The invention discloses a separator for bone-meat separation. The separator comprises a base box, wherein a separation cylinder is fixedly disposed above the base box, a transmission shaft extends into a feeding groove, and multiple first separation cutters are fixedly disposed on the transmission shaft; multiple second separation cutters are fixedly disposed at a section, close to the feeding groove, of a rotation shaft, and spiral auger blades are fixedly disposed on other sections of the rotation shaft; and multiple inner leak holes are formed in the separation cylinder, multiple outer leakholes and grooves are formed in an outer rotation cylinder, a guide rail is disposed in each groove, slide plates are movably disposed between the guide rails, a spring is connected and disposed between each slide plate and the bottom of each groove, and a brush is fixed on the side, remote from the spring, of each slide plate. The invention provides the separator for bone-meat separation, wherein particle sizes of separated meat can be adjusted and limited, the inner leak holes can be cleaned easily and effectively after use, operations are clean without odor, operations are simple, the structure is concise, and the separator is highly worthy for promotion.