The invention discloses a central speaker mesh assembly which comprises an outer shell, a top frame and a mesh core body, a supporting frame is annularly welded and fixed to the edge of the top of the outer shell, the top frame is arranged above the supporting frame, a groove is formed in the center of the interior of the top frame, the mesh core body is detachably installed in the groove, a supporting cylinder is fixed to the top of the top frame, and the supporting cylinder is fixed to the top of the top frame. A dustproof cover is fixedly welded to the top of the supporting cylinder, through holes are evenly formed in the outer side wall of the supporting cylinder, and the groove communicates with the supporting cylinder through a sound guide hole. The supporting cylinder with the through holes evenly formed in the outer side wall is fixed to the top of the top frame, and the dustproof cover is fixed to the top of the supporting cylinder, so that sound is guided out from the side face of the supporting cylinder, and dust accumulation on the top is avoided; meanwhile, the supporting cylinder is communicated with the groove through the sound guide hole, and a net core body composed of a first metal wire net, a dustproof filtering layer and a second metal wire net is arranged in the matched groove, so that dust can be effectively prevented.