nodes and edges, and apply graph embedding technology to transform high-dimensional graph data into a low-dimensional space; finally, develop a graph-based anomaly detection algorithm for identifying pathological changes that are significantly different from common patterns, and combine time series analysis to predict the pathological progression of lymphedema.

The invention relates to application of an EZH2 inhibitor in preparation of a medicine for preventing and / or treating lymphedema. Experiments prove that the EZH2 inhibitor can remarkably inhibit the skin fibrosis symptom of a lymphedema subject for the first time, so that the progress of the lymphedema can be effectively blocked, and the purposes of relieving, relieving and / or improving the lymphedema and related symptoms are achieved. In addition, the inventor also finds that the EZH2 inhibitor has relatively good medication safety. Therefore, the EZH2 inhibitor is expected to become a candidate therapeutic drug for lymphedema and has great clinical application prospect and value.

The invention provides a limb lymphedema air pressure detector, and mainly relates to the technical field of limb lymphedema air pressure detection equipment. A limb lymphedema air pressure detector comprises a machine shell, supporting legs arranged at the bottom of the machine shell and a controller, a detection inner cylinder is arranged in the machine shell and communicated with a vacuum pump, an opening communicated with the detection inner cylinder is formed in the center of the top face of the machine shell, an elastic oversleeve is fixedly installed at the top of the opening, and the elastic oversleeve is fixedly connected with the controller. A gas inlet of the vacuum pump is fixedly connected with one end of a gas suction pipe, the other end of the gas suction pipe is communicated with the detection inner cylinder, and a gas volume flowmeter communicated with the gas suction pipe is arranged in the middle of the gas suction pipe. The device has the advantages that a negative pressure environment is formed through air exhaust of the vacuum pump, the air exhaust amount is measured in real time through the gas volume flow meter, the volume of limbs can be accurately measured, and compared with a traditional water replacement method, the water surface height reading error is avoided, and the edema degree detection accuracy is greatly improved.

The invention relates to a blood protein peptide composition for improving body type and posture symptoms, and belongs to the field of bioactive peptides. The blood protein peptide composition disclosed by the invention comprises an LMN polypeptide and an LTL polypeptide, the amino acid sequence of the LMN polypeptide is Leuu-Met-Asn; the amino acid sequence of the LTL polypeptide is Leuu-Thr-Leu (Leu-Thr-Leu). The blood protein peptide composition prepared by using the technical scheme of the invention can improve body type and posture symptoms caused by lymphedema, and shows good economic benefits and social benefits.

Systems, devices, and methods of connecting two anatomical structures to facilitate fluid communication between the structures may utilize percutaneous and / or endovascular entry routes to the anatomical structures so that they may be positioned proximate to one another and a channel for facilitating fluid communication between them may be formed. In some cases, a first anatomical structure is a vein and a second anatomical structure is a lymph node and, in these instances, the lymph node may be positioned proximate to the vein so that a channel that allows lymphatic fluid to drain into the vein may be formed as a way of treating and / or preventing lymphedema.

The utility model discloses a sliding type accurate positioning and measuring device for leg circumference and arm circumference of a lymphedema patient. The sliding type accurate positioning and measuring device comprises a first bearing plate, a second bearing plate, a baffle and a measuring assembly. The two sides of the upper surface of the first bearing plate are each provided with a first scale line, and the first scale lines extend in the length direction of the first bearing plate. The second bearing plate is connected to the tail end of the first bearing plate in a pivoted mode, the second bearing plate can be switched between a first state and a second state, when the second bearing plate is in the first state, the bottom face of the second bearing plate is attached to the bottom face of the first bearing plate, and when the second bearing plate is in the second state, the bottom face of the second bearing plate is attached to the bottom face of the second bearing plate. The upper surface of the second bearing plate and the upper surface of the first bearing plate are located on the same horizontal plane. The baffle is connected to the head end of the first bearing plate in a pivoted mode so as to block the palm or the sole of a patient, the baffle can be switched between a third state and a fourth state, when the baffle is in the third state, the baffle is attached to the upper surface of the first bearing plate, and when the baffle is in the fourth state, the baffle is attached to the lower surface of the first bearing plate. The baffle is perpendicular to the first bearing plate. The measuring assembly comprises a sliding block and a measuring belt, the sliding block is arranged in the middle of the upper surface of the first bearing plate and can slide in the length direction of the first bearing plate, and the measuring belt transversely penetrates through the upper end of the sliding block and can be drawn left and right to measure the arm circumference and the leg circumference. When the second bearing plate is in the second state, the measuring assembly can slide to the surface of the second bearing plate and move in the length direction of the second bearing plate. The device is simple in structure and convenient and accurate in measurement.

The invention relates to clinical medicine, and more particularly to lymphology, surgery, plastic surgery and oncology, for treating lymphatic swelling in the case of primary or secondary lymphoedema in adults and children, inter alia accompanied by infectious complications, and even more particularly relates to methods for treating lymphoedema and to the use of accessible drugs in the treatment of lymphatic swelling at any stage and in any location. The claimed method for the lymphotropic treatment of lymphoedema involves consecutively preparing an injectable drug composition A containing an adrenergic alpha-1 receptor agonist and a glucocorticoid, administering same by lymphotropic interstitial injection by puncturing the interstitial tissue of the lymphatic region of interest and introducing the drug composition, preparing an injectable drug composition B containing a cholinesterase inhibitor, administering same by lymphotropic interstitial injection by puncturing the interstitial tissue of the lymphatic region of interest and introducing the drug composition, and also, if necessary, preparing an injectable drug composition C containing bovhyaluronidase azoximer, and administering same by interstitial injection by puncturing the interstitial tissue of the lymphatic region of interest. The technical result consists in improving the drainage of free fluid from the tissues and reducing limb swelling in the case of lymphoedema.

1. The name of the design product: portable lymphedema treatment instrument. 2. The use of the design product: for lymphedema treatment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention is applicable to the technical field of biological medicine, and provides application of Akk bacteria in noninvasive early diagnosis of secondary lymphedema, the Akk bacteria are symbolic bacteria of normal people or animals, and when the symbolic bacteria of people or animals suffering from secondary lymphedema are changed, the abundance of the Akk bacteria is obviously reduced. By analyzing intestinal flora change caused by secondary lymphedema, a random forest sample classifier based on Akk bacteria abundance detection is successfully constructed, and the overall accuracy reaches 90% and is significantly higher than the baseline accuracy by 50%. The method not only realizes early noninvasive diagnosis of secondary lymphedema, but also provides a new biomarker detection means for clinic, can effectively solve the problem of lack of an effective noninvasive early diagnosis method in the prior art, and has a wide application prospect.

The utility model relates to the technical field of medical machinery, in particular to a lymphedema arm circumference measuring combined ruler which comprises at most three flexible rulers, the head of each flexible ruler is provided with a marking window and a hook-and-loop fastener surface, the marking windows are located on the sides of millimeter scale marks on the flexible rulers, marking lines are arranged above and below the marking windows, and the hook-and-loop fastener surface is provided with a hook-and-loop fastener surface. The mark line is connected with the mark window and is perpendicular to the mark window, the hook-and-loop fastener sticking face is located on the side, away from the millimeter scale line, of the mark window, the tail of each flexible ruler is provided with an observation window and a hook-and-loop fastener sticking face, and the observation windows are located above the millimeter scale line. The Velcro sticking surface and the Velcro sticking surface are positioned on different surfaces of the flexible rule and are matched with each other; each flexible ruler is provided with a fixing strip which is detachably connected with a connecting belt. The combined ruler for measuring the lymphedema arm circumference is simple in structure and convenient for people to measure, and the measuring speed is increased.

The utility model provides a lymphedema foot and finger-toe pressure treatment device through simulation manipulation, and relates to the technical field of medical care tools, the lymphedema foot and finger-toe pressure treatment device comprises a toe cavity and a foot cavity, the foot cavity comprises a foot sleeve body and a first air bag body, a zipper is connected between the two ends of the foot sleeve body, and the first air bag body is connected with the toe cavity. The first air bag bodies are arranged in an interlayer of the foot sleeve body, the multiple sets of first air bag bodies are arranged and are independent from one another, and a first inflation connector is arranged on one side of the foot sleeve body; the foot cavity and the toe cavity which are specially used for foot and toe treatment are designed, during use, the foot sleeve body is arranged on the outer side of a foot in a surrounding and sleeving mode, the toe sleeve body is arranged on the outer side of a toe in a sleeving mode, and the first air bag body and the second air bag body are inflated and deflated by connecting the first air bag body and the second air bag body through the first air guide pipe and the second air guide pipe. Therefore, refined lymphedema pressure treatment is carried out on the feet and the fingers and toes, and lymphatic circulation of the feet and the fingers and toes is improved.

The invention relates to the field of lymphatic vessel recognition, in particular to a lymphedema volume intelligent auxiliary measurement method and system, and the method comprises the steps: obtaining each initial lymphatic contrast region; analyzing the continuous condition of edge distribution and area distribution in the initial lymphatic contrast area to obtain a lymphatic swelling degree; obtaining an initial lymphedema area according to the lymphatic swelling degree; analyzing the extension condition of the form change direction of the initial lymphedema area in the suspected lymphatic vessel direction to obtain a radiography circulation direction; according to the radiography circulation direction, analyzing the distribution interval of the peripheral edge of the initial lymphedema area, and correcting the initial lymphedema area in combination with the lymphatic swelling degree to obtain a lymphedema area; and carrying out intelligent auxiliary volume measurement on the lymphedema area. According to the invention, the interference of part of normal lymphatic vessels on lymphedema information is reduced, and the measurement precision of the lymphedema volume is improved.

The invention provides a composite hydrogel for lymphatic tissue repair, which is formed by photo-crosslinking a gelatin-dopamine hydrogel capable of being subjected to methacrylic acid esterification, a lymph node acellular matrix and a photo-crosslinking initiator. The invention also provides a preparation method of the composite hydrogel, a re-cellularized hydrogel and application of the composite hydrogel and the re-cellularized hydrogel in preparation of a material for treating lymphatic tissue defects. By compounding the lymph node acellular matrix and the photo-crosslinkable gelatin dopamine hydrogel, a stent carrier which has natural biological signals, is suitable for a three-dimensional microenvironment and has good mechanical properties and in-situ forming characteristics is constructed, and an ideal platform is provided for field planting, growth and function exertion of ADSCs at a lymphatic tissue defect part; the ADSCs are assisted to play a repairing role in promoting lymphatic vessel regeneration and regulating a local microenvironment, and a novel composite hydrogel stent system adaptive to a cell repairing function is provided for treatment of related diseases such as lymphedema.

This invention relates to the field of biomedical technology and provides the application of taquimod in the preparation of drugs for regulating lymphatic inflammatory responses. Through bioinformatics analysis and cell experiments, this invention demonstrates that taquimod can specifically inhibit the abnormally activated S100A9 / RAGE signaling pathway in lymphatic inflammation, significantly reduce the expression of inflammatory factors, and effectively restore the proliferation, migration, and tube formation function of lymphatic endothelial cells. This provides a novel drug treatment approach based on molecular mechanisms for treating diseases related to lymphatic inflammatory responses such as lymphedema. Furthermore, taquimod, as an oral formulation with proven safety in clinical trials, exhibits good patient compliance and is suitable for long-term use. Compared to existing symptomatic treatments, it holds promise for fundamentally interrupting the vicious cycle of inflammation that drives disease progression, and thus has significant clinical application potential.

The invention relates to the technical field of medical detection equipment, and provides a device for measuring skin hardness for lymphedema, which comprises a shell, the front end of the shell is fixedly connected with a protective sleeve, the rear side of the top end of the shell is fixedly connected with a display screen, and the middle part of the top end of the shell is fixedly connected with three control buttons; the outer wall of the supporting frame is fixedly connected to the inner wall of the shell, the right side of the rear end of the supporting frame is connected with a movable frame through a driving assembly, the inner wall of the movable frame is slidably connected with a sliding rod, the front end of the sliding rod is fixedly connected with a sensor, and a spring is arranged on the outer wall of the sliding rod. The defects that a traditional palpation method cannot be quantized and is low in precision are overcome, a high-precision piezoresistive pressure sensor and a magnetic grid type displacement sensor are adopted in hardware, tiny pressure-displacement changes of the skin under the action of elastic force can be captured in real time, and software depends on an algorithm program established on the basis of a large amount of clinical lymphedema data. And the collected original signal can be converted into a specific skin hardness value.

The present application relates to the use of an EZH2 inhibitor in the preparation of a drug for preventing and / or treating lymphedema. The present application first discovers and proves by experiments that the EZH2 inhibitor can significantly inhibit the skin fibrosis symptoms of a lymphedema subject, thereby effectively retarding the progression of lymphedema, and further achieving the purpose of alleviating, relieving and / or improving lymphedema and its related symptoms. In addition, the inventors have also found that the EZH2 inhibitor has good drug safety. Therefore, the EZH2 inhibitor is expected to become a candidate therapeutic drug for lymphedema, and has great clinical application prospects and value.

The invention provides an internet-based lymphedema patient self-management support system and method, and belongs to the technical field of data processing, and the method specifically comprises the steps: determining a distribution processing scheme of medical staff when a patient sees a doctor based on the coincidence data and doctor seeing data of each patient in an online doctor seeing period, and carrying out the self-management of the patient on the basis of the distribution processing scheme; and when it is determined that the idle condition of the medical staff does not meet the requirement, whether the patient needs to be subjected to allocation optimization processing or not is determined according to the doctor-seeing matching condition of the patient not seeing the doctor and the medical staff in the idle state based on the allocation processing scheme of the patient, so that the self-management manual can more accurately reflect the demand of a user when being updated.

The invention relates to the technical field of medical instruments, and provides an intelligent lymphedema measuring instrument, which comprises a bracelet worn on an affected limb of a patient, a sensor module for collecting data, a data processing module, a built-in artificial intelligence algorithm and machine learning model, a built-in artificial intelligence algorithm, a built-in machine learning model, a built-in artificial intelligence algorithm and a built-in machine learning model, the early warning module is used for analyzing data of the sensor and recognizing early symptoms of lymphedema, the communication module supports Bluetooth and Wi-Fi wireless transmission, is integrated in an internal circuit of the bracelet, is used for being connected with a mobile terminal, a remote medical platform and a reminding module, sends out early warning and intervention instructions through vibration, sound and screen display, and is arranged on the surface of the bracelet. According to the method, comprehensive monitoring of relevant parameters of lymphedema is realized through cooperative data acquisition of multiple sensors and combination of establishment of a baseline data model, calculation of an edema risk index and identification of a spatial distribution abnormal mode, subtle changes of early symptoms of lymphedema can be accurately captured, and accuracy and reliability of early diagnosis are greatly improved.