The invention relates to a method for seamless switch of mobile flow media transmission in the wireless mobile network, which uses multiple-path adaptive transmission speed regulation to realize the seamless switch of transmission layer, as dynamically regulating the layered multiple description video code strategy of flow media, according to the property of each path of multiple-path wireless access parallel transmission, to distribute the multiply-path transmission video code flow, and utilize the available band width of receiver most, to realize the stable transmission and smooth switch of transmission layer of mobile flow media. The invention can improve the band width, the transmission reliability, and reduce the network switch delay and the loss rate, to avoid the vibration which will affect the video quality of flow media. The invention can fully utilize present wireless network resource, with simple operation.