The invention relates to a making device and method for large-section and large-thickness
brain tissue slices, and belongs to the related technical field of biological
histology and
pathology experiments. The device mainly comprises a base with a groove, and the groove is used for preventing interference between a knife and the base when the knife is used for
cutting brain tissue; the top of the base is detachably connected with a locating plate and a stop block separately, and the height of the stop block is higher than that of the locating plate; the stop block is a cuboid, and the left side face serves as the datum plane of
brain tissue to be
cut, wherein the locating plate is provided with guide grooves used for guiding the knife. According to the making device, the locating plate and the stop block are detachably connected, and therefore replacing is convenient; the guide grooves comprise one chopping guide groove and four
slicing guide grooves, the distances between the
slicing guide grooves and the side wall of the locating plate are different, and therefore the brain tissue slices with different thicknesses can be
cut. According to the making device and method for the large-section and large-thickness brain tissue slices, the problem that large-section and large-thickness brain tissue slices of pig brains, cattle brains and the like are difficult to manufacture at high quality is effectively solved.