The invention discloses a science and technology project intelligent declaration system based on cloud computing. The system comprises a three-layer architecture of a display layer, a business logic processing layer and a data layer, and further comprises a basic information input system, an accessory information input system and an RD input system. The basic information input system comprises anenterprise business information input module, an enterprise personnel information input module, an enterprise contract and invoice information input module, an enterprise product information input module and an enterprise intellectual property input information module. The accessory information input system comprises an enterprise qualification module; an audit report module; a personnel situationmodule; an intellectual property module; an achievement conversion module; an organization management module; an item establishment module and other honor modules; basic information input and attachment information input are carried out, the information is input from the display layer and stored in the data layer, and the input information is analyzed, called and integrated through the business logic processing layer and then previewed and exported on the display layer. The device is convenient to use, the labor intensity of declaration users is effectively reduced, and the working efficiencyof the declaration users is improved.