The invention discloses a full-automatic cotton quilt production line which comprises a feeding frame mechanism, an automatic seam quilting machine, a cutting machine, a covering machine and a covered edge conveying frame mechanism.The feeding frame mechanism, the automatic seam quilting mechanism, the cutting machine and the covering machine are sequentially and transversely arranged.The covered edge conveying frame mechanism is arranged in the covering machine.The feeding frame mechanism comprises a batching and storing frame body, a plurality of batching roller assemblies, a plurality of power roller assemblies, a plurality of pressing roller assemblies and a batching speed reducer.The automatic seam quilting machine comprises a seam quilting machine frame, a driving wheel assembly, a driven wheel assembly, a seam quilting machine head assembly and an auxiliary wheel assembly.By using the feeding frame mechanism, the automatic seam quilting machine, the cutting machine, the covering machine and the covered edge conveying frame mechanism in cooperation, the procedures of feeding, seam quilting, cutting, covering, covered edge conveying and the like are automatically completed, the automation of all the procedures in the cotton quilt production process is achieved, labor waste is effectively reduced, production efficiency is improved, and product quality is improved.