The invention provides a wear resistance steel plate, which contains the chemical ingredients (by weight percent) of: 0.31 to 0.40% of C, 0.10 to 0.80% of Si, 0.20 to 1.50% of Mn, not more than 0.050% of P, not more than 0.030% of S, 0 to 1.50% of Cr, 0 to 0.80% of Mo, 0.02 to 0.20% of Al, 0.0005 to 0.0040% of B, 0 to 0.10% of Ti, 0 to 0.030% of Ca, the balance of Fe and unavoidable impurities, wherein Cr+Mo is not less than 0.10% and not more than 1.80%, and Al+Ti not less than 0.05% and not more than 0.18%. A manufacturing method of the wear resistance steel plate comprises the steps of smelting, refining, casting, rolling, quenching, tempering and the like. The 550 HB-level wear resistance steel plate, which is obtained from the ingredients and process, has high hardness (not less than550 HB), can be welded and bent, and includes the microstructure of martensite or martensite and residual austenite. The steel plate has superior wear resistance and is extremely suitable for workingunder strong wear environment, especially on vehicles or facilities, like buckets, loaders, mining electric wheel dump tracks and the like, which come into contact with high-hardness materials, such as high strength ore and the like.