51 results about "Neurological therapy" patented technology

Devices and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache and trigeminal neuralgia and the like, by noninvasive electrical stimulation of nerves of the head, particularly supraorbital, supratrochlear, infraorbital, and mental nerves in the vicinity of their foramen or notch. The system comprises a handheld mobile device, such as a smartphone, that is applied to the surface of the patient's head. One or more electrodes on the mobile device apply electrical impulses transcutaneously through the patient's skin to the targeted nerve to treat the medical condition. The system is designed to address problems that arise particularly during self-treatment, when a medical professional is not present.

The present tools and methods for detecting, diagnosing, predicting, prognosticating, or treating a neurobehavioral phenotype in a subject. These tools and methods relates to a genotype and neurophenotype topography-based approach for analyzing brain neuroimaging and gene expression maps to identify drug targets associated with neurobehavioral phenotypes and, conversely, neurobehavioral phenotypes associated with potential drug targets, to develop rational design and application of pharmacological therapeutics for brain disorders, and to provide methods and tools for treatment of subjects in need of neurological therapy.

A method for treating a nasal airway to ameliorate one or more symptoms of rhinitis in a patient may involve advancing a treatment tip of a treatment device into a nostril of the patient, contacting nasal mucosa with the treatment tip at a first location overlying an anterior ethmoidal nerve, delivering energy from the treatment tip, to change a property of the anterior ethmoidal nerve, and removing the treatment tip from the nostril.

A method for treating nerves in a nasal cavity starts with identifying a patient having a condition occurring outside the nasal cavity. The method then involves activating a console attached to a radiofrequency stylus, advancing a distal tip of the radiofrequency stylus into a nostril of the patient, contacting nasal mucosa lining the nasal cavity with a treatment surface of the distal tip, and delivering radiofrequency energy from one set of bipolar electrodes on the treatment surface of the distal tip to a second set of bipolar electrodes on the treatment surface, to treat at least one nerve underlying the nasal mucosa. Treating the nerve (or nerves) involves modulating activity of the nerve to ameliorate the condition occurring outside the nasal cavity.

The present disclosure relates to a therapeutic system and methods of using the therapeutic system. In particular, the present disclosure relates to a system for improving an oral feeding ability of a patient including an assessment device to contact a patient and collect data related to an oral feeding ability of the patient, a computing device containing a processor to execute an assessment and therapy application, and the assessment and therapy application to receive the data related to the oral feeding ability, predict one or more areas of neurological muscle activity that need further development, and develop a neurological therapy treatment for improving the one or more areas of neurological muscle activity that need further development.

Restless Leg Syndrome (RLS) or Periodic Limb Movement Disorder (PLMD) can be treated using high frequency (HF) electrostimulation. This can include selecting or receiving a subject presenting with RLSor PLMD. At least one electrostimulation electrode can be located at a location associated with at least one of, or at least one branch of, a sural nerve, a peroneal nerve, or a femoral nerve. HF electrostimulation can be delivered to the subject, which can include delivering subsensory, subthreshold, AC electrostimulation at a frequency that exceeds 500 Hz and is less than 15,000 Hz to the location to help reduce or alleviate the one or more symptoms associated with RLS or PLMD. A charge-balanced controlled-current HF electrostimulation waveform can be used.

The invention relates to the technical field of medical instruments, in particular to a radio frequency treatment guide plate for trigeminal nerve treatment, and aims to overcome the defects that in the prior art, the puncture direction and depth are determined by means of anatomical mark points of a human body, the accuracy is poor, the effect is unstable, complications are prone to occurring, and a patient is injured to a certain extent due to repeated fluoroscopy during an operation. According to the technical key points, the equipment comprises an occlusion plate which is arranged in a semicircular shape and corresponds to the tooth part of a patient in shape for occlusion and fixation to realize positioning; a positioning column provided with a positioning hole, wherein the positioning hole corresponds to the position of the nose tip of the patient so as to detect the positioning accuracy; an injection channel which is located on one side of the occlusion plate and is 20-30 mm away from the mouth corner, wherein the injection channel has the approach direction reaching the skull base oval hole and is used for enabling the injection needle to reach the trigeminal ganglion through guiding puncture of the injection channel; and a connecting part, wherein one end of the connecting part is connected with the injection channel, and the other end is connected with the joint part of the occlusion plate and the positioning column, so that the whole treatment guide plate is integrally formed.

An apparatus and method for performing neurological intervention are provided. The apparatus comprises a cylindrical body including a tapered threaded portion that screws into a pre- drilled hole in asubject. Additionally, the apparatus includes a connector including a probe lock-screw that is disposed on the cylindrical body, at an end opposite to the tapered threaded portion. The connector further includes an opening to receive a probe. The probe is inserted into a subject via the apparatus, and a depth of insertion of the probe within the subject is adjusted by the probe lock-screw.

A peripheral nerve stimulator to stimulate a peripheral nerve to treat essential tremor and other movement disorders, as well as overactive bladder, cardiac dysfunction and neurotransmitter dysfunction is provided. The peripheral nerve stimulator can be a noninvasive surface stimulator to provide multi-modal optimized therapy. Stimulation can be vibrational, electromechanical, thermal, radiant, electrical, magnetic, electromagnetic, light, mechanical, chemical, thermal, ultrasonic, radiofrequency (RF), acoustic, infrared, ultraviolet, x-ray, and / or microwave. Stimulation can be delivered using an open loop system and / or a closed loop system with feedback. Stimulation can be to one site or multiple sites.

A system and method for brainwave entrainment therapy that allows for targeted treatment of particular areas of the brain, particular neurological functions, particular neurological states, and combinations of areas, functions, and states. The system and method receive a neurological assessment identifying areas of the brain or neurological functions to be treated, select one or more treatment modalities and frequencies, select a treatment regimen, and apply brainwave entrainment using the modalities, frequencies and regimen while the subject engages in dual-task activities selected to stimulate the areas of the brain, neurological functions, or neurological states to be treated, enhanced, or altered.

Variable amplitude signals for neurological therapy, and associated systems and methods are disclosed. A representative method includes activating automatic delivery of an electrical therapy signal to a patient's spinal cord region at a frequency in a frequency range between 1.5 kHz and 100 kHz, via at least one signal delivery contact carried by an implanted signal delivery device. The delivery can include repeatedly and automatically delivering the electrical therapy signal at each of multiple therapy signal amplitudes to the at least one signal delivery contact, without the therapy signal generating paresthesia in the patient. The foregoing process can be used as a screening tool to screen responders from non-responders in the context of a non-paresthesia-generating therapy, and / or can be used during long-term treatment, for example, for chronic pain.

A system and method for targeted neurological treatment using brainwave entrainment therapy with passive treatment that allows for targeted treatment of particular areas of the brain, particular neurological functions, particular neurological states, and combinations of areas, functions, and states. The system and method receive gait parameters for an individual and compare those against a database of historical gait data to determine if an onset neurodegenerative condition is present, and applies a brainwave entrainment therapy responsive to the determination of the condition. The system and method receive a neurological assessment identifying areas of the brain or neurological functions to be treated, select one or more treatment modalities and frequencies, select a treatment regimen, and apply brainwave entrainment using a treatment regimen while the subject engages in dual-task activities selected to stimulate the areas of the brain, neurological functions, or neurological states to be treated, enhanced, or altered.

A system and method for brainwave entrainment therapy that allows for targeted treatment of particular areas of the brain, particular neurological functions, particular neurological states, and combinations of areas, functions, and states. The system and method receive a neurological assessment identifying areas of the brain or neurological functions to be treated, select one or more treatment modalities and frequencies, select a treatment regimen, and apply brainwave entrainment using the modalities, frequencies and regimen while the subject engages in dual-task activities selected to stimulate the areas of the brain, neurological functions, or neurological states to be treated, enhanced, or altered.

Disclosed herein are methods that use a vitamin D analogue to treat a neurological disorder. Additionally, pharmaceutical compositions comprising a vitamin D analogue and a neurotherapeutic agent are disclosed, and methods of using the same. The pharmaceutical compositions and methods of the invention are useful for the treatment of a neurological disorder, for example, Alzheimer's disease, multiple sclerosis, Parkinson's disease, epilepsy, neuropathic pain, or other conditions that affect the central or peripheral nervous system of a subject.

The invention discloses a massage device for the neurology department. The massage device comprises a massage device base, a lifting device, a lifting control pedal, a massage chair main body, a massage chair cushion, a nerve massage pillow and a liquid medicine atomization device; the lifting device is arranged at the bottom of the massage chair main body, and medical staff can control lifting of the massage chair through the lifting control pedal; the medical staff can conveniently examine the body of a patient at any time, and movement of the medical staff is reduced; the liquid medicine atomization device is arranged on the massage device base, liquid medicine is atomized through the liquid medicine atomization device and then inhaled by the patient, atomization treatment and massage treatment are combined, and the massage treatment effect is better; all parts of the body of the patient are massaged through electric massage balls, manual massage of medical staff is not needed, and the workload of the medical staff is greatly reduced; and acupuncture points of the head of the patient are massaged through the nerve massage pillow, the nerve treatment effect is guaranteed, massage and body massage are conducted at the same time, and the massage treatment efficiency is improved.

Example systems and techniques for denervation, for example, renal denervation. In some examples, a processor determines one or more tissue characteristics of tissue proximate a target nerve and a blood vessel. The processor may generate, based on the one or more tissue characteristics, an estimated volume of influence of denervation therapy delivered by a therapy delivery device disposed within the blood vessel. The processor may generate a graphical user interface including a graphical representation of the tissue proximate the target nerve and the blood vessel and a graphical representation of the estimated volume of influence.

The invention discloses trigeminal nerve electrical stimulation equipment and a use method thereof, and relates to the technical field of nerve treatment.The trigeminal nerve electrical stimulation equipment comprises an electrical stimulator and a remote controller, the electrical stimulator is fixedly connected with a connector, a wire is inserted into the connecting end of the connector, the connector fixes the wire, and the connector is connected with the remote controller. The outer side of the tail end of the wire is fixedly connected with a plurality of electrode slices, the outer side of the wire is fixedly connected with a plurality of anchor points located at the front ends of the electrode slices, and the remote controller is in wireless communication connection with the electrical stimulator. The device can be buried in the body of a patient for a long time, so that the effect of inhibiting the pain of the patient can be guaranteed, multiple operations for inhibiting the pain of the patient are not needed after one operation when the pain fed back by the patient still exists, and the damage to the body of the patient is reduced.

Systems and methods for adjusting neural therapy patterns of a neuromodulation system in response to each of patient events and passage of time. Initial stimulation parameters are set and used to start a stimulation period. As time passes or events occur, the neuromodulation system adjusts the stimulation parameters according to a preset temporal pattern. Further examples include handling of patient requests for therapy changes, and acute testing for complex stimulation patterns.

Variable amplitude signals for neurological therapy, and associated systems and methods are disclosed. A representative method includes activating automatic delivery of an electrical therapy signal to a patient's spinal cord region at a frequency in a frequency range between 1.5 kHz and 100 kHz, via at least one signal delivery contact carried by an implanted signal delivery device. The delivery can include repeatedly and automatically delivering the electrical therapy signal at each of multiple therapy signal amplitudes to the at least one signal delivery contact, without the therapy signal generating paresthesia in the patient. The foregoing process can be used as a screening tool to screen responders from non-responders in the context of a non-paresthesia-generating therapy, and / or can be used during long-term treatment, for example, for chronic pain.

A system and method for targeted neurological therapy using a primary task and a plurality of associative activities, wherein the associative activities provide social engagement as a therapeutic element. The system and method receive various biometric data associated with an individual performing a multiple-task stimulation therapy regimen, computes a performance score for the individual, and makes adjustments to the therapy regimen based on the performance score. In some implementations, the system is supported by one or more machine learning predictive models configured to generate therapy regimen adjustment recommendations.

The invention relates to the technical field of child neurotherapy, and provides a biomarker for diagnosing child epilepsy, which comprises colloidal fibrillary acidic protein with a concentration threshold of more than or equal to 12.5 ng / mL miR-124-3p by adopting a chemiluminescence immunoassay method, and with a concentration threshold of less than or equal to 0.45 times by adopting an RT-qPCR method; a high performance liquid chromatography method is adopted, and the concentration threshold value of the gamma-aminobutyric acid is smaller than or equal to 1.8 [mu] mo l / L. Preferably, the synergistic effect of the colloidal fiber acidic protein, the miR-124-3p and the gamma-aminobutyric acid meets the requirement. Colloidal fibrillary acidic protein, miR-124-3p and gamma-aminobutyric acid are jointly detected, a diagnostic index is introduced, the sensitivity reaches 95.0%, the specificity is 93.3%, the sensitivity is improved by about 30% compared with traditional single marker detection, the whole process is shorter than or equal to 25 minutes, the efficiency is remarkably improved compared with traditional EEG monitoring and gene detection, the size of the kit integrates a micro-fluidic chip and an AI algorithm, and the detection accuracy is greatly improved. The method is suitable for bedside detection of primary medical institutions.

A severed nerve may be surgically rejoined and severed axons fused via sequential administrations of solutions. The solutions may include a priming solution comprising methylene blue in a Ca2+-free saline solution, a fusion solution comprising about 50% (w / w) PEG, and a sealing solution comprising Ca2+-containing saline. The PEG fusion solution may be applied in a nerve treatment device configured to isolate the injured segment of the nerve. The device may include a containment chamber for creating a fluid containment field around the anastomosis. The device may have slits, slots, and / or apertures in opposing endwalls of the device designed to receive the nerve. The device may have an open bath configuration or may include separable lower and upper bodies to create a closed bath configuration. The device may include one or more fluid ports in fluid communication with the containment chamber for introducing and / or removing fluid.

A system and method for dual-task neurological therapy using a combination of primary and secondary tasks to facilitate neurogenesis and neuroplasticity in targeted regions of the brain using computer-enhanced dual-task analysis and treatment. The system and method involve having a subject engage in primary and secondary tasks at levels of intensity or stress associated with increased neurogenesis and neuroplasticity. In some embodiments, novel secondary tasks are selected to vary the tasks to help with neurogenesis and neuroplasticity, novel content for the secondary tasks are generated by a generative AI model, adjustments are made to the tasks during performance using a feedback mechanism to adjust for the abilities and performance of the patient, and empathetic feedback is generated by a generative AI model and provided to the patient during performance of tasks.

The invention belongs to the technical field of nerve treatment instruments, and particularly relates to a clinical therapeutic apparatus for neurology department. The clinical therapeutic apparatus can be used for soothing nerves of a user, so that nerve diagnosis and treatment can be conveniently carried out on the user; the invention provides the clinical therapeutic apparatus, which comprises a nursing bracket, a placing plate, a hollow frame, an overhead plate, a head cushion block, a sliding plate, an arm supporting plate, a rubber sleeve and hollow connecting balls, and is characterized in that the nursing bracket is mounted on a nursing bed, the placing plate is arranged on the nursing bracket, and the overhead plate and the head cushion block are mounted on the placing plate; the overhead plate is used for supporting the trunk of the user, the hollow frame is installed at the lower end of the placing plate and suspended on the outer side of the nursing bed, a sliding plate is slidably connected to the hollow frame, an arm supporting plate is installed on the sliding plate, a plurality of hollow connecting balls are arranged on the rubber sleeve, a meridian pressing assembly used for relieving nerves of the user is arranged on the rubber sleeve, and the rubber sleeve is installed on the arm supporting plate.

The invention discloses sacral nerve electrical stimulation equipment and a use method thereof, and relates to the technical field of nerve treatment.The sacral nerve electrical stimulation equipment comprises a pulse generator, a connector is fixedly connected to the top of the pulse generator, a wire is installed in the connector, a catheter sleeves the outer side of the wire, a plurality of electrodes are arranged on the outer side of the tail end of the wire, and the electrodes are electrically connected with the pulse generator. The sacral nerve electrical stimulation device comprises a pulse generator, a connector and a wire, a main patch is placed on the surface of the pulse generator, a through hole is formed in the surface of the main patch, a mounting cabin is fixedly connected to the surface of the pulse generator, and one end of the mounting cabin extends to the outer side of the through hole. The electrode can be implanted into the body of a patient, meanwhile, when not in use, the electrode and the wire can be pulled out of the body of the patient, the electrode and the wire do not need to be embedded into the body of the patient, and the device can be pulled out during short-term treatment and poor treatment effect.

A neurological treatment apparatus includes a first endovascular device comprising a plurality of first electrodes extending along a first length in a distal portion of the first device, the distal portion of the first device being configured for endoluminal navigation into cerebral vasculature, and a second endovascular device comprising a plurality of second electrodes extending along a second length in a distal portion of the second device, configured for endoluminal navigation into the cerebral vasculature, such that electrostimulative current may be passed between the first and second electrodes.

The invention belongs to the technical field of cranial nerve treatment devices, and provides a cranial nerve treatment device for the neurology department to solve the technical problems that the position of a treatment part on an existing treatment device cannot be adjusted, the treatment part cannot be well attached to the head of a patient, the angle of a display screen cannot be adjusted, and medical staff cannot observe the treatment part conveniently. Comprising a base, universal wheels, a display screen and a microwave generator and further comprises a lifting adjusting mechanism, a transverse moving adjusting mechanism, a head circumference clamping mechanism, an angle adjusting mechanism, a driving mechanism, a U-shaped channel and a channel opening and closing mechanism, and the lifting adjusting mechanism is arranged at the top of the base 1; the transverse moving adjusting mechanism is connected with the lifting adjusting mechanism; the head circumference clamping mechanism is connected with the transverse movement adjusting mechanism; the angle adjusting mechanism is connected with the display screen; the driving mechanism is connected with the head circumference clamping mechanism and the angle adjusting mechanism; the U-shaped channel is formed in the base 1; the channel opening and closing mechanism is arranged on the base 1. The head of a patient can be fixed, and the angle of the display screen can be adjusted.

The invention discloses a device for auxiliary treatment of motor nervous system damage, which comprises an auxiliary treatment device, a treatment cabin, a head support mechanism, a nerve treatment patch and a telescopic silver needle mechanism, a base is arranged on the auxiliary treatment device, and the treatment cabin, a controller and a medicament cabin are arranged above the base. A head supporting mechanism, a body physical therapy plate, a thigh supporting plate, a shank supporting plate and a foot driving plate are arranged in the treatment cabin, nerve treatment pastes are arranged on the body physical therapy plate, the thigh supporting plate and the shank supporting plate in a matched mode, a control connecting wire harness is arranged between the nerve treatment pastes and the controller, and acupuncture mounting base cloth is arranged on the nerve treatment pastes. According to the auxiliary treatment equipment, the whole body of a patient can be subjected to motor nervous system treatment, directional treatment can also be carried out, acupuncture, medicine, electromagnetic physical therapy and auxiliary driving limb movement treatment are adopted for auxiliary treatment, multiple methods are adopted for auxiliary treatment, and the treatment effect is good.