The present invention constructs a “
radar”
system for dynamically monitoring and guiding ongoing clinical trials. In one embodiment, the
system partitions the
data space into 3 primary regions comprising “favorable”, “hopeful” and “undesirable” to reflect the trial status. In one embodiment, the undesirable region comprises a futility region, and the favorable region comprises a successful region. In one embodiment, the boundaries defining these regions are subject to adjustment as the
clinical trial proceeds. In one embodiment, the accumulative
treatment effect, data trends, stopping boundaries, trajectory and other information are graphically displayed on the “
radar” screen. In one embodiment, the
system takes learning from the observed and accumulated data and performs simulations to intelligently guide the trials. In one embodiment, the system is used in re-analysis or diagnosis of clinical trials already completed and provides guidance for
clinical trial design or amendment.