The invention relates to a system and a method which provide real-time and reliable multiple people voice interaction in network games. The system comprises a telecommunication network, a telephone exchange, the Internet, a game server platform in the Internet and a game client platform in the Internet, wherein, the game server platform is internally provided with a game server control module, a player information data base, a voice server control module and a terminal information data base; the game client platform is internally provided with a game client control module and a voice client control module. The method of the invention combines the IP telephony and the telecommunication network provided with a QoS guarantee, fulfills seamless integration with the game server control module and the game client control module through the voice server control module and the voice client control module, constructs two control platforms, and provides real-time, reliable, convenient and stable multiple people voice interaction. The operation method is simple, easy to master and relatively independent. Therefore, the system and the device ensure that game manufacturers can concentrate on the development of the network games and have rather good popularization and application prospect.