51 results about "Syringe filter" patented technology

Devices and methods are provided for reducing matrix effects in protein precipitated bioanalytical samples comprising: a support, and a sorbent associated with the support capable of binding matrix interfering agents present in the bioanalytical sample, wherein the device further comprises filtering means for removing precipitated protein particles. The filtering means is a size exclusion filter or a polymeric or inorganic monolith having a maximum pore size less than or equal to the diameter of the particles to be removed from the sample, and can be integral with the sorbent or associated with the sorbent. The sorbent is characterized by sufficient selectivity between the matrix interfering agents and analytes of interest to provide retention of the matrix interfering agents while providing elution of the analytes of interest (e.g., a reversed phase or a polar modified reversed phase). Typical devices incorporating these features include luer syringe filters, individual filter cartridges, multiwell plates, pipette tips, or inline columns for multiple or single use.

The present invention provides a device comprising: a housing comprising a first opening for connecting to a liquid source, a second opening for connecting with an apparatus for drawing in and expelling liquid, and a valve means comprising a filter carrier and a filter, the filter carrier supporting the filter and being movable within the housing; wherein the valve means permits liquid that is drawn into the housing from the liquid source by the apparatus to enter the apparatus by bypassing the filter but which forces liquid that is subsequently pushed from the apparatus through the second opening into the housing to be filtered through the filter.

A syringe filter for containing a filter membrane is disclosed and includes first and second fluid distribution surfaces configured to be positioned on opposing sides of a membrane. An inlet port is in fluid communication with the first fluid distribution surface and a first plurality of distribution pathways formed on the first fluid distribution surface. An outlet port is in fluid communication with the second fluid distribution surface and a second plurality of distribution pathways formed on the second fluid distribution surface. The first plurality of distribution pathways is configured to distribute fluid flow from the inlet port to one side of the membrane while the second plurality of distribution pathways is configured to direct fluid flow from another side of the membrane to the outlet port.

The invention discloses a syringe filter which comprises an upper cover, a lower cover, a filtering membrane and coating rings, wherein the upper cover comprises an upper cover plate body and an input tube part; the lower cover comprises a lower cover plate body and an output tube part; the upper cover plate body is connected and matched up and down with the lower cover plate body; the edges of the filtering membrane are clamped and fixed through the upper cover plate body and the lower cover plate body, so that a cavity is divided into an upper part and a lower part; peripheries of the upper cover plate body and the lower cover plate body are coated with the coating rings; a plurality of supporting rods A are arranged at the communication part of the tube hole of the input tube part and the cavity; the upper cover plate body is provided with a plurality of arc-shaped bulges A, circular arc-shaped grooves A and radial grooves A, which are formed in the inner wall of the cavity; a plurality of supporting rods B are arranged at the communication part of the tube hole of the output tube part and the cavity; the lower cover plate body is provided with a plurality of arc-shaped bulges B, circular arc-shaped grooves B and radial grooves B, which are formed in the inner wall of the cavity; a plurality of reinforcing ribs are arranged at the bottom of the lower cover plate body. By adopting technical scheme of the invention, the filtering membrane is less susceptible to damage, the filter is less susceptible to blockage, and the filtering speed is stable and high.

The invention discloses an automatic filtration injector, which comprises an injector and a filtration injection needle, wherein the injection needle consists of a needle tube and needle holders; the needle tube is arranged at the front end of an upper needle holder; the back end of a lower needle holder is connected to the taper head of the injector; the front end of the lower needle seat is combined with the upper needle seat, so that a liquid suction inlet and an injection outlet are formed; a check valve is arranged on the lower needle holder, and is opened in the liquid suction direction of the liquid suction inlet and the injection direction of the injection outlet; and a filter is arranged at the liquid suction inlet. Filtration and injection processes are carried out automatically without replacing a needle head. The injector is simple in overall structure, convenient to operate, safe, reliable, low in cost and disposable, and the content of medicament impurities and the risk of cross infection can be lowered effectively.

The invention relates to a sulfydryl-amidogen modified bifunctional mesoporous silicon material synthesized by a copolycondensation method. The material can simultaneously adsorb two types of inorganic arsenic forms, namely pentavalent arsenic (As (V)) and trivalent arsenic (As (III)) under the condition of weak acid. The prepared material is put in a syringe filter and is fixed by virtue of a filter membrane so as to be made into a simple solid-phase extraction head. When solid-phase extraction is carried out, a sample solution passes through the extraction head, and the two types of inorganic arsenics in the solution are adsorbed by the material at the time; then a strategy of stage elution is adopted: the adsorbed As (V) is eluted with dilute nitric acid and collected to determine, then the adsorbed As (III) is eluted with a nitric acid / potassium iodate solution and collected to be measured, and therefore the contents of As (V) and As (III) in the sample solution are obtained. Compared with other solid-phase extraction methods, the method has the advantage that the sample only needs once extraction so that the contents of As (V) and As (III) can be respectively obtained. In addition, a device is simple and convenient, and the sample pretreatment is easily and fast completed.