The present disclosure provides a zero-correlation linear cryptanalysis method, system, medium and electronic equipment, including the following steps: obtaining an adjustable block cipher to be analyzed; treating the obtained adjustable block cipher as a vector Boolean function, constructing plaintext, cipher The key sum adjusts the mapping relationship with the vector Boolean function, and sets the linear approximation expression of the vector Boolean function; searches for a linear approximation that makes the correlation value of the linear approximation expression zero, and distinguishes according to the obtained linear approximation, that is, zero correlation The device is converted into an integral distinguisher to judge whether the key used for reverse decryption is correct; wherein, the correlation of the zero-correlation linear approximation approximation expression is obtained by traversing all possible values of the plaintext, key and adjustment; in this disclosure, the plaintext , keys and adjustments are treated equally, realizing fast and accurate search for linear approximation, can determine the accuracy of keys more quickly, reduce the complexity of decryption, and improve the success rate of integral attacks.