The invention belong to the technical field of aluminum alloy profile and concretely relates to a manufacturing method for slide rail hollow profile for robot arm movements with aluminum alloy replacing steel. The manufacturing method comprises first, analyzing steel connection member motion and stress conditions, second, selecting aluminum-alloy material, third, designing hollow profile, fourth, simulating aluminum profile connection member motion and stress conditions by a computer to determine whether the hollow profile meets demands, fifth, selecting an extruding machine and designing an aluminum alloy hollow profile connection member via a die, sixth, casting aluminum alloy ingot, seventh, extruding aluminum alloy hollow profile connection member and conducting online quenching, eighth, conducting aluminum alloy hollow profile connection member tension extension and aging treatment, ninth, sampling and checking the aluminum alloy hollow profile connection member, and tenth, hardening and packing the aluminum alloy hollow profile. Motion and stress conditions of the aluminum alloy hollow profile connection member can be simulated by the computer; strength and plasticity meet use requirements; and hollow profile can be manufactured in batches by the use of the method.