44 results about "Aspiration fluid" patented technology

To improve allele discrimination, the inventors adapted the system combining Cas13a detection sensitivity with allele-specific PCR amplification to propose CASPER (Cas13a Allele-Specific PCR Enzyme Recognition) as a new versatile, easy-to-implement, and highly sensitive method to detect low-frequency of sequence variant. CASPER enabled specific and sensitive detection of KRASG12D with low DNA input such as DNA extracted from patient's pancreatic ultrasound-guided fine-needle aspiration fluids. CASPER is easy to implement and a versatile reliable method virtually adaptable to any point mutation.

A nasal irrigation device includes a clean liquid tank, a waste liquid tank, a tubing assembly, first and second nasal inserts, a first motorized pump coupled to the clean liquid tank and the tubing assembly structured to draw liquid from the clean liquid tank and pump the liquid to the tubing assembly and to the first nasal insert with positive pressure when the first nasal insert is fixedly or removably coupled to the tubing assembly, and a second motorized pump separate from the first motorized pump and coupled to the waste liquid tank and the tubing assembly structured to draw waste liquid from the tubing assembly and the second nasal insert with negative pressure when the second nasal insert is fixedly or removably coupled to the tubing assembly and provide the waste liquid to the waste liquid tank.

A system for detecting intraocular pressure events during phacoemulsification surgery having a surgical console, a handpiece having a proximal end being communicatively connected to an irrigation line and an aspiration line; a first sensor in communication with the aspiration line or the irrigation line for providing a first measurement value; and a second sensor in communication with the aspiration line for providing a second measurement value; and wherein at least one characteristic of the irrigation fluid or aspiration fluid in their respective lines is changed in accordance with the difference between the first measurement value and the second measurement value. A system for calibrating patient eye level and wound leakage; detecting occlusion or post occlusion surge; determining BSS usage or remaining in a container; and detecting a fluid line abnormality using a first sensor and a second sensor in different configurations and differences in first and second measurement values.

Phacoemulsification apparatus having a phacoemulsification probe that has a needle with a distal tip configured to be inserted into an eye lens, the needle having a lumen. The probe has an actuator configured to vibrate the needle, an aspiration channel, coupled with the lumen and configured to convey an emulsified particle of the lens as aspiration fluid, and an aspiration sensor, coupled with the aspiration channel and configured to measure a vacuum level within the aspiration channel. A microscope is configured to capture an image of the distal tip and of the emulsified particle. A processor is configured to provide an analysis of the image, and, in response to the analysis, when the emulsified particle is in contact with the distal tip for at least a preset time period while the vacuum level is below a predetermined threshold, energize the actuator with a pulse of energy.

This utility model belongs to the field of medical device technology, and particularly relates to a cytokine flow cytometry detection kit, including a reagent bottle and a storage box. The reagent bottle is snapped into a limiting tube. A partition plate is snapped into the inside of the storage box, and a bottle holder slot is opened on the partition plate. The bottom of the reagent bottle is inserted into the bottle holder slot. A limiting cardboard is movably set on the inner wall of the storage box. The bottom of the partition plate abuts against the bottom of the inner wall of the storage box, and the top abuts against the bottom of the limiting cardboard. In this utility model, the limiting tube can limit the pipette tip, preventing the pipette tip from falling into the reagent bottle during the process of using the pipette to draw liquid, which would prevent the operator from being unable to quickly remove the tip. The limiting cardboard can limit the top of the partition plate, preventing the partition plate from being pulled out with the bottle when the operator pulls the reagent bottle out of the bottle holder slot.

To provide a liquid absorption tool capable of successively absorbing a liquid within a body by suppressing complication of operation by an operator concerning an endoscopic operation.SOLUTION: A liquid absorption tool 1 used in an endoscopic operation to absorb a liquid 80 within the body of a patient 60 comprises: a tube 10 which is inserted into the body via a trocar 50 installed on a body surface 70 of the patient 60, has a hole 13 on one end 11 side, and is capable of performing suction from the other end 12; and a sponge body 20 which is connected to the one end 11 side of the tube 10, surrounds the one end 11 side of the tube 10, and has liquid absorption property and flexibility.SELECTED DRAWING: Figure 2

Improvements in a fluid pump systems are disclosed for a disposable pump cassette with pneumatically actuated diaphragm pumps and valves in general, and a peritoneal dialysis cycler using a disposable pump cassette in particular. Pump fluiding is improved by detecting leaks in one or more port valves. A method to flush a leaking port valve to reduce leakage at the port valve is disclosed. The method to flush the port valve starts by occluding the line connected to the port valve, then alternatingly pumping liquid toward the port valve and then pulling liquid from the leaking valve. The port valve may be open while liquid is pumped toward the port valve and closed while liquid is pulled from the port valve.

A vent valve, and a vent valve assembly, for a liquid dispensing container, employ a vent disc having small open vent holes in cooperation with an overlying thin flexible flap that covers and closes the vent holes to limit liquid pressure on the holes when the container is upright, yet require little suction pressure to move the flap to draw liquid or vent through the holes. The vent valve can be used in a bottom cap that is attachable to the bottom open end of the container. The vent valve assembly includes such a bottom cap, a sealing member for sealing the bottom cap to the container, and a vent valve. The vent valve and / or bottom cap have an elevated vent disc and a top portion having the thin flexible flap.

Improvements in a fluid pump systems are disclosed for a disposable pump cassette with pneumatically actuated diaphragm pumps and valves in general, and a peritoneal dialysis cycler using a disposable pump cassette in particular. Pump fluiding is improved by detecting leaks in one or more port valves. A method to flush a leaking port valve to reduce leakage at the port valve is disclosed. The method to flush the port valve starts by occluding the line connected to the port valve, then alternatingly pumping liquid toward the port valve and then pulling liquid from the leaking valve. The port valve may be open while liquid is pumped toward the port valve and closed while liquid is pulled from the port valve.

In some examples, a medical aspiration system is configured to control medical aspiration based on a cardiac cycle of a patient. For example, a medical aspiration system can comprise a suction source configured to apply a suction force to a catheter to remove fluid from the catheter, and control circuitry configured to control the suction force applied by the suction source to the catheter based on a cardiac cycle of a patient.

A system for automated biopsy analysis is provided. The system includes a biopsy needle holder and delivery system configured to secure a biopsy needle, a sample transfer system configured to transfer a biopsy sample from the biopsy needle to a well of a multi-well plate, a liquid handling system configured to dispense and aspirate liquid to and from the well of the multi-well plate, an optical measurement system configured to measure a fluorescent signal from the well, and a control system configured to control operation of the biopsy needle holder and delivery system, the sample transfer system, the liquid handling system, and the optical measurement system. The system enables automated processing and analysis of biopsy samples, improving efficiency and reproducibility of metabolic rate determination and other tissue analysis.

Drainage device, comprising a vacuum pump (1), a suction line (2) connected to this vacuum pump (1), a gas-tight liquid collection container (6) which is connected to the suction line (2) and serves to reliably maintain the negative pressure and to collect extracted liquid, a suction pipe (5) which is connected to a rear area of ​​a hollow cover element (3) which is open at its front and which opens into the liquid collection container (6) at its end facing away from the cover element (3), characterized by the fact that the cover element (3) has a sponge pad (4) at its front opening, wherein the sponge pad (4) absorbs fluid from the wound area and distributes a negative pressure evenly, wherein the negative pressure generated by the vacuum pump (1) via the suction line (2) first reaches the fluid collection container (6) and from there is directed via the suction tube (5) to the cover element (3) and further to the sponge pad (4), while the fluid absorbed from the wound area is transported via the sponge pad (4) and through the suction tube (5) into the fluid collection container (6).

Fluid management systems are disclosed that include software-controlled, electro-mechanical devices used in combination with single-use or multi-use tubing sets. Functions of the fluid management systems can include fluid pressurization, fluid warming, fluid deficit monitoring (including flow-based and weight-based), suction, fluid collection, and fluid evacuation (including indirect-to-drain and direct-to-drain options). The systems can be configured based on the surgical environment (e.g., operating room or physician office) as well as other user needs and / or preferences.

The application discloses a kind of negative pressure suction gun, manual negative pressure suction method, it is related to biomedical engineering technical field, the gun handle of negative pressure suction gun is reciprocated and opened and closed to drive suction pumping section to reciprocate in negative pressure sedimentation cavity Negative pressure suction and extrusion pumping, negative pressure sedimentation cavity can pass through liquid suction pipe one-way liquid suction when negative pressure suction, negative pressure sedimentation cavity can be one-way liquid delivery to the liquid storage part when extrusion pumping, so as to be used for suction liquid and soft solid tissue in liquid by setting negative pressure sedimentation cavity, then by adjusting increase negative pressure suction force, the viscosity of solid tissue that can be sucked is also greater, so that the negative pressure suction gun of the application can not only be used for endometrial gynecological field liquid suction and solid tissue sampling, but also can be used for closed narrow space tumor biopsy, brain tissue and other solid-liquid components suction, during suction process, by rotating liquid suction pipe, the inlet slope of liquid suction pipe is realized 360 degree rotation, to avoid suction dead angle.

The invention belongs to the technical field of medical apparatus and instruments, and particularly relates to a special-shaped multi-cavity visual bending-adjustable multi-parameter monitoring cavity device. The device is composed of an operation unit, a bundling pipe and a bending adjusting unit, the bundling pipe is inserted into a cavity channel for cleaning, suction, endoscopy and the like, the bending adjusting unit can check all angles in the cavity channel, and the operation unit controls the turning angle of the bending adjusting unit and liquid suction of the bundling pipe; the functions of the operation unit are optimized and enhanced, the clinical application range of the device is expanded, the device is complete in function and convenient and fast to operate, a clear and visual diagnosis and treatment means for lesions in the cavity is provided for medical staff, the scientificity, safety, convenience, high efficiency, intelligent characteristics and operation accuracy of the device remarkably improve the medical work efficiency, and the clinical application range of the device is widened. And a more accurate and safer diagnosis and treatment service is provided for the patient.

The application discloses a flushing and sealing pipe device in the technical field of medical auxiliary devices, which comprises a liquid supply component, a driving pump and a hose. The liquid supply component is installed on the pump shell of the driving pump, which improves the integration of the flushing and sealing pipe device and makes the flushing and sealing pipe device convenient to store or carry. The two ends of the hose are respectively connected with the liquid supply component and the intravenous catheter, and the middle part of the hose is arranged in the interior of the pump shell, so that the hose does not need to be disconnected with the intravenous catheter for multiple times for sucking liquid, the number of interface exposure is significantly reduced, and the risk of intravenous catheter pollution is significantly reduced. The rotary pump head in the interior of the pump shell extrudes the hose, so that the liquid in the liquid supply component flows to the intravenous catheter to flush and seal the pipe. The steps of sucking, disinfecting, exhausting, bolus injection and the like are omitted, the flushing and sealing pipe operation is more convenient and fast, the artificial operation time is reduced, and the threshold of the flushing and sealing pipe operation is lowered.

An ophthalmic surgical system includes: a first position sensor for detecting a first deflection position of the first elastic partition element, a second position sensor for detecting a second deflection position of the second elastic partition element, a first pressure sensor for detecting a first pressure in a first drive fluid line, a second pressure sensor for detecting a second pressure at an outlet of a first pump chamber and / or a third pressure sensor for detecting a third pressure at an inlet of a second pump chamber, a fourth pressure sensor for detecting a fourth pressure in the second drive fluid line, a direct connection line configured to connect the irrigation fluid line to the aspiration fluid line, a processing unit for processing the first pressure, the second pressure and / or the third pressure, the fourth pressure, in each case dependent on the first and the second deflection position.

Phacoemulsification apparatus having a phacoemulsification probe that has a needle with a distal tip configured to be inserted into an eye lens, the needle having a lumen. The probe has an actuator configured to vibrate the needle, an aspiration channel, coupled with the lumen and configured to convey an emulsified particle of the lens as aspiration fluid, and an aspiration sensor, coupled with the aspiration channel and configured to measure a vacuum level within the aspiration channel. A microscope is configured to capture an image of the distal tip and of the emulsified particle. A processor is configured to provide an analysis of the image, and, in response to the analysis, when the emulsified particle is in contact with the distal tip for at least a preset time period while the vacuum level is below a predetermined threshold, energize the actuator with a pulse of energy.

The invention relates to a method and an apparatus for pre-cleaning an endoscope. There is provided a method for pre-cleaning an endoscope, the method comprising: providing an endoscope comprising a channel system, the channel system comprising: a first channel section, a second channel section and a third channel section and a first channel opening, a second channel opening and a third channel opening, where the channel sections are connected to each other at a channel connection; connecting each of a liquid source, in particular a container containing a liquid, a suction device, preferably a suction pump, and a sealing element to a different one of the first channel opening, the second channel opening and the third channel opening, wherein the liquid source comprises a containing chamber having a variable containing chamber volume; the suction device is activated for aspirating liquid from the liquid source towards the suction device, where during aspiration of liquid from the liquid source, the accommodation chamber volume of the accommodation chamber is reduced, preferably the volume of liquid aspirated from the liquid source.

The invention relates to an ophthalmic surgical device (1) comprising: - an irrigation fluid line (4), - an aspiration fluid line (10), - at least one first fluid pump (5), - at least one second fluid pump (11), - a first flow sensor (13) coupled to the irrigation fluid line (4) for detecting a flow of the irrigation fluid in the irrigation fluid line (4), which provides a first flow signal (27), - a second flow sensor (14) coupled to the aspiration fluid line (10) for detecting a flow of the aspiration fluid in the aspiration fluid line (10), which provides a second flow signal (28), - a control unit (26) coupled with the flow sensors (13, 14) and the fluid pumps (5, 11), which is configured to provide at least a first control signal (22) for the first fluid pump (5) and a second control signal (29) for the second fluid pump (11), wherein the control unit (26) is configured to compare the first flow signal (27) with the second flow signal (28) and to provide at least the second control signal (29) at least temporarily depending on the comparison.

The present invention provides a system for automated biopsy analysis. The system includes a biopsy needle holder and delivery system configured to secure a biopsy needle, a sample transfer system configured to transfer a biopsy sample from the biopsy needle to a well of a multi-well plate, a liquid handling system configured to dispense and aspirate liquids to and from the well of the multi-well plate, an optical measurement system configured to measure fluorescent signals from the well, and a control system configured to control operations of the biopsy needle holder and delivery system, the sample transfer system, the liquid handling system, and the optical measurement system. The system enables automated processing and analysis of biopsy samples, improving efficiency and reproducibility in metabolic rate determination and other tissue analyses.

The invention relates to an ophthalmic surgical handpiece comprising: - a hollow needle designed as a cutting instrument (11), - a drive device which is designed to drive the hollow needle (1) in a predetermined direction by means of a drive (20) which can be coupled to the drive device, - an irrigation fluid pump (6) which is configured to pump irrigation fluid (3), wherein the irrigation fluid pump (6) has a first port (61) as a fluid inlet to which a first fluid line (5) is connected, wherein the first fluid line (5) is configured to be fluidically connected to an irrigation fluid reservoir (2), and a second port (62) as a fluid outlet to which a second fluid line (7) is connected, wherein the second fluid line (7) has a distal end (9) which is arranged so that the irrigation fluid (3) can flow out into a distal region (8) of the hollow needle (11), - an aspiration fluid pump (16) which is configured to pump aspiration fluid, wherein the aspiration fluid pump (16) is connected to a third fluid line (14) which is configured to receive aspiration fluid pumped by means of the hollow needle (11), and is connected to a fourth fluid line (17) which is configured to discharge the aspiration fluid into a collection container (19) at its distal end.

An ophthalmosurgical appliance includes an irrigation fluid line through which irrigation fluid can flow from an irrigation fluid container to an ophthalmosurgical handpiece for phacoemulsification, a first fluid pump configured to convey the irrigation fluid to the handpiece, a first volumetric flow determination device configured to determine a first volumetric flow, an aspiration fluid line, a second fluid pump configured to convey aspiration fluid to the collecting container, a second volumetric flow determination device configured to determine a second volumetric flow, a difference element configured to form a difference from the first volumetric flow and the second volumetric flow to form a differential volumetric flow signal, and a control device configured to determine, from the differential volumetric flow signal and the irrigation fluid setpoint pressure signal, a signal for an irrigation fluid control pressure to supply this signal at an output of the control device to the first fluid pump.

An ophthalmic surgical handpiece, comprising: a hollow needle, an irrigation fluid pump having a first port to which a first fluid line is connected, and a second port to which a second fluid line is connected, the second fluid line having a distal end arranged to allow the irrigation fluid to flow out into a distal region of the hollow needle, an aspiration fluid pump which is configured to deliver aspiration fluid, the aspiration fluid pump being connected to a third fluid line which is arranged to receive aspiration fluid conveyed with the hollow needle, and to a fourth fluid line which is arranged to discharge the aspiration fluid, and a drive device configured to drive the irrigation fluid pump, the aspiration fluid pump, and drive the hollow needle in a predetermined direction.

The present invention relates to an ophthalmic surgical system and a method for operating the same, the system comprising: a first fluid pump having a first pump chamber, a first resilient partition element, and a first drive chamber; a second fluid pump having a second pump chamber, a second elastic partition element, and a second drive chamber; a lavage fluid line and a suction fluid line; a first drive fluid line for guiding a first drive fluid to the first drive chamber; a second drive fluid line for guiding a second drive fluid to the second drive chamber; a first position sensor for detecting a first deflection position of the first elastic partition element; a second position sensor for detecting a second deflected position of the second elastic partition element; a first pressure sensor for detecting a first pressure in the first drive fluid line; a second pressure sensor for detecting a second pressure at the outlet of the first pump chamber; and / or a third pressure sensor for detecting a third pressure at the inlet of the second pump chamber; a fourth pressure sensor for detecting a fourth pressure in the second driving fluid line; a direct connection line configured to connect the irrigation fluid line to the suction fluid line; and a processing unit configured to process the first pressure, the second pressure and / or the third pressure, the fourth pressure in each case in a manner dependent on the first deflection position and the second deflection position.

The invention relates to the technical field of medical equipment, and provides an integrated gastric lavage device based on physiological information feedback, comprising: a flexible catheter integrated with multiple sensors: a miniature multi-section pressure sensor is integrated at the front end of the catheter to monitor the pressure in the stomach in real time and ensure that the pressure does not exceed a safety threshold; a near infrared spectrum sensor and a turbidity sensor are embedded in the side wall of the catheter and are respectively used for detecting the hemoglobin content and the turbidity in suction liquid; the AI visual guidance module comprises a miniature camera arranged in the head of the catheter and is used for dynamically adjusting the intubation path in combination with a pharyngeal anatomical feature recognition algorithm and responding to swallowing actions of a patient to optimize the direction of the catheter in real time. Painless intubation is realized through AI visual guidance, and discomfort and injury risks of patients are reduced; the pressure in the stomach is monitored in real time through multiple sensors, and the flow speed is intelligently regulated to guarantee safety; the closed-loop system accurately controls water quantity, ensures liquid balance, and improves safety and effectiveness of gastric lavage treatment in all directions.

The invention relates to an ophthalmic surgical apparatus (1) comprising: - an irrigation fluid line (4), - an aspiration fluid line (10), - at least one first fluid pump (5), - at least one second fluid pump (11), - a first flow sensor (13), coupled to the irrigation fluid line (4), for detecting a flow of irrigation fluid in the irrigation fluid line (4), the first flow sensor providing a first flow signal (27), - a second flow sensor (14), coupled to the aspiration fluid line (10), for detecting a flow of aspiration fluid in the aspiration fluid line (10), the second flow sensor providing a second flow signal (28), and - a control unit (26) which is coupled to the flow sensors (13, 14) and to the fluid pumps (5, 11) and is designed to provide at least one first control signal (22) for the first fluid pump (5) and one second control signal (29) for the second fluid pump (11), wherein the control unit (26) is designed to compare the first flow signal (27) with the second flow signal (28) and to provide at least the second control signal (29) at least temporarily depending on the comparison.

To provide a cleaning method and a cleaning apparatus for pre-cleaning an endoscope in which an error hardly occurs.SOLUTION: A cleaning method includes the steps of: providing an endoscope that comprises a channel system; connecting a liquid source, a suction device, and a sealing element each to a different one of the first, second, and third channel openings; and activating the suction device for drawing liquid from the liquid source towards the suction device. While drawing the liquid from the liquid source, the holding chamber volume of the liquid source is reduced by the volume of the liquid drawn from the liquid source.SELECTED DRAWING: Figure 2B

To facilitate suction of a fluid object.SOLUTION: A fluid object can be sucked from a suction nozzle 11 of a suction passage part 10 connected to a tank 20 by an ejector 60 for evacuating the inside of the tank 20. A bottle 30 is connected through a tube 40 to a suction hose 12 that is connected to the suction nozzle 11. The bottle 30 stores a cleaning liquid for improving the fluidity of the fluid object. When the suction of the fluid object is started and the pressure in the suction hose 12 is lowered, the cleaning liquid in the bottle 30 flows into the suction hose 12 through the tube 40 and mixes with the fluid object in the suction hose 12. An inflow of the cleaning liquid changes according to the pressure change in the suction hose 12.SELECTED DRAWING: Figure 1

A system that selectively controls temperature within a device such as a neck / head wrap is disclosed. The system can include a pump system having a reservoir that holds a liquid, an element that regulates temperature of the liquid within the reservoir; a pump that draws the liquid from the reservoir; and a distribution manifold attached to the pump hose that receives and distributes the liquid to at least two devices (e.g., cervical collars). The system is also equipped to be selectively monitored, for example, via a smartphone, tablet or computer.