The invention provides a fast butt-joint locking mechanism which comprises a driven end assembly and a driving end assembly. The driven end assembly comprises a sleeve, a night bolt, a baffle plate, arelief spring and an elastic cylindrical pin; after the night bolt is clamped to one end of the sleeve and the relief spring is placed into the other end of the sleeve, limiting is carried out through the baffle plate; the baffle plate is fixed onto the sleeve through the elastic cylindrical pin; and the driving end assembly comprises a bolt, a plunger latch, an ejector rod, a bolt base, an installation bottom plate, a needle roller bearing, an earless clamp spring and a working spring. The fast butt-joint locking mechanism is simple to operate when in use; no any other operation tool is needed during locking, and only the end surfaces of the driving end assembly and the driven end assembly need to close up, so that fast butt-joint locking can be realized; and during unlocking, an unlocking key is firstly used for enabling the ejector rod to jack the night bolt so as to realize arming, and meanwhile, the driving end assembly and the driven end assembly are forced to withdraw reverselyso as to realize fast unlocking. The locking mechanism has the characteristics of convenience, fastness, capability of being used repetitively for multiple times, and high reliability.