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20 results about "Aspiration fluid" patented technology

Detection of low allele frequency mutations using allele-specific amplification and crispr / CAS13a-based method

To improve allele discrimination, the inventors adapted the system combining Cas13a detection sensitivity with allele-specific PCR amplification to propose CASPER (Cas13a Allele-Specific PCR Enzyme Recognition) as a new versatile, easy-to-implement, and highly sensitive method to detect low-frequency of sequence variant. CASPER enabled specific and sensitive detection of KRASG12D with low DNA input such as DNA extracted from patient's pancreatic ultrasound-guided fine-needle aspiration fluids. CASPER is easy to implement and a versatile reliable method virtually adaptable to any point mutation.
Owner:INST NAT DE LA SANTE & DE LA RECHERCHE MEDICALE (INSERM) +2

A cytokine flow cytometry detection kit

ActiveCN224428427UcardboardCytokine flow cytometry
This utility model belongs to the field of medical device technology, and particularly relates to a cytokine flow cytometry detection kit, including a reagent bottle and a storage box. The reagent bottle is snapped into a limiting tube. A partition plate is snapped into the inside of the storage box, and a bottle holder slot is opened on the partition plate. The bottom of the reagent bottle is inserted into the bottle holder slot. A limiting cardboard is movably set on the inner wall of the storage box. The bottom of the partition plate abuts against the bottom of the inner wall of the storage box, and the top abuts against the bottom of the limiting cardboard. In this utility model, the limiting tube can limit the pipette tip, preventing the pipette tip from falling into the reagent bottle during the process of using the pipette to draw liquid, which would prevent the operator from being unable to quickly remove the tip. The limiting cardboard can limit the top of the partition plate, preventing the partition plate from being pulled out with the bottle when the operator pulls the reagent bottle out of the bottle holder slot.
Owner:PEKING UNIV CANCER HOSPITAL INNER MONGOLIA HOSPITAL (AFFILIATED CANCER HOSPITAL OF INNER MONGOLIA MEDICAL UNIV INNER MONGOLIA AUTONOMOUS REGION CANCER HOSPITAL INNER MONGOLIA AUTONOMOUS REGION CANCER CENT)

Automated biopsy analysis system and method

A system for automated biopsy analysis is provided. The system includes a biopsy needle holder and delivery system configured to secure a biopsy needle, a sample transfer system configured to transfer a biopsy sample from the biopsy needle to a well of a multi-well plate, a liquid handling system configured to dispense and aspirate liquid to and from the well of the multi-well plate, an optical measurement system configured to measure a fluorescent signal from the well, and a control system configured to control operation of the biopsy needle holder and delivery system, the sample transfer system, the liquid handling system, and the optical measurement system. The system enables automated processing and analysis of biopsy samples, improving efficiency and reproducibility of metabolic rate determination and other tissue analysis.
Owner:EFANI AGRICULTURAL CO

Drainage device for care and monitoring

Drainage device, comprising a vacuum pump (1), a suction line (2) connected to this vacuum pump (1), a gas-tight liquid collection container (6) which is connected to the suction line (2) and serves to reliably maintain the negative pressure and to collect extracted liquid, a suction pipe (5) which is connected to a rear area of ​​a hollow cover element (3) which is open at its front and which opens into the liquid collection container (6) at its end facing away from the cover element (3), characterized by the fact that the cover element (3) has a sponge pad (4) at its front opening, wherein the sponge pad (4) absorbs fluid from the wound area and distributes a negative pressure evenly, wherein the negative pressure generated by the vacuum pump (1) via the suction line (2) first reaches the fluid collection container (6) and from there is directed via the suction tube (5) to the cover element (3) and further to the sponge pad (4), while the fluid absorbed from the wound area is transported via the sponge pad (4) and through the suction tube (5) into the fluid collection container (6).
Owner:GUANGDONG PHARMACEUTICAL UNIVERSITY GUANGDONG PROVINCE

Negative pressure suction gun, manual negative pressure suction method

The application discloses a kind of negative pressure suction gun, manual negative pressure suction method, it is related to biomedical engineering technical field, the gun handle of negative pressure suction gun is reciprocated and opened and closed to drive suction pumping section to reciprocate in negative pressure sedimentation cavity Negative pressure suction and extrusion pumping, negative pressure sedimentation cavity can pass through liquid suction pipe one-way liquid suction when negative pressure suction, negative pressure sedimentation cavity can be one-way liquid delivery to the liquid storage part when extrusion pumping, so as to be used for suction liquid and soft solid tissue in liquid by setting negative pressure sedimentation cavity, then by adjusting increase negative pressure suction force, the viscosity of solid tissue that can be sucked is also greater, so that the negative pressure suction gun of the application can not only be used for endometrial gynecological field liquid suction and solid tissue sampling, but also can be used for closed narrow space tumor biopsy, brain tissue and other solid-liquid components suction, during suction process, by rotating liquid suction pipe, the inlet slope of liquid suction pipe is realized 360 degree rotation, to avoid suction dead angle.
Owner:SHENZHEN MATERNITY & CHILD HEALTHCARE HOSPITAL

Special-shaped multi-cavity visual bending-adjustable multi-parameter monitoring cavity device

The invention belongs to the technical field of medical apparatus and instruments, and particularly relates to a special-shaped multi-cavity visual bending-adjustable multi-parameter monitoring cavity device. The device is composed of an operation unit, a bundling pipe and a bending adjusting unit, the bundling pipe is inserted into a cavity channel for cleaning, suction, endoscopy and the like, the bending adjusting unit can check all angles in the cavity channel, and the operation unit controls the turning angle of the bending adjusting unit and liquid suction of the bundling pipe; the functions of the operation unit are optimized and enhanced, the clinical application range of the device is expanded, the device is complete in function and convenient and fast to operate, a clear and visual diagnosis and treatment means for lesions in the cavity is provided for medical staff, the scientificity, safety, convenience, high efficiency, intelligent characteristics and operation accuracy of the device remarkably improve the medical work efficiency, and the clinical application range of the device is widened. And a more accurate and safer diagnosis and treatment service is provided for the patient.
Owner:谭黎明

A tube sealing apparatus

The application discloses a flushing and sealing pipe device in the technical field of medical auxiliary devices, which comprises a liquid supply component, a driving pump and a hose. The liquid supply component is installed on the pump shell of the driving pump, which improves the integration of the flushing and sealing pipe device and makes the flushing and sealing pipe device convenient to store or carry. The two ends of the hose are respectively connected with the liquid supply component and the intravenous catheter, and the middle part of the hose is arranged in the interior of the pump shell, so that the hose does not need to be disconnected with the intravenous catheter for multiple times for sucking liquid, the number of interface exposure is significantly reduced, and the risk of intravenous catheter pollution is significantly reduced. The rotary pump head in the interior of the pump shell extrudes the hose, so that the liquid in the liquid supply component flows to the intravenous catheter to flush and seal the pipe. The steps of sucking, disinfecting, exhausting, bolus injection and the like are omitted, the flushing and sealing pipe operation is more convenient and fast, the artificial operation time is reduced, and the threshold of the flushing and sealing pipe operation is lowered.
Owner:HAOLANG TECH (FOSHAN) LTD CO

Ophthalmic surgical system and method for operating the ophthalmic surgical system

An ophthalmic surgical system includes: a first position sensor for detecting a first deflection position of the first elastic partition element, a second position sensor for detecting a second deflection position of the second elastic partition element, a first pressure sensor for detecting a first pressure in a first drive fluid line, a second pressure sensor for detecting a second pressure at an outlet of a first pump chamber and / or a third pressure sensor for detecting a third pressure at an inlet of a second pump chamber, a fourth pressure sensor for detecting a fourth pressure in the second drive fluid line, a direct connection line configured to connect the irrigation fluid line to the aspiration fluid line, a processing unit for processing the first pressure, the second pressure and / or the third pressure, the fourth pressure, in each case dependent on the first and the second deflection position.
Owner:CARL ZEISS MEDITEC AG

Ophthalmic Surgery Unit

The invention relates to an ophthalmic surgical device (1) comprising: - an irrigation fluid line (4), - an aspiration fluid line (10), - at least one first fluid pump (5), - at least one second fluid pump (11), - a first flow sensor (13) coupled to the irrigation fluid line (4) for detecting a flow of the irrigation fluid in the irrigation fluid line (4), which provides a first flow signal (27), - a second flow sensor (14) coupled to the aspiration fluid line (10) for detecting a flow of the aspiration fluid in the aspiration fluid line (10), which provides a second flow signal (28), - a control unit (26) coupled with the flow sensors (13, 14) and the fluid pumps (5, 11), which is configured to provide at least a first control signal (22) for the first fluid pump (5) and a second control signal (29) for the second fluid pump (11), wherein the control unit (26) is configured to compare the first flow signal (27) with the second flow signal (28) and to provide at least the second control signal (29) at least temporarily depending on the comparison.
Owner:CARL ZEISS MEDITEC AG

Ophthalmosurgical appliance

ActiveUS12611328B2Eye surgeryHydrologyPhacoemulsification
An ophthalmosurgical appliance includes an irrigation fluid line through which irrigation fluid can flow from an irrigation fluid container to an ophthalmosurgical handpiece for phacoemulsification, a first fluid pump configured to convey the irrigation fluid to the handpiece, a first volumetric flow determination device configured to determine a first volumetric flow, an aspiration fluid line, a second fluid pump configured to convey aspiration fluid to the collecting container, a second volumetric flow determination device configured to determine a second volumetric flow, a difference element configured to form a difference from the first volumetric flow and the second volumetric flow to form a differential volumetric flow signal, and a control device configured to determine, from the differential volumetric flow signal and the irrigation fluid setpoint pressure signal, a signal for an irrigation fluid control pressure to supply this signal at an output of the control device to the first fluid pump.
Owner:CARL ZEISS MEDITEC AG

Integrated gastric lavage equipment based on physiological information feedback and control system thereof

The invention relates to the technical field of medical equipment, and provides an integrated gastric lavage device based on physiological information feedback, comprising: a flexible catheter integrated with multiple sensors: a miniature multi-section pressure sensor is integrated at the front end of the catheter to monitor the pressure in the stomach in real time and ensure that the pressure does not exceed a safety threshold; a near infrared spectrum sensor and a turbidity sensor are embedded in the side wall of the catheter and are respectively used for detecting the hemoglobin content and the turbidity in suction liquid; the AI visual guidance module comprises a miniature camera arranged in the head of the catheter and is used for dynamically adjusting the intubation path in combination with a pharyngeal anatomical feature recognition algorithm and responding to swallowing actions of a patient to optimize the direction of the catheter in real time. Painless intubation is realized through AI visual guidance, and discomfort and injury risks of patients are reduced; the pressure in the stomach is monitored in real time through multiple sensors, and the flow speed is intelligently regulated to guarantee safety; the closed-loop system accurately controls water quantity, ensures liquid balance, and improves safety and effectiveness of gastric lavage treatment in all directions.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Ophthalmic surgical apparatus

The invention relates to an ophthalmic surgical apparatus (1) comprising: - an irrigation fluid line (4), - an aspiration fluid line (10), - at least one first fluid pump (5), - at least one second fluid pump (11), - a first flow sensor (13), coupled to the irrigation fluid line (4), for detecting a flow of irrigation fluid in the irrigation fluid line (4), the first flow sensor providing a first flow signal (27), - a second flow sensor (14), coupled to the aspiration fluid line (10), for detecting a flow of aspiration fluid in the aspiration fluid line (10), the second flow sensor providing a second flow signal (28), and - a control unit (26) which is coupled to the flow sensors (13, 14) and to the fluid pumps (5, 11) and is designed to provide at least one first control signal (22) for the first fluid pump (5) and one second control signal (29) for the second fluid pump (11), wherein the control unit (26) is designed to compare the first flow signal (27) with the second flow signal (28) and to provide at least the second control signal (29) at least temporarily depending on the comparison.
Owner:CARL ZEISS MEDITEC AG

Temperature regulating pump system and attachment mechanisms thereof

A system that selectively controls temperature within a device such as a neck / head wrap is disclosed. The system can include a pump system having a reservoir that holds a liquid, an element that regulates temperature of the liquid within the reservoir; a pump that draws the liquid from the reservoir; and a distribution manifold attached to the pump hose that receives and distributes the liquid to at least two devices (e.g., cervical collars). The system is also equipped to be selectively monitored, for example, via a smartphone, tablet or computer.
Owner:NEURORESCUE INC

Pipe punching and sealing equipment

The invention discloses pipe flushing and sealing equipment in the technical field of medical auxiliary instruments. The pipe flushing and sealing equipment comprises a liquid supply component, a driving pump and a hose. And the liquid supply component is mounted on the pump shell of the driving pump, so that the integration level of the flushing and sealing pipe equipment is improved, and the flushing and sealing pipe equipment is convenient to store or carry. The two ends of the hose are communicated with the liquid supply component and the venous catheter respectively, the middle of the hose penetrates into the pump shell, the hose does not need to be disconnected from the venous catheter for sucking liquid repeatedly, the number of exposure times of a connector is remarkably reduced, and the risk of pollution to the venous catheter is remarkably reduced. The rotary pump head in the pump shell extrudes the hose, so that liquid in the liquid supply component flows to the venous catheter, and the catheter is flushed and sealed. The links of suction, disinfection, exhaust, injection and the like are omitted, so that the tube flushing and sealing operation is simpler, more convenient and quicker, the manual operation time is shortened, and the threshold of the tube flushing and sealing operation is lowered.
Owner:HAOLANG TECH (FOSHAN) LTD CO

Catheter simulator and pulsatile flow generation method

Provided is a catheter simulator capable of reproducing, in a heart model held in a liquid in a container, a blood flow and cardiac pulsations in a living body. The catheter simulator comprises: a container 10 filled with a liquid; an elastic heart model 100 which is installed in the container 10 in a state of being filled with the liquid and in which a ventricle and a large blood vessel continuous with the ventricle are provided; and a pulsation pump 50 which is connected to the large blood vessel of the heart model 100 or is connected a space continuous with the large blood vessel, and which generates negative pressure in the ventricle by suctioning the liquid.
Owner:OSAKA UNIVERSITY +1

A device for applying a medicated ointment to a lupus erythematosus lesion

PendingCN122297889AWarm waterLiquid tank
This invention discloses a device for applying ointment to lupus erythematosus lesions, including a connecting rod. A cleaning component is located at one end of the connecting rod. The cleaning component includes a fixed plate fixedly connected to one end of the connecting rod, a nozzle on one side of the fixed plate, and a placement groove on the side wall of the connecting rod. A liquid tank is placed in the placement groove. The input end of the nozzle is connected to the output end of a transfer pipe connected to one end of the liquid tank. The nozzle can switch between multiple water output modes. A fixing component is located between the liquid tank and the connecting rod. The cleaning component in this invention can pre-clean the patient's lesions with warm water before applying ointment, thereby reducing irritation to the lesion during ointment application. When using the cleaning component, clean warm water is first poured into the liquid tank, and then the liquid tank is placed into the placement groove in the connecting rod. At this time, a drive pump located in the connecting rod can draw warm water from the liquid tank and simultaneously pump the water into the nozzle located on one side of the fixed plate.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

Injection device for swallowing balloon dilation training

1. The name of the design product: injection device for swallowing balloon dilation training. 2. The use of the design product: for injecting or pumping liquid in the swallowing balloon dilation training rehabilitation treatment for patients with swallowing dysfunction. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: front view.
Owner:HULUNBEIER CHINA MONGOLIA HOSPITAL (HULUNBEIER CHINA MONGOLIA MEDICAL RES INST)

Ophthalmic surgical handpiece and ophthalmic surgical system comprising such handpiece

An ophthalmic surgical handpiece comprising: a hollow needle; an irrigation fluid pump having a first port to which a first fluid line is connected and a second port to which a second fluid line is connected, the second fluid line having a distal end arranged to allow irrigation fluid to flow into a distal region of the hollow needle; an aspiration fluid pump configured to deliver aspiration fluid, the aspiration fluid pump being connected to a third fluid line, the third fluid line being arranged to receive aspiration fluid delivered with the hollow needle, and the aspiration fluid pump being connected to a fourth fluid line, the fourth fluid line being arranged to discharge aspiration fluid; and a drive device configured to drive the lavage fluid pump, the aspiration fluid pump, and the hollow needle in a predetermined direction.
Owner:CARL ZEISS MEDITEC CATARACT TECH INC

Ophthalmic surgical handpiece and ophthalmic surgical system comprising such a handpiece

PendingUS20260191684A1Drive shaftReoperative surgery
An ophthalmic surgical handpiece includes a hollow needle, an irrigation fluid pump having a first port as a fluid inlet and a second port as a fluid outlet, an aspiration fluid pump configured to deliver aspiration fluid, the aspiration fluid pump being connected to a fluid line which is arranged to receive aspiration fluid conveyed with the hollow needle, and to a fluid line which is arranged to discharge the aspiration fluid at its distal end into a collection container, and a drive device including a drive shaft and a gear, wherein the drive shaft is configured to drive the irrigation fluid pump and the aspiration fluid pump together with a drive apparatus which is configured to be coupled to the drive device, and wherein the drive shaft is configured to drive the hollow needle in a predetermined direction with the gear.
Owner:CARL ZEISS MEDITEC CATARACT TECH INC