The invention relates to a novel three-dimension shoulder joint artificial prosthese, formed by a spherical cap element 1, a handle 3, an incline element (bar wedge 4 and arc block 6), and a torsion element (round plate 2 and cylinder block). The invention realizes the three-dimension design of shoulder joint, via tooth meshed, and uses incline element to realize the incline angle adjustment between 115 degrees and 140 degrees, and uses the torsion element to realize the torsion angle adjustment between -20 degree and +20 degrees, uses the eccentric design of spherical cap element 1 to meet the demand of eccentric distance of head of humerus, while the eccentric distances are 2.5mm, 3.5mm, and 4.0mm, uses the detachable arrangement of incline element and torsion element to confirm the repeatable adjustment of parameters. And the rod 9 of handle has plum blossom section to avoid the handle being rotated in the marrow. The invention is characterized in the large adjustment range of prosthese parameters with repeatable adjusting ability. The invention has simple structure, high reliability and simple operation.