57results about How to "Solve clinical problems" patented technology

The invention discloses an anti-restenosis digestive tract stent which is characterized in that a main body (1) is formed by connecting a plurality of stent units (2) and an easily-bent connecting part (3), wherein two ends of the connecting part (3) are respectively connected with the corresponding stent unit (2), the main body (1) is of a right circular cylinder structure which is easy to bend or a composite structure which is easy to bend and consists of a cylinder and a cone; and each stent unit (2) is of an integral structure formed by carving a metal pipe material or a structure formed by weaving a silk material, and the connecting part (3) is formed by weaving a metal line material or plastic line material with good flexibility. The anti-restenosis digestive tract stent has better radial supporting strength and better compliance, and ensures that the stent has the advantages of more accuracy of positioning, difficulty in translocation, low restenosis incidence and the like.

The invention provides a primer set, a kit and a detection reaction system for detecting PKD1 gene mutation through the long fragment PCR and high-throughput sequencing technology, a non-diagnosis-purpose method for external PKD1 gene mutation detection, a non-diagnosis-purpose method for external PKD1 gene analysis and a method for detecting new mutation sites on the PKD1 gene. According to the method, the primer set is used for carrying out long fragment PCR amplification on the PKD1 gene of a sample, and detecting or analyzing is carried out through high-throughput sequencing. The autosomal dominant genetic polycystic nephrosis (adult polycystic nephrosis) can be diagnosed through the assistance of a detection result, previous unknown new mutation on a plurality of PKD1 real genes can be obtained and supplied to doctors or researchers so that the relevance between the mutation and the adult polycystic nephrosis can be studied.

The invention provides an invisible appliance which comprises a single-jaw appliance and/or a double-jaw appliance. The single-jaw appliance comprises a maxillary tooth socket and a functional auxiliary part, and the double-jaw appliance comprises a double-jaw tooth socket and a functional auxiliary part. The double-jaw tooth socket comprises an upper jaw tooth socket, a lower jaw tooth socket anda connecting occlusal plate, the functional auxiliary part is selected from at least one of a palatal side plate, a lingual guide wing, an anterior tooth occlusion opening assembly and an extraoral traction assembly, and the anterior tooth occlusion opening assembly comprises a gingival margin bulge and a stress application pad; the extraoral traction assembly comprises an outer side tube and anextra-oral traction bow, and all parts are made of transparent or semi-transparent materials, so that the appliance is invisible. The appliance has a wide clinical application range, is suitable for malocclusion deformity of bone surface type II malocclusion and mild type III and can provide an efficient correction force system in the three-dimensional direction and especially greatly improve thecorrection efficiency in the vertical direction.

The invention provides a medical technology inspection automatic recommendation reservation method and system, a device and a storage medium. The medical technology inspection automatic recommendationreservation method comprises: receiving a medical technology inspection application form uploaded by a hospital information system; matching a reservation queue corresponding to each medical technology inspection item in the medical technology inspection application form according to a preset queue matching template; screening and sorting each of the reservation queues according to a preset medical technology inspection conflict rule to obtain an optimal queue combination; obtaining a reservation period of each reservation queue in the optimal queue combination, and generating a recommendation reservation period table of the medical technology inspection application form according to the optimal queue combination. The method can meet the integrated reservation of medical technology inspection items such as ultrasound, radiation, endoscope and dynamic electrocardiogram, can automatically recommend the optimal time for patient inspection, can solve the clinical practical problem, can optimize the medical technology inspection reservation process, can complete reconstruction of the patient consultation process, can improve the working efficiency of medical technology inspections, andcan improve the service quality.

The invention discloses non-shielding fracture reduction forceps. The non-shielding fracture reduction forceps comprise a right forceps piece (1) and a left forceps piece (2) hinged to the right forceps piece (2) through a pin (3). A left clamping arm is formed at the front end of the right forceps piece (1), and a right handle is formed at the rear end of the right forceps piece (1). A right clamping arm is formed at the front end of the left forceps piece (2), and a left handle is formed at the rear end of the left forceps piece (2). The non-shielding fracture reduction forceps are characterized in that the left clamping arm is divided into a left bent arm (5) and a left clamping section (10), the left bent arm (5) is bent continuously in the horizontal direction to form an arc shape and is bent continuously by an alpha angle in the perpendicular direction; the right clamping arm is divided into a right bent arm (4) and a right clamping section (11), the right bent arm (4) is bent continuously in the horizontal direction to form an arc shape and is bent continuously by an alpha angle in the perpendicular direction; an operation cavity (12) is formed between the left clamping arm and the right clamping arm; the inner side of the left clamping section (10) and the inner side of the right clamping section (11) are each one third of a circular arc face, a clamping cavity (13) is formed between the left clamping section (10) and the right clamping section (11), and the longitudinal section of the clamping cavity (13) is two thirds of the circular arc shape.

The invention relates to universal adapters of multiple sequencing platforms, a library construction method suitable for the multiple sequencing platforms and a kit. Based on design of the universal adapters of the multiple sequencing platforms and development of a matched fast library construction process, DNA fragmentation, end repair and dA tailing adding are completed through a one-step reaction, and then two ends of a DNA fragment are connected with the universal adapters of the multiple sequencing platforms so that a constructed library can conduct high-throughput sequencing on the multiple sequencing platforms at the same time. By means of the method, the clinical problem that due to difference of sequencing platforms, different sequencing platform libraries need to be constructed for multiple times is solved, library duration is greatly shortened, the library construction cost is greatly reduced, and meanwhile, due to a low demand for the starting template amount of single library construction, consumption of clinical samples is greatly reduced.

The invention provides a stable PGE1 lyophilized emulsion and a preparation method thereof. In particular, by adding vitamin E and refined cane sugar or glucose or a mixture composed of refined sugar and glucose according to a certain ratio, the PGE1 lyophilized emulsion is substantially improved in physical and chemical stability, and thus is capable of bearing severe variation of conditions during freeze drying. The prepared lyophilized product is plump in appearance, is white loose blocks or powder, is good in redissolving property, controllable in quality, good in reappearance and low in rejection rate; also because the usage amount of auxiliary agents is reduced, the production cost of the product is reduced, and the side effects caused by too much added lyophilized preparation auxiliary agents are overcome; and the product is relatively safe to use by patients, and the product is prolonged in validity period and reduced in requirements on production, transportation and storage conditions.

The invention provides an iron-based magnetic nano-particles regionally modified intraocular lens and a preparation method and application thereof. The intraocular lens comprises an intraocular lens body and iron-based magnetic nano-particles for coating of a connection layer, which is connected to the equatorial region of the intraocular lens body. The intraocular lens is obtained through hydroxyl modification of the equatorial region of the intraocular lens body and chemical bonding of the iron-based magnetic nano-particles. The intraocular lens has no influence on optical performance of the intraocular lens body, has good biocompatibility, can controllably kill lens epithelial cells at real time, and can effectively reduce recurrence rate of cataract so as to solve the great clinic problem of after-cataract. The intraocular lens enables chemicals to selectively act on the lens epithelial cells rather than damage other intraocular tissues. The invention provides a new idea, a new approach and a new method for prevention of after-cataract.

The invention provides a Chinese medicinal preparation for treating gynecological inflammation, and relates to a Chinese medicinal preparation. The Chinese medicinal preparation solves the problems of high toxicity and high medicament resistance rate of conventional western medicaments, poor treatment effects of conventional Chinese medicaments, main concentration on prescription medication of clinical treatment, and no Chinese patent medicament capable of being widely applied to clinical genital tract infection of women and being clinically applied. The Chinese medicinal preparation is prepared from amur corktree bark, atraotydin, common cnidium fruit and dandelion. Pharmacodynamic and toxicological experiments prove that the Chinese medicinal preparation for treating the gynecological inflammation has the advantages of long-term use, safety, no toxic or side effects, antibiosis, anti-mycoplasma, good antiphlogosis effect, and good treatment effect. The Chinese medicinal preparation can be prepared into the Chinese patent medicament for the clinical genital tract infection of women, and solves the problems of main adoption of the prescription medication of clinical treatment, and no Chinese patent medicament capable of being widely applied to clinical genital tract infection of women and being clinically applied.

The invention relates to a method for predicting liver cancer risk through high-throughput analysis of hepatitis B virus genome RT/S region sequence characteristics by a machine learning model, and belongs to the technical field of genome sequence calculation. The method comprises the steps of: selecting a corresponding feature calculation method to complete construction of an RT/S region sequencefeature matrix of the HBV genome; and training the data set by adopting a machine learning model, and finally predicting the risk probability of suffering from liver cancer. The method based on artificial intelligence is characterized in that a series of feature algorithms are applied to learning of machine learning model training in the field of HBV genome RT/S region sequence data processing; high-dimensional genome data sequencing signals are converted into clinical risk degree judgment of suffering from diseases, and computer-assisted high-risk early warning and early diagnosis of suffering from liver cancer of HBV infected people are facilitated.

The invention discloses a traditional Chinese medicine composition for preventing or treating ulcerative colitis canceration. The traditional Chinese medicine composition is prepared from the following crude drugs in parts by weight: 10-210 parts of gecko, 10-210 parts of earthworm, 10-210 parts of pill bug and 5-150 parts of honeybee pupae. The honeybee pupae can be replaced with honeycomb. The invention also discloses a pharmaceutic preparation for preventing or treating ulcerative colitis canceration and a preparation method thereof, and the dosage forms of the pharmaceutic preparation include pills, capsules, tablets, powder, granules, oral liquid, clysis fluid and decoction agent. By adopting the traditional Chinese medicine composition, the clinical problem of ulcerative colitis canceration is solved, the occurrence rate of ulcerative colitis canceration is reduced, the side effect of the drug is small, and the financial burden of the patient is small. The traditional Chinese medicine composition can interfere the occurrence of ulcerative colitis canceration, and plays an important role in colon tissue imflammation-cancer conversion, and the treatment effect is superior to that of a mesalazine group, and is obviously superior to that of a rehabilitation new liquid group.

The invention belongs to the technical field of veterinary medicine, and discloses anti-fever toxin-eliminating oral liquid and a preparation method thereof. Per 1000ml of oral liquid is prepared from the following medicinal materials in proportion by weight: 300 to 350g of radix scutellariae, 250 to 300g of fructus gardeniae, 200 to 250g of isatis roots, 200 to 250g of fructus forsythiae, 200 to 250g of rhizoma dryopteris crassirhizomae, 200 to 250g of wild chrysanthemum flowers, 200 to 250g of radix bupleuri and 200 to 250g of herba houttuyniae. The oral liquid provided by the invention has the advantages that through study and application for near three years, the curative effect in aspects of preventing and controlling poultry cold and fever is exact; the disease condition can be effectively prevented and controlled; the economic loss is reduced; the cost is low; the oral liquid is suitable for being popularized in poultry culture; the defects of vaccine and other medicine are overcome; the clinic trouble of culture farmers can be avoided.

The invention discloses a nano water absorbing material sandwich type human body temperature adjusting nursing article and a use method thereof. A layer of adsorbing cloth with nano water absorbing materials evenly distributed is sandwiched between two layers of non-water-absorbing water-permeable cloth or non-woven fabric, interlayer cloth with two or more division cells is formed through division by linear or curviform division lines, the interlayer cloth is cut and sewn into caps, vests, physical therapy bags, pillows, felt, cushions, scarves, gloves, socks and other articles according to application requirements, after the relevant articles expand after absorbing water, the articles are covered with jackets after heating or freezing, and the articles can be used for adjusting the surface temperature of the human body. The nano water absorbing material sandwich type human body temperature adjusting nursing article is small in size, easy to fold and convenient to carry during drying, has the advantages of being safe, reliable, high in cost performance, multifunctional, easy and convenient to operate and the like, and can solve the problems that traditional temperature adjusting articles have raw material manufacturing limitation and function simplification and are high in transport, storage and treatment cost, and great significance is achieved for achieving energy saving and environment friendliness and improving the life quality of populations after application and popularization.

The invention provides a degradable metal skull repairing reticular implant. The degradable metal skull repairing reticular implant comprises: bridge line structures used for realizing in-plane stretching or compression deformation under the action of stress; and an island-shaped structure used for achieving out-of-plane deformation in a direction perpendicular to the reticular implant so as to form a net bag structure, wherein the plurality of bridge line structures are connected with each other, then are wound on the peripheral side of the island-shaped structure and are connected with the island-shaped structure to form reticular brackets, and a plurality of the reticular brackets are connected with each other to form the reticular implant. The reticular implant can adapt to intracranial pressure change after implantation, generates self-adaptive deformation in the development process of a child, continuously provides stable mechanical support, and avoids untight attachment and displacement with a skull, so the problems of poor adaptability and the like of a conventional skull repairing device are solved, and the situation that mechanical supporting effect on an implantation area is lost due to structural damage or large-area falling occurs in a degradation process before the degradable brackets are completely degraded is completely avoided.

The invention discloses a blood vessel puncture mouth I-shaped blanker for interventional medicine and a manufacturing method thereof. The blanker is of an I-shaped structure shown in figure (1), andis composed of a blanker body (1), a blanker inner sheath (2), a blanker outer sheath (4), a control disc (3), a control disc (5), an inner core pipe (6), an inner core pipe (7) and a connecting line(8). The I-shaped blanker is made from biodegradable macromolecular polymers, the inner wall and the outer wall of a blood vessel are clamped through an inner buckling disc and an outer buckling discwith high-elasticity memory performance, the blanker can be completely degraded within 4-6 weeks, and regeneration and restoration of the walls of the blood vessel are benefited. The blood vessel puncture mouth I-shaped blanker is easy and convenient to operate, a blood vessel puncture mouth can be effectively closed, postoperative risks can be effectively reduced, and the pain and the strength ofmedical care are relieved.

The invention relates to an oral lip moisturizing apparatus capable of continuously feeding minor amount of water. The oral lip moisturizing apparatus comprises an ear hanging bracket, a face side bracket, a horizontal bracket, a water bag, a water drainage pipe, and a lip water seepage structure. The oral lip moisturizing apparatus is characterized in that the ear hanging bracket is hung to the ear; the front part of the ear hanging bracket is connected to the face side bracket on the face side; a bend is arranged in front of the face side bracket; the rear part of the bend is connected withthe horizontal bracket parallel to the direction of the mouth; the lip water seepage structure is arranged between the left horizontal bracket and the right horizontal bracket; a water drainage pipe fixing structure is arranged on the face side bracket and the horizontal bracket; the drainage pipe is fixedly arranged on the side of the face side bracket and the horizontal bracket through the drainage pipe fixing structure, and is introduced to the lip water seepage structure through the face side bracket and the horizontal bracket; the drainage pipe is connected with an above water bag; a water outlet is formed in the lip water seepage structure; a micrometeor control structure is arranged in the hollow cavity. According to the oral lip moisturizing apparatus disclosed by the invention, the above structure is adopted, so that continuous feeding minor amount of water can be realized, and the problems of xerocheilia of a patient and oral inflammation of patient suffering serious illnessand the like are effectively solved.