Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

77 results about "Nasal pharynx" patented technology

Intelligent classification and identification method for ear-nose-throat lesion images

The invention discloses an intelligent classification and recognition method for ear-nose-throat lesion images, and relates to the technical field of image recognition, and the method comprises the steps: synchronously collecting a nasopharynx white light image and an i-Scan image, screening an image meeting a quality standard, carrying out the correlation of pathology and grading labeling, and constructing a data set containing a multi-center case; the white light image and the i-Scan image are subjected to denoising processing, key mark points are extracted, image registration is completed, a mucous membrane surface area, a submucous membrane blood vessel area and a lymphatic tissue enrichment area are divided through semantic segmentation, and feature enhancement is carried out on different areas; extracting morphological features and textural features from the enhanced image, calculating feature importance weights and fusing the feature importance weights into low-dimensional feature vectors; the benign and malignant dichotomy model and the pathological type multi-classification model are respectively constructed, and classification results are output in combination with a doctor diagnosis rule base and verification indexes, so that the accuracy and clinical practicability of ear-nose-throat lesion diagnosis are remarkably improved.
Owner:SHANGHAI PUTUO DISTRICT CENT HOSPITAL

Catheter for recovery of dysphagia

Devices and methods for assisting a patient with recovery from dysphagia are disclosed herein. In some embodiments, the device comprises a catheter with sections whose curvatures correspond to curves between external nares of the patient and a nasal cavity and between the nasal cavity and a nasopharynx. The device may further include an electrode at a distal portion of the catheter and configured to deliver stimulation energy to nearby tissue.
Owner:PHAGENESIS LTD

Pharynx aspiration device for minimizing infectious particle exposure during endonasal surgeries

A method for minimizing infectious particle exposure during endonasal surgeries includes the steps of: introducing an aspiration device through a mouth of a patient and positioning a distal tip within the nasopharynx space, the aspiration device comprising an elongated balloon catheter having an inflatable balloon located within a distal region thereof and a distal aspiration port that is positioned distal to the balloon; inflating the balloon so that the balloon occupies the nasopharynx space; and aspirating any infectious particles within the nasopharynx space via the distal aspiration port.
Owner:MT SINAI SCHOOL OF MEDICINE

Nasopharyngolaryngoscope

ActiveCN309400165SLarynxNose
1. Name of the design product: Nasopharyngolaryngoscope. 2. Use of the design product: For medical units to conduct examinations and treatments on the mouth, nose, pharynx, and larynx in clinical practice, and to be used in conjunction with equipment such as electronic endoscope image processors. 3. Design key points of the design product: Lies in the shape. 4. Picture or photo that best shows the design key points: Perspective view 1.
Owner:MACROLUX MEDICAL TECH CO LTD

Nasal tracheal catheter and nasopharyngeal cavity three-dimensional sensing method

The invention provides a nasal tracheal catheter and a nasopharyngeal cavity three-dimensional sensing method. The method comprises the following steps: generating a geometric three-dimensional surface model of a nasopharyngeal cavity; associating pressure information of the outer wall of the front end of the catheter to a nearest coordinate point area on the geometric three-dimensional surface model, and marking on the geometric three-dimensional surface model through a preset threshold value to obtain a plurality of high-pressure contact points; determining the extension strength in the surface normal direction of the geometric three-dimensional surface model by taking each high-voltage contact point as the center; performing curved surface reconstruction on all the high-voltage contact points based on the extension strengths corresponding to different high-voltage contact points to obtain a safety boundary curved surface enveloped outside the geometric three-dimensional surface model; and performing spatial position judgment on a short-term predicted movement track of the catheter and the safe boundary curved surface, and generating a three-dimensional sensing path of the catheter in a safe passing area in the nasopharyngeal cavity according to a judgment result. By the adoption of the scheme, three-dimensional spatial perception of interaction force between the catheter and nasopharyngeal cavity tissue can be achieved.
Owner:宿颖岚

Nasogastric tube based on synergistic resistance reduction and lubrication of micro-nano texture and antibacterial hydrogel

The invention belongs to the technical field of medical materials, and provides a nasogastric tube based on synergistic resistance reduction and lubrication of a micro-nano texture and antibacterial hydrogel, and the nasogastric tube comprises an anti-friction resistance-reducing surface with a micro-nano structure and a hydrophilic antibacterial hydrogel coating. A traditional nasogastric tube is mostly made of polymer materials such as polydimethylsiloxane, the hydrophobic surface of the traditional nasogastric tube is prone to generating large insertion resistance in the intubation process, and discomfort and pain of nasopharynx and esophagus and even inflammation infection are brought to a patient. The resistance in the insertion process is remarkably reduced by combining the hydrophilic hydrogel pattern layer, so that the wettability is enhanced, the smoothness during insertion and extraction is improved, and the mechanical stimulation to the nasal cavity and throat tissues is reduced. The hydrophilic antibacterial hydrogel coating is coated on the surface of the nasogastric tube, so that the structural design not only improves the comfort of a patient in the use process, but also endows the tube body with certain antifouling and antibacterial properties, and reduces the risk of occurrence of discomfort related to bacterial infection and friction.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY

Nutrition tube and nutrition tube system

The utility model provides a nutrient canal and a nutrient canal system, and relates to the technical field of medical instruments. The nutrient canal comprises a canal body and a canal joint, the canal joint is provided with a first connecting end, a clamping groove is formed in the hole wall of an inner hole of the first connecting end, the canal body is provided with a second connecting end, the second connecting end is provided with a clamping tongue, and the height, protruding out of the canal body, of the clamping tongue is gradually increased or gradually increased and then decreased in the direction away from the end of the second connecting end; the second connecting end can be arranged in the inner hole in a penetrating mode so that the clamping tongue can be connected with the clamping groove in a clamping mode. In the process of inserting the nutrition tube, the tube connector and the tube body are separated firstly, the tube body enters the instrument from the oral cavity and is inserted, after in-vivo indwelling of the tube body is completed, the second connecting end is drawn out from the nasopharynx from the oropharynx at the soft palate, and then the second connecting end of the tube body and the first connecting end of the tube connector are connected in a clamped mode. Obviously, due to the design of the clamping tongue, the outer diameter of the second connecting end is reduced, and stimulation to a patient can be reduced.
Owner:SHENZHEN CONCEMED MEDICAL TECHNOLOGY CO LTD +1

Multifunctional bedside nasojejunum nutrition tube placement training device

The utility model discloses a multifunctional bedside nasojejunum nutrition tube placement training device which comprises a head and neck bionic block, a nasopharyngeal cavity channel is arranged in the head and neck bionic block; the pleuroperitoneal cavity frame comprises a hard simulation frame and bionic skin covering the hard simulation frame. Wherein the head and neck bionic block and the pleuroperitoneal cavity frame are integrally formed or detachably connected. A bionic esophagus, a bionic stomach, a bionic duodenum and a part of bionic jejunum which are sequentially connected are arranged in the pleuroperitoneal cavity frame, and a bionic cardia and a bionic pylorus are arranged at the head end and the tail end of the bionic stomach respectively. A bionic inferior vena cava, a bionic abdominal aorta, a bionic mesenteric superior vein and a bionic mesenteric superior artery are further arranged in the pleuroperitoneal cavity frame; the bionic inferior vena cava and the bionic abdominal aorta are arranged on the rear sides of the bionic stomach and the bionic duodenum, the bottom ends are closed, and the head ends penetrate out of the bionic skin; the bottom ends of the bionic superior mesenteric vein and the bionic superior mesenteric artery are closed, and the head ends of the bionic superior mesenteric vein and the bionic superior mesenteric artery partially wrap the bionic duodenum and then penetrate out of the bionic skin.
Owner:THE FIRST AFFILIATED HOSPITAL OF NAVAL MEDICAL UNIVERSITY OF CHINESE PEOPLES LIBERATION ARMY

Small animal model for skull base high-flow cerebrospinal fluid leakage and skull base reconstruction, construction method and application

PendingCN121845787AOvercoming the technical barrier of inability to reach the middle skull base via the noseSurgical veterinaryAnterior skull basePalate muscle
The invention belongs to the technical field of medical experimental animal models, and discloses a small animal model for skull base high-flow cerebrospinal fluid leakage and skull base reconstruction as well as a construction method and application of the small animal model. The technical obstacle that due to the fact that the nasal cavity of a small animal is narrow and the turbinate structure is complex, surgical instruments cannot reach the skull base through the nose is overcome, meanwhile, a modeling and repairing area is arranged on the rear nasal meatus and the top wall of the nasopharynx, and the temperature and humidity conditions and environment of the nasal mucosa are reserved; and the microenvironment for tissue healing after the endoscopic transnasal skull base surgery is restored on the pathophysiological level. The dissected marking points are clear, and compared with narrow anterior skull base low-flow cerebrospinal fluid leakage of small animals, the standardized bone defect constructed in the middle skull base butterfly saddle area can cause continuous and high-flow cerebrospinal fluid leakage; autologous bone flap and free mucous membrane repair is used, the method is the same as current clinical practice, and a new platform can be provided for screening of skull base repair materials or operation evaluation and retrograde intracranial infection research after an operation.
Owner:THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

A device for measuring inhalation pressure in the nasopharynx in order to determine the position of the tongue by measuring the negative pressure in the oral cavity, and an associated terminal.

ActiveJP7911355B2InhalationDentistry
The present invention relates to a device for determining tongue position from measurement of intraoral vacuum pressure generated by swallowing, the device comprising an intraoral screen intended to be placed in the oral cavity, a conduit connectable at a first end to the intraoral screen and at a second end to a manometer, which is in turn connectable to a base, and an electronic module connectable to the base, the electronic module being in data communication with the manometer and including a processing unit, such that in an operative state of the device, the intraoral screen is configured to shield interdental spaces in the oral cavity, and the conduit establishes fluid communication between the interior of the oral cavity and the manometer, whereby negative pressure generated by swallowing is measured by said manometer.
Owner:カーンサンドラ ヴィヴィアン +1

Multifunctional nasopharynx medical device

The invention relates to the technical field of nasal irrigation equipment, and discloses a multifunctional nasopharynx medical device which comprises a device body, a function auxiliary cavity and an external driving motor, the bottom of the device body is connected with the function auxiliary cavity in a lap joint mode, and an embedded cavity is connected into the function auxiliary cavity in an embedded mode. A fixed mounting plate is fixedly connected to the middle part of one side of the interior of the embedded cavity, the embedded cavity is used for fixedly arranging the fixed mounting plate, stably supporting and fixing a folding telescopic rod and fixedly connecting a water receiving cavity, and the folding telescopic rod has a flexible and convenient telescopic effect; a water receiving cavity is directly embedded into an embedding cavity for storage and storage, a guide connecting rod carries out electric disinfection support on disinfection equipment and an ultraviolet disinfection lamp at the bottom, internal flushing water is effectively disinfected, a filter screen and a pressing air bag are arranged on one side of the interior of a water storage cavity for flowing of water flow, and the water storage cavity is internally provided with a water inlet and a water outlet. And the water outlet is controlled by using a surface lap joint valve.
Owner:陈灼

Adenoid stent and adenoid support assembly

The present disclosure relates to an adenoid stent and an adenoid support assembly. The adenoid stent includes: a tubular support portion for supporting in the nasal passage; a first expansion support portion for supporting at the anterior nostril, the first expansion support portion being provided at the first end of the tubular support portion and expanding radially outward relative to the tubular support portion; and a second expansion support portion for pressing the adenoid against the posterior wall of the nasopharynx, the second expansion support portion being provided at the second end of the tubular support portion opposite to the first end and expanding radially outward relative to the tubular support portion; wherein the first expansion support portion, the second expansion support portion and the tubular support portion are coaxially arranged, and the first expansion support portion, the second expansion support portion and the tubular support portion are configured as a mesh structure capable of radially telescoping. Through the above technical solution, the adenoid stent and the adenoid support assembly provided by the present disclosure can solve the technical problem of being unable to balance the support of the adenoid and the ventilation of the nasal airway.
Owner:NANJING YOUWEI MEDICAL TECH CO LTD

Mouth-nose combined multi-arm nasopharynx skull base surgical robot

ActiveCN121101761ASurgical robotsArmsNoseSkull base surgery
The invention provides a mouth-nose combined multi-arm nasopharynx skull base surgical robot, and relates to the technical field of nasopharynx skull base surgeries, the mouth-nose combined multi-arm nasopharynx skull base surgical robot comprises a mounting plate, a first surgical arm and a second surgical arm are arranged on the mounting plate, a first positioning integration and a second positioning integration are integrated in the first surgical arm, a third positioning integration is integrated in the second surgical arm, and the first positioning integration and the second positioning integration are integrated in the mounting plate. The first positioning integration, the second positioning integration and the third positioning integration are each internally provided with an upper arc-shaped plate. According to the device, the auxiliary knife arm, the lens arm and the main knife arm are arranged, the auxiliary knife arm and the lens arm can enter from the nasal cavity, the main knife arm can enter from the oral cavity, the design can better cope with a bent approach and an operation scene requiring complex operation, an operation area can be observed and operated from multiple angles, a clear visual field is provided, and the operation efficiency is improved. A doctor can more accurately judge the relation between the lesion position and surrounding tissue, and the problems caused by the leverage effect of a rigid straight sheath in a traditional natural orifice surgical robot are solved.
Owner:SUN YAT SEN UNIV

Auxiliary nasopharynx swab sampling device

The nasopharynx swab sampling auxiliary device comprises a base, a chair, a pushing mechanism, a jaw jacking mechanism and a sampling mechanism, through the combination of the chair and the pushing mechanism, the distance between the top jaw mechanism and the chair and the distance between the sampling mechanism and the chair are flexibly adjusted, and a patient can conveniently enter and exit from the chair; the jaw jacking mechanism jacks the lower jaw of a patient from bottom to top through stretching and retracting of the first supporting rod, the patient is assisted in keeping the posture that the head leans backwards, and nasopharynx swab sampling operation can be conducted smoothly. The operation of sampling the nasopharynx swab is realized by the sampling mechanism; the driving part A drives the whole poking mechanism to rotate, so that the swab rod can be quickly adjusted to be in an inclined upward direction and an inclined downward direction to respectively meet the sampling requirements of a nose swab and a throat swab; the method can be realized without different complex structures; according to the poking mechanism, the swab rod can be rapidly disassembled, rapidly installed and clamped through the cooperation of the clamping screw tube and the screwing nut, and medical staff do not need to hold the swab rod by hand for operation.
Owner:YIWU CENT HOSPITAL (YIWU CENT HOSPITAL MEDICAL COMMUNITY)

Visual nasal tracheal catheter

ActiveCN223861136UTracheal tubesEndoscopesNasopharyngeal catheterNasal Cavity Epithelium
The visual nasal tracheal catheter comprises a catheter body, the air inlet end of the catheter body is connected with a breathing machine connector, and the air outlet end of the catheter body is provided with an arc-shaped insertion part. Air vents are formed in two sides of the insertion part to form an arch-bridge-shaped front end, and a camera assembly is arranged at the arch-bridge-shaped front end; a first air bag is arranged on the catheter body close to the air outlet end; a second air bag is arranged in the middle section of the catheter body; a bending structure is arranged at the end, close to the breathing machine connector, of the catheter body. The two sides of the insertion part at the front end of the visible nasal tracheal catheter are provided with the air vents, the top end of the visible nasal tracheal catheter forms the arch-bridge-shaped front end, and when the ventilation catheter is inserted into a nasal cavity, the arch-bridge-shaped front end serves as the foremost end to make contact with the nasal cavity and cannot scratch nasal mucosa; the camera assembly is arranged at the front end of the arch bridge shape, visualization of the nasopharyngeal catheter insertion process is achieved, and therefore damage to nasal mucosa in the insertion process is effectively reduced or avoided, and the one-time insertion success rate of the nasotracheal catheter is remarkably increased.
Owner:MIBON (SHANDONG) MEDICAL TECHNOLOGY CO LTD

Oral and nasopharyngeal airway

ActiveCN223183880UTracheal tubesNasopharyngeal airwayOxygen supply
The utility model provides a mouth and nasopharynx airway which comprises a ventilation supporting tube and a mouth bite with a cavity, and the ventilation supporting tube is temporarily embedded and fixed in the mouth bite with the cavity. The whole body can be used as an oropharyngeal airway, and the ventilation supporting tube can be taken out from the mouth bite with the cavity and can be used as a nasopharyngeal airway; the ventilation supporting tube is provided with the respiration monitoring cavity and the oxygen supply cavity, can be connected with oxygen for inhalation during use, is connected with a carbon dioxide monitor for end-tidal carbon dioxide monitoring, and is simple in structure, low in cost, safe and reliable.
Owner:WUXI PEOPLES HOSPITAL +1

Nasopharynx washing and nursing device for oncology department

The nasopharynx washing and nursing device comprises a mounting frame, and a rotating disc is rotationally arranged at the top of the mounting frame through a bearing; the water collecting hopper is fixed at the top of the turntable through a first connecting pipe and is used for collecting flushing wastewater; the sewage tank is matched with the piston tube through the driving mechanism, so that an intermittent flushing mode can be realized, the cleaning fluid is intermittently pushed to the nasal cavity by utilizing the reciprocating pushing assembly, a continuous flushing mode can also be switched, the first piston rod is driven to rotate through the transmission assembly to continuously extrude the cleaning fluid, and different flushing requirements are met; a rotating disc is arranged to adjust the position of a fixing pipe, nasal cavities on the two sides can be conveniently cleaned, precise positioning is achieved through cooperation of a pin column and a positioning groove, a cleaning mechanism is arranged, the used spray head can be cleaned and disinfected in the flushing process, dirt on the surface of the spray head is effectively removed through boiling water flushing and rotation of a brush in a cleaning cup, and the cleaning effect is good. Hygiene and safety in the flushing process are guaranteed, and convenience and guarantee are provided for nasopharynx flushing nursing.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

A nasopharyngeal tumor radiotherapy flushing device

ActiveCN224540583UNasal cavityNasopharyngeal tumors
The utility model provides a nasopharyngeal tumor radiotherapy flushing device belongs to medical instrument technical field. Including liquid storage bottle, the two sides of liquid storage bottle are equipped with the holding area, the bottom fixed connection of liquid storage bottle has the connecting pipe, the top of liquid storage bottle is connected with the flushing pipe threadedly, adjusting assembly, adjusting assembly is used for changing the area of liquid medicine flushing, adjusting assembly is connected with the flushing pipe, prevent backflow assembly, prevent backflow assembly is used for preventing the water backflow after flushing, prevent backflow assembly is connected with liquid storage bottle, can change the flushing area through setting adjusting assembly, utilize the initial state of shower nozzle to carry out the flushing in the inside of nasal cavity, through the rotation sealing sleeve, the shower nozzle extends upward, and the spout opens, realizes the overall flushing to the four around of nasal cavity, ensures that there is no flushing dead angle. When encountering blood scab and other difficult cleaning material, still can pass through the reverse rotation sealing sleeve, enhances the water pressure of shower nozzle port, promotes the cleaning effect.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY

Oral and nasal tracheal intubation assistance device

ActiveUS12599738B1Tracheal tubesMedical devicesNasotracheal intubationEndotracheal tube
An oral and nasal tracheal intubation assistance device for assisting in endotracheal intubation includes an esophageal plug portion and a ramped guidance portion. The oral and nasal tracheal intubation assistance device temporarily occludes the esophageal inlet while providing a guided pathway for endotracheal tube placement into the trachea. The oral and nasal tracheal intubation assistance device includes a handle with an ergonomic grip oriented perpendicular to the body via a curved transition portion. Two primary embodiments are disclosed: an oral version for orotracheal intubation and a nasal version for nasotracheal intubation. The ramped guidance portion includes a capture segment and a guidance segment that work in concert to redirect and guide the endotracheal tube toward the tracheal inlet. The oral and nasal tracheal intubation assistance device provides a standardized approach to both oral and nasal intubation procedures while improving first-pass success rates.
Owner:STRAMIELLO JOSHUA ANTHONY

Disposable nasopharyngeal airway

ActiveCN223874226UTracheal tubesNasal cavityNasopharyngeal airway
The utility model relates to the technical field of medical instruments, and discloses a disposable nasopharyngeal airway which comprises an airway body, a first air vent is arranged at the left end of the airway body, a second air vent is arranged at the right end of the airway body, and a soft rubber block is arranged on the outer wall of the left end of the airway body. According to the nasopharyngeal airway, one end of the first ventilation opening of the airway body is inserted into the nasal cavity of a patient, the nose wing of the patient can be clamped between the connecting rod and the airway body, the effect of stably fixing the nasopharyngeal airway is achieved, the soft rubber block is arranged at the first ventilation opening, the discomfort of the patient is reduced, and the situation that the patient moves randomly is avoided; the discomfort of the patient is reduced, and the comfort of the patient is enhanced.
Owner:HANGZHOU TRIFANZ MEDICAL DEVICE CO LTD

Infrared nasal allergy patch for adjuvant therapy of rhinitis and preparation method of infrared nasal allergy patch

The invention belongs to the technical field of biological medicines, and particularly relates to an infrared nasal allergy patch for adjuvant therapy of rhinitis and a preparation method thereof. Different traditional Chinese medicines such as the astragalus membranaceus, the ephedra, the cocklebur fruit, the echinacea, the lupin and the ceratocarpus lingnanensis are specifically combined, so that mutual cooperation of the traditional Chinese medicines is facilitated; after the traditional Chinese medicine composition is combined with the medical stone powder and the ceramic powder, the traditional Chinese medicine composition acts on the disease site of rhinitis through multiple targets; therefore, the nasal allergy patch provided by the invention has the effects of improving blood circulation, relieving pain, increasing muscle relaxation and improving the immunity of the organism, is not only beneficial to adjuvant therapy of rhinitis and relieving symptoms such as rhinorrhea, sneezing, nasal obstruction, rhinocnesmus, throat itching and nasopharynx discomfort, and has a good effect.
Owner:GUANGZHOU YUEHUA MEDICAL TECH CO LTD

Device for determining the position of the tongue by measuring the negative pressure in the oral cavity, device for measuring the suction pressure in the nasopharyngeal cavity and external terminal

ActiveCN116940314BCatheterDentistry
The invention relates to a device for determining the position of the tongue by measuring the vacuum pressure in the mouth resulting from swallowing, comprising an intraoral septum arranged in the mouth, a catheter connected at one end to the intraoral septum and at the other end to a pressure gauge arranged to a base, and an electronic module cooperating with the base. The electronic module is in data communication connection with the pressure gauge, the electronic module comprising a processing unit such that, in the operating conditions of the device, the intraoral septum is configured to obstruct the interdental spaces in the mouth and the catheter establishes communication between the inside of the mouth and the pressure gauge, so that the negative pressure resulting from swallowing is measured by the pressure gauge.
Owner:桑德拉·薇薇安·卡恩 +1

Nasopharyngeal adenoid collector

The invention discloses a nasopharyngeal adenoid collector. The nasopharyngeal adenoid collector comprises an inner-layer sampling structure, a middle-layer sampling structure and an outer-layer protection structure. The inner-layer sampling structure comprises a metal wire, a base and a brush sampling head. The middle-layer sampling structure comprises a metal tube, a middle-layer tube seat and a net bag sampling structure. And the outer-layer protection structure comprises an outer-layer tube seat and a sheath tube. In a use state, the middle-layer tube seat is rotated to be clamped on the outer-layer tube seat, the driving structure arranged between the middle-layer tube seat and the outer-layer tube seat is extruded by pressing the base, so that the brush sampling head and the net bag sampling structure are popped up, and the base is rotated to be clamped on the outer-layer tube seat. The base is rotated, so that the brush sampling head and the net bag sampling structure are used for sampling. According to the embodiment, the sampling steps can be simplified, the sampling time is shortened, the situation that the sample is polluted in the nasal cavity and the sample is polluted in the air is reduced, and the user experience feeling is improved.
Owner:BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Improved methods to diagnose head and neck cancer and uses thereof

This disclosure provides a method for evaluating the prognosis of a head and neck cancer patient. The head and neck cancer may be human papillomavirus positive (HPV+) and originate in the upper aerodigestive tract (e.g. oropharynx, nasopharynx, nasal cavity, sinus, or hypopharynx). In addition, the disclosure provides a method for predicting a response of a head and neck cancer patient to a selected treatment. The disclosure also provides a method for generating an improved head and neck cancer biomarker signature for patient prognosis and uses thereof.
Owner:THE UNIV OF NORTH CAROLINA AT CHAPEL HILL

A nasal oxygen supply device

The present application belongs to the technical field of medical devices, and particularly relates to a nasal oxygen supply device, which comprises a nasopharyngeal tube and an oxygen supply tube; one end of the oxygen supply tube away from the nasopharyngeal tube is connected with an oxygen supply device; an adjusting valve is arranged between the nasopharyngeal tube and the oxygen supply tube; the adjusting valve comprises an oxygen supply chamber, a connecting chamber, a control chamber, a control cavity, a pressure relief chamber, an elastic diaphragm and an adjusting rod; one end of the oxygen supply chamber is in communication with the oxygen supply tube, and the other end is provided with an oxygen supply hole; the oxygen supply chamber is in communication through the oxygen supply hole; one end of the connecting chamber away from the oxygen supply chamber is connected with the control chamber and the nasopharyngeal tube at the same time; the control chamber is connected with the pressure relief chamber; one end of the pressure relief chamber away from the control chamber is provided with a pressure relief port; the elastic diaphragm is arranged between the control cavity and the adjusting chamber; the elastic diaphragm is connected with the adjusting rod; the outer wall of the adjusting valve is provided with an adjusting knob and an adjusting spring; the adjusting knob is in threaded connection with the adjusting valve; one end of the adjusting spring is in abutment with the adjusting knob, and the other end is in abutment with the adjusting rod.
Owner:PEKING UNIVERSITY FIRST HOSPITAL (PEKING UNIVERSITY FIRST CLINICAL MEDICAL COLLEGE)

Nasal delivery double-chain RNA / Mn < 2 + > nano-drug as well as preparation method and application thereof in immunotherapy

The invention discloses a nasal delivery double-chain RNA / Mn < 2 + > nano-drug as well as a preparation method and application thereof in immunotherapy. And adding the polymer into a solution containing double-stranded RNA and manganese salt, and self-assembling to form the nasal delivery double-stranded RNA / Mn < 2 + > nano-drug. The invention provides a new technical scheme for the barrier of the BBB. The nano delivery system has the advantages in the aspects of overcoming the BBB and improving the in-vivo biological distribution of the drug, and the surface of the nano carrier is modified with a ligand targeted to an endothelial cell overexpression receptor, such as ApoE peptide and the like, so that the drug can be delivered to penetrate through the BBB; a non-invasive nasal-brain delivery strategy becomes a new scheme for improving drug availability and reducing toxic and side effects, the drug can bypass BBB and rapidly enter brain parenchyma through olfactory bulb and trigeminal nerve conduction pathways, and an immune drug delivered by the nasal cavity can rapidly enter nasopharynx-related lymphatic tissue (NALT) and is transferred to CLN through a lymphatic network around the nasal cavity, so that the immune drug can be rapidly delivered to the nasopharynx-related lymphatic tissue (NALT). Further, a potent local immune response aiming at the in-situ GBM is induced.
Owner:SUZHOU UNIV

Multi-degree-of-freedom flexible nasopharyngeal swab sampler

The present invention provides a multi-degree-of-freedom flexible nasopharyngeal swab sampler, which relates to the field of medical device technology. The nasopharyngeal swab sampler includes: a flexible swab, a pulley reduction assembly, a multi-directional bending control joint and a plurality of control ropes; each bending degree of freedom of the multi-directional bending control joint is correspondingly provided with two control ropes; the pulley reduction assembly includes: a pillar, a pulley group; the pulley group includes: a fixed pulley, a movable pulley and a sliding bracket; the nasopharyngeal swab sampler controls the bending direction and angle of the flexible swab by bending the multi-directional bending control joint, and the operation is simple and convenient; the elastic sliding of the sliding bracket and the pillar plays a deceleration and buffering role. No matter how fast the multi-directional bending control joint bends, the flexible swab always bends smoothly and gently, effectively preventing nasal damage caused by misoperation; and the elastic sliding connection between the sliding bracket and the pillar keeps the control rope in a taut state at all times, ensuring the control stability of the nasopharyngeal swab sampler.
Owner:HEFEI UNIV OF TECH

Extracranial method for promoting drainage of cerebrospinal fluid

Described herein is a method of preventing or treating a neurodegenerative disease comprising administering to a human an agent wherein the agent causes increased cerebrospinal fluid outflow through nasopharyngeal lymphatic plexus (NPLP), or the agent causes contraction and relaxation of annular smooth muscles covering deep cervical lymphatic vessels (dcLV).
Owner:INST FOR BASIC SCI +1

Improved nasopharynx breather pipe

The utility model belongs to the technical field of medical instruments, and particularly relates to an improved nasopharynx breather pipe. The improved nasopharynx breather pipe comprises a main pipe body, a movable sleeve and a fixing band. The main pipe body comprises a connector arranged at one end; the movable sleeve is detachably arranged on one side, close to the interface, of the main tube body, and comprises an elastic sleeve which movably sleeves the periphery of the main tube body, an air bag which is arranged at the end part of the elastic sleeve and is opposite to the nose of the patient, and a fixing assembly for fixing the elastic sleeve on the main tube body; and the fixing belt can be sleeved on the movable sleeve. After the main pipe body enters the pharynx of a patient through the nostril, medical staff adjust and fix the position of the elastic sleeve on the main pipe body through the fixing assembly according to the position of the nose of the patient, so that the air bag is fixedly located on the outer side of the nostril and abuts against the nose of the patient, and due to the fact that the air bag is made of flexible materials, pressure applied to the nose of the patient is not large. The situation that the nose of a patient becomes red under long-time pressing of the nasopharynx breather pipe can be avoided, and the comfort level of the patient is improved.
Owner:THE 907TH HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY JOINT LOGISTICS SUPPORT FORCE

Convenient-to-operate soft palate protective sleeve with sleeve guide

ActiveCN121101653ASurgeryNasal Cavity EpitheliumPalate muscle
The invention provides a convenient-to-operate soft palate protective sleeve with sleeve guide, and relates to the technical field of soft palate protective sleeves, the convenient-to-operate soft palate protective sleeve comprises a nasal cavity sling, an oral cavity sling is arranged on the side surface of the nasal cavity sling, and an unfolding mechanism is arranged between the nasal cavity sling and the oral cavity sling; the expansion mechanism is used for expanding the protection sleeve in the oral cavity to protect the soft palate, a sleeve is slidably installed on the surface of the nasal cavity sling and the surface of the supporting mechanism, and a pipeline is arranged in the center of the sleeve. The protective sleeve is guided to sequentially pass through the nasopharynx and the oropharynx and is smoothly led out of the oral cavity by means of the tubular structure, medical staff do not need to repeatedly test and adjust the position, and operation time is greatly shortened.
Owner:GUANGDONG YINRUI MEDICAL TECHNOLOGY CO LTD