The invention belongs to the field of
cosmetics, and discloses a stable oil-soluble
polypeptide composition, which comprises the following components: polypeptide, a solubilizing agent, and an oily
solvent; the solubilizing agent has an
octanol water
partition coefficient of 1.70 to 1.90 or an HLB value of 8.0 to 10.0; the polypeptide is selected from at least one of palmitoyl
tripeptide-7, palmitoyl
tripeptide-1, palmitoyl
tripeptide-5, palmitoyl tripeptide-8,
palmitoyl tetrapeptide-5,
palmitoyl tetrapeptide-7,
palmitoyl tetrapeptide-10, and palmitoyl pentapeptide-4; and the solubilizing agent is at least one selected from the group consisting of
ethylhexylglycerin,
glycerol caprylate, polyoxyethylene
fatty acid,
sorbitan laurate, and polyoxyethylene oxypropylene oleate. The oil-soluble
polypeptide composition of the present invention is easy to be added to a cosmetic of a full oil formula, and has good compatibility, the stability of the oil-soluble
polypeptide composition is good, the product is not easy to grow
bacteria, compared with traditional water-soluble
peptide products, the product does not need to add preservatives, and the formula is
safer.