The invention provides a switched capacitor adjustable gain amplifier with high gain and low noise. The switched capacitor adjustable gain amplifier comprises an external signal source, a square wavegenerator, a switched capacitor integrator and a feedback circuit with a signal amplification function, wherein the external signal source and the square wave generator are connected to the switched capacitor integrator, the switched capacitor integrator outputs through the feedback circuit, the switched capacitor integrator comprises seven COMS switching tubes opened by forward pulses, a samplingcapacitor, an adjustable feedback capacitor and an integrating capacitor, and the feedback circuit comprises an operational amplifier. According to the switched capacitor adjustable gain amplifier, the time-reduced integrated frequency of the feedback capacitor is equivalent to the reduction of the capacitance value of the feedback capacitor; the noise of the PGA is reduced while the high gain isrealized; meanwhile, the layout area of the circuit is not increased, the power consumption and the cost are reduced, the detection precision and the detection efficiency of the circuit are improved,and the switched capacitor adjustable gain amplifier is suitable for various sensor interfaces, signal conditioning chips and signal links and has a great market development prospect in automotive electronics, white household appliances, industrial automation and the Internet-of-things.