51 results about "Orthopedic disorders" patented technology

The present invention generally provides a cannula system that is readily maneuverable in an operating room setting, can be used to expose different instrumentalities to a target site, and has directional capabilities to allow the user to treat multiple quadrants or areas of a target site. The present invention provides cannula systems including these different instrumentalities as well as methods of operating these cannula systems and methods of treating orthopedic conditions using these cannula systems.

The invention discloses a Chinese medicine composition for treating orthopedic disorders and a preparation method thereof. The Chinese medicine composition comprises the following components: 140-160g of rhizoma drynariae, 90-110g of eucommia bark, 90-110g of teasel root, 90-110g of bidentate achyranthes root, 20-30g of frankincense, 20-30g of myrrha, 140-160g of the red-rooted salvia root, 40-60g of flos carthami, 90-110g of panax pseudoginseng, 90-110g of szechuan lovage rhizome, 10-20g of prepared common monkshood mother root, 10-20g of prepared radix aconiti kusnezoffii, 90-110g of Chinese clematis, 90-110g of fructus chaenomelis lagenariae, 140-160g of radix astragali, 90-110g of Chinese angelica, 140-160g of prepared rehmannia root, 90-110g of ground beeltle, 40-60g of scorpio, 40-60g of lumbricus, 90-110g of snake slough, 140-160g of radix curcumae, 15-30g rhizoma curcumae longae and 40-60g of liquoric root. The invention has the advantages of special formula, remarkable effect, simple preparation method and easiness in operation.

Methods, compounds, compositions, kits and articles of manufacture comprising anti-connexin agents for treatment of orthopedic disorders, diseases, or conditions, and improving recoveries and outcomes of orthopedic procedures or surgeries.

The invention discloses a bulk drug for treating orthopaedic diseases. The bulk drug is Chinese teasel root saponin VI and is prepared by extracting traditional Chinese medicinal materials which contain the Chinese teasel root saponin VI; the weight percentage content of the Chinese teasel root saponin VI occupies 95.0 to 99.9 percent of the total amount of an extract of the Chinese teasel root saponin VI; and the chemical name of the bulk drug is 3-O-alpha-L-arabopyranose ivy sapogenin-28-O-beta-D-glucopyranose(1-6)-beta-D-glucopyranoside. The invention also discloses a method for preparing the bulk drug - the Chinese teasel root saponin VI. The method comprises the following steps of extraction, concentration, separation of the total saponin, decolorization and purification and refinement. The preparation method has the advantages that the preparation method has high extraction rate and low cost, is safe and environment-friendly and is suitable for industrialized mass production. The invention also provides application of the bulk drug in preparing medicines for preventing and treating the orthopaedic diseases including osteoporosis, fracture and osteoarthritis.

Methods, compounds, compositions, kits and articles of manufacture comprising anti-connexin agents for treatment of orthopedic disorder, disease, or condition, and promoting post-surgical wound-healing.

The invention discloses an exosome preparation derived from a stem cell. The exosome preparation is an exosome secreted by a Fe3O4 superparamagnetic nanoparticle stimulating the stem cell. The invention further provides the application of the exosome preparation in preparing a pharmaceutic preparation for promoting mesenchymal stem cell osteogenic differentiation and the application of the exosomepreparation in preparing a biological agent for treating orthopedic disorders or bone repair materials. In consideration of the complicated pathophysiologic process of osteonecrosis and bone defects,the exosome preparation prepared by the exosome secreted by the Fe3O4 superparamagnetic nanoparticle stimulating the stem cell is adopted, intramuscular administration can be adopted at local bone defect parts, or local filling is performed after the exosome preparation is mixed with absorbable gel, the exosome preparation directly reaches the focus, the osteogenic activity of the mesenchymal stem cell is motivated, the deposition of osteoblasts is promoted, and the repair of the osteonecrosis or bone defects is promoted.

The present invention discloses an orthopedic disease treatment external application traditional Chinese medicine composition, a preparation method and an application thereof. The orthopedic disease treatment external application traditional Chinese medicine composition is a drug preparation prepared from the following traditional Chinese medicine raw materials by weight: 20-60 parts of cape jasmine, 10-40 parts of curcuma longa l, 5-30 parts of angelica dahurica, 5-30 parts of clematis chinensis, 5-30 parts of papaya, 1-5 parts of boswellia carteri, 1-5 parts of commiphora myrrha eng1, 0.2-2 parts of camphor, and 0.2-2 parts of borneol. The invention discloses the application of the orthopedic disease treatment external application traditional Chinese medicine composition in preparation of drug for treating acute and chronic soft tissue injuries, joint sprains, hyperosteogeny, rheumatalgia, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, lumbar muscle strain and sciatica. The orthopedic disease treatment external application traditional Chinese medicine composition is the toxic herb-free pure traditional Chinese medicine preparation, and has characteristics of significant treatment effect, no shift, low cost, high efficacy, rapid effect, and no toxic-side effect.

The invention discloses an externally-applied traditional Chinese medical composition for treatment of orthopedic diseases and a preparation method and an application method thereof. Angelica sinensis, ligusticum wallichii and other traditional Chinese herbs are mixed, crushed and packed into a cloth bag, vinegar is poured into the cloth bag, and then the cloth bag is heated and applied on an infected part. The traditional Chinese medical composition can be used for the treatment of the orthopedic diseases, the blood circulation can be promoted effectively, tissues of local injuries can be recovered, internal factors can be eliminated completely, and the purpose of complete treatment can be achieved.

The invention discloses a traditional Chinese medicine oral preparation for treating orthopedic disorders and a preparation method thereof. The traditional Chinese medicine oral preparation disclosed by the invention is an ancestral secret recipe for treating the orthopedic disorders, has unique curative effects on the orthopedic disorders such as fracture, hyperosteogeny, femoral head necrosis, protrusion of intervertebral disc, and arthritis, and is a traditional Chinese medicine secret recipe handed down from ancestors. The formula and the preparation method are as follows: 20 kinds of traditional Chinese medicines, namely nux vomica, ephedra, Chinese angelica, cassia twig, radix angelicae pubescentis, radix glycyrrhizae, radix paeoniae alba, mastix, myrrh, eucommia, achyranthes bidentate, Chinese quince, notopterygium root, drynaria baronii, gastrodiae tuber, melon collaterals, stiff silkworm, piper wallichii, lindera aggregata, and musk, are mixed, grinded, and screened, the obtained fine powder is placed into capsules to form a capsule preparation, or is added with honey to form a sublimed preparation. The traditional Chinese medicine oral preparation for treating the orthopedic disorders has the characteristics that the pure traditional Chinese medicine preparation has no toxic or side effects on a human body; the most common traditional Chinese medicine is adopted; the raw materials are easy to obtain; the cost is low; the recipe is used by many generations of people, the effective percentage can reach 100%.

A method for minimally invasive surgery using therapeutic ultrasound in spine and orthopedic orthopedic procedures. The method includes a minimally invasive access port, a therapeutic ultrasound probe to treat a targeted area through the port, and a protective sheath that enables application of the therapeutic ultrasound without causing unintended tissue damage.

The subject invention is related to a cell-mediated gene therapy treatment for orthopedic disease using a member belonging to the transforming growth factor-β (TGF-β) superfamily. TGF-β gene therapy as a new treatment method for degenerative arthritis is demonstrated. After transfection of TGF-β cDNA expression vectors into fibroblasts (NIH 3T3-TGF-β1), the cells were injected into rabbit achilles tendon and knee joints with artificially-made cartilage defects. Intratendinous injections were performed to determine the optimal concentration for in vivo expression. Partially defected cartilage model was made to simulate degenerative arthritis of the knee joint. The partial cartilage defect treated with the cell-mediated gene therapy procedure was covered by newly formed hyaline cartilage which indicates that the cells survived and stimulated matrix formation in this area. Completely denuded cartilage areas were covered by fibrous collagen.

The invention relates to a composition for treating orthopedic diseases. The composition is mainly prepared by processing the following active ingredients in certain parts by weight: radix angelicae pubescentis, olibanum, myrrha, sanguis draconis, semen raphani and bletilla. The composition has a good curative effect on cervical spondylosis, scapulohumeral periarthritis, lumbar intervertebral disc hernia, femoral head necrosis, fracture, contusion and sprain, osteoproliferation and other orthopedic diseases, can achieve the effective rate of more than 93%, and is small in side effects and fewer in varieties of the active ingredients, thereby saving the cost.

The invention discloses a medicine for treating orthopaedic diseases and the preparation method and application thereof. The medicine is made from 10 to 40g of vermiculite, 10 to 40g of muscovite, 10to 40g of saffron, 20 to 50g of notoginseng, 20 to 50g of dragons blood, 20 to 50g of dipsacus root, 20 to 50g of eucommia bark, 20 to 50g of cassia twig, 20 to 50g of achyranthes root, 20 to 50g of rhizoma drynariae, 20 to 50g of pyrite, 20 to 50g of wolfberry barks, 20 to 50g of acanthopanax bark, 30 to 60g of ledebouriella root, 30 to 60g of frankincense, 20 to 50g of myrrh, 20 to 50g of ground beetle, 200 to 1000g of subcapital bone of black boar, and 100 to 1000g of the lower three bones of red cock. The medicine of the invention has the functions of stimulating circulation to end stasis, reducing swelling and relieving pain, and activating the regeneration of osteocytes and myeloid cells, and is used clinically for treating fracture, bone crack, comminuted fracture, injury of sinews or bones, and muscle sprain.

A wearable device that enables adjustable resistance to the extremity of a user using an attachment system and associated eddy current braking system. The wearable resistive device can be used for physical therapy made necessary due to weakness caused by neuromuscular diseases, such as stroke and cerebral palsy, orthopedic disorders, general disuse, or even for overall fitness.

A wearable device that enables adjustable resistance to the extremity of a user using an attachment system and associated eddy current braking system. The wearable resistive device can be used for physical therapy made necessary due to weakness caused by neuromuscular diseases, such as stroke and cerebral palsy, orthopedic disorders, general disuse, or even for overall fitness.

The invention belongs to the field of the traditional Chinese medicine composition, and provides a traditional Chinese medicine composition used for hyperostosis, a preparation method and the application of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the efficacies of dispelling wind and removing obstruction in the meridians, invigorating the circulation of blood, carrying out analgesic therapy, removing blood stasis and hemostasis, promoting qi circulation to relieve pain, relaxing tendons, activating collaterals, stimulating the menstrual flow and removing stasis and has a good curative effect on orthopedic disorders including various types of neck and shoulder hyperostosis osteoarthrosis, and cervical spondylosis which are caused by rheumatoid obstinate arlhralgia, numbness contracture, blood stasis menstrual block and abdominal mass and palpatable abdominal mass. Meanwhile, the invention also provides a preparation method for preparing the composition into various dosage forms, and therefore, the advantages of various medicine use dosage forms and wide applicable range are realized. The traditional Chinese medicine composition disclosed by the invention can be widely applied to various types of neck and shoulder hyperostosis osteoarthrosis and cervical spondylosis.

The invention belongs to the field of traditional Chinese medicine and particularly relates to a medicine composition for treating femoral head necrosis. The invention discloses a medicine for treating an orthopedic disease, and a preparation method, a test method and an application of the medicine. The medicine composition is prepared by taking and mixing the following raw materials in parts by weight: bitter nightshade, phtheirospermum japonicum and herb of manybranch meadowrue, adding 5-15 times of water into the medicinal materials for microwave extraction for 1-5 times, 15-60min each time, merging extracts, condensing, drying, grinding into fine powder, adding an auxiliary material, mixing and preparing into a granule. The medicine composition can be used for preparing a medicine for treating the femoral head necrosis. The invention further provides the test method of the medicine composition.

A composition for enhancing treatment of orthopedic ailments stimulates iNOS and enhances treatment of orthopedic ailments when a pharmaceutically effective amount is administered over a sufficient period of time. The composition comprises ginger, Muira puama, Paullinia cupana, and at least one of the group consisting of L-arginine and L-citrulline.

The invention provides an auxiliary system for improving orthopedic diagnosis decision efficiency and a method thereof, and the method comprises the steps: obtaining the illness state information of a first patient, the illness state information comprises examination image information, and obtaining a first disease feature information set, wherein the first disease feature information set comprises a first key point information set and a second key point information set; constructing a first structure three-dimensional model diagram according to the first disease information set; obtaining a first correction parameter according to the first structure three-dimensional model diagram; correcting the first key point information set and the second key point information set according to a first correction parameter to obtain a third key point information set and a fourth key point information set; and inputting the third key point information set and the fourth key point information set into an orthopedic diagnosis evaluation model to obtain a first evaluation result, sending the first evaluation result to an expert platform, and obtaining a second evaluation result according to expert opinions. The system and the method solve the technical problem that the prior art can only assist in the diagnosis of orthopedic diseases with obvious characteristic points. and therefore, the application range is small.

The invention provides an application of N-acetyl-D-glucosamine in preparing medicines for treating orthopedic disorders as well as the medicines and health-care products, and relates to the field ofmedicines. The invention provides the application of the N-acetyl-D-glucosamine in preparing the medicines for treating the orthopedic disorders; and with the application of N-acetyl-D-glucosamine which serves as an active ingredient, the orthopedic disorders can be relieved or treated, with a short treatment cycle and without toxic and side effects.

The invention relates to a kidney-invigorating and tendon-reinforcing capsule and a preparation method thereof. The content medicinal powder of the kidney-invigorating and tendon-reinforcing capsule is prepared from six types of traditional Chinese medicines and auxiliary materials such as cortex eucommiae, dragon's blood, malaytea scurfpea fruit, scorpio, fortune's drynaria rhizome and prepared rehmannia rhizome in a certain weight ratio. The kidney-invigorating and tendon-reinforcing capsule has the effects of invigorating the liver and the kidney, strengthening the bones and muscles, promoting blood circulation and removing obstruction in channels, and is suitable for treating orthopaedic diseases such as limb patellofemoral joint pain and pain in neck, waist and legs caused by deficiency of liver and kidney and stasis of tendons and channels. A prescription of the kidney-invigorating and tendon-reinforcing capsule is formed by screening formulas on the basis of continually summing up clinical experience, has a refined formula and strict blending, and follows the rules of comprehensively conditioning and treat both principal and secondary aspects of a disease in the traditional Chinese medicine. The kidney-invigorating and tendon-reinforcing capsule is free from toxic and side effects, and has a high treatment effective rate.

The invention discloses a needle body for treating orthopedic disorders. The needle body is a smooth rustless steel needle or a stainless steel needle and comprises a needle rod and a needle point; the length of the needle rod is 150 to 300m; the length of the needle point is 10 to 35mm; the needle rod has a circular cross section; and the diameter of the needle rod is 1 to 3mm. The invention has the advantages that: the needle body has a simple and reasonable structure, and can be used conveniently and safely, and by using the needle body, a patient can recover quickly after operation; and the needle body is particularly suitable for hospitals of all different levels, and clinics.

The invention relates to compositions and methods as part of a pharmacotherapeutic strategy that targets the endochondral ossification process in a pharmacologically selective and site-specific manner. A variety of orthopedic pathologies are caused by or associated with generalized or local dysregulation of endochondral ossification, for example trauma to the bone growth plate or diaphysis can cause a serious imbalance in bone growth, leading to progressive deformity that today can only be treated surgically. Dysregulated endochondral ossification is also behind heterotopic ossification, which arises in soft tissues and causes pain, decrease in mobility and other clinical problems. The invention therefore provides RARy agonist and antagonist nanoparticle compositions for treating abnormal endochondral ossification and bone growth that can deliver robust local therapeutic control over a particular long bone's growth with a long-lasting effect.

The invention discloses a topical traditional Chinese medicinal formula for treating orthopedic diseases such as lumbar pain, and relates to the field of traditional Chinese medicine. The topical traditional Chinese medicinal formula is prepared from ground beetles, myrrh, frankincense, safflower, caulis sargentodoxae, herba serissae, honeysuckle stems, caulis spatholobi, rhizoma homalomenae,, rhizoma cyperi, ligusticum wallichii and radix cynanchi paniculati, has the effects of promoting blood circulation, removing blood stasis, relieving swelling and pain, clearing and activating the channels and collaterals, nourishing yin, tonifying the kidney, strengthening muscles and promoting tissue regeneration, is greatly beneficial to treatment of the orthopedic diseases, and especially, has a good effect on lumbar disc herniation and bone joint pain. The formula can effectively treat the orthopedic diseases such as the lumbar pain, and has obvious effects on rheumatism and the bone joint pain. As a pure compound traditional Chinese medicinal preparation, the formula has no side effect on the human body. The processing method is simple, and easy to operate. Traditional Chinese medicinalfiltrates can be used for multiple times, so that the formula has low cost and high practical value.

The invention provides a plaster for treating orthopedic diseases. The plaster for treating the orthopedic diseases comprises the following effective components in parts by weight: 25-50 parts of floscarthami, 25-50 parts of radix angelicae sinensis, 25-50 parts of fructus gardeniae, 25-50 parts of semen persicae, 25-50 parts of paeonia albifora pall, 50-100 parts of frankincense, 50-100 parts ofmyrrh, 5-10 parts of dragon's blood, 25-50 parts of herba lycopodii and 1.25-2.5 parts of musk. The plaster for treating orthopedic diseases and the preparation method have the advantages of good effects, no allergy phenomenon, no blistering and a long pain-alleviating time, and many patients are cured.

The present invention provides novel PGF analogs. In particular, the present invention relates to compounds of general formula I, wherein R1, X and Z are as described below. The present invention also includes optical isomers, diastereomers and enantiomers of the general formula, as well as their pharmaceutically acceptable salts, biohydrolyzable amides, esters and imides. The compounds of the present invention can be used to treat a variety of diseases, such as orthopedic diseases. Thus, the present invention also provides pharmaceutical compositions containing these compounds. The invention also provides methods of treating orthopedic disorders using the compounds or compositions of the invention.

The invention discloses a whole body diagnosis and treatment device for orthopedic surgery diseases. The whole body diagnosis and treatment device comprises a bed board, wherein supporting legs are fixed at four corners of the lower surface of the bed board, a control switch is arranged on the front side surface of the bed board, supporting rods are respectively fixed at the left end and the right end of the edge of the rear side of the upper surface of the bed board, the upper end parts of the two supporting rods are fixedly connected by virtue of a square rod, and a sliding seat slidably connected with the square rod is arranged at the middle part of the square rod. The whole body diagnosis and treatment device for the orthopedic surgery diseases is complete in functions and easy to use, a signal is received by virtue of an X-ray receiver and is sent to a display for inspecting skeletons, the sliding seat can be adjusted, and when a patient with orthopedic diseases is treated, operation is easy, cleanliness and health are realized, working difficulty of medical personnel is reduced, the whole body orthopedic inspection can be carried out on the patient, regulation is convenient, a swinging rod is driven to move by virtue of a stepping motor to adjust a position of a supporting plate, and the part of the upper body does not need to move when the position of legs is regulated, so that the whole body diagnosis and treatment device for the orthopedic surgery diseases is easy to use.