49results about How to "Increase activity time" patented technology

The field of the invention is that of oral medicaments or pharmaceutical compositions, in particular of the type including one or more active principles. The aim of the invention is to provide an improved oral medicament to be administered in one or several daily doses and enabling the modified release of active principles (in particular of one active principle), whereby the prophylactic and therapeutic effectiveness of said medicament is improved. This aim is achieved by the oral multimicrocapsule galenic form according to the invention, in which the active principle release is controlled by a dual release trigger mechanism: “time-dependent trigger” and “pH-dependent trigger”. Said medicament includes microcapsules providing the modified release of the active principle, each comprising a core containing

This invention provides a multi-frac composite perforation device having (i) a gun body having an outer wall, (ii) an inner gunpowder box between adjacent perforating charges in the charge frame 1 of said perforation device, and (iii) a structure for gunpowder charge with an outer gunpowder box 4 attached to an outer wall of the charge frame 1, the gun body has a pressure releasing structure corresponding to a closed end of the perforating charge. This invention further provides a method of using the multi-frac composite perforating device to fracture a formation and the choice of gunpowders and gun body thickness with regards to the pressure required for fracturing a formation.

A combined fracturing and perforating method and device for oil and gas well are disclosed. The method utilizes an explosion of a perforating charge (5) in a combined fracturing perforator to ignite primary gunpowder in the perforator, and burning of the primary gunpowder ignites secondary gunpowder in the perforator. The body of the perforating gun in the combined fracturing and perforating device is provided with pressure releasing hole (8) which is directly facing the jet direction of said perforating charge, and sealing sheet (9) is arranged on said pressure releasing hole (8). Inner gunpowder box (6), which contains the primary gunpowder, and outer gunpowder box (7), which contains the secondary gunpowder, are mounted on the cylindrical charge frame (4).

The invention provides a man-machine interaction control method and application thereof. A user controls a self-role in a virtual environment to implement corresponding virtual permissible action by implementing user permissible micro-action. The method includes the steps: 1) creating the self-role in a virtual world; 2) executing the micro-action by the user without leaving the position of the body of the user; 3) tracking and identifying the micro-action executed by the user with the body not leaving the position of the user when the user executes optional micro-action; and 4) amplifying the self-role to execute the micro-action of the user. By the aid of an 'action amplifying system', the user can realize all functions or abilities endowed by all virtual worlds without displacement of the body or only by tiny displacement of the body, the user stays at the same control position in the whole process of the virtual worlds, moving parts of the user are consistent with those of persons in the virtual worlds, and the user easily uses the method.

A method for building a water maze spatial learning and memory model for tree shrews includes: screening tree shrews before test, preparing experimental facilities, carrying out experimental operations and determining model building indexes. The model building indexes determined in the method includes that accuracy is more than 90% in a place navigation test, and an average latency between 20s and 25s serves as a standard of a spatial learning model built by a tree shrew in the water maze test; and in a space exploration test, a spatial memory model built by the tree shrew in the water maze test is determined according to significant difference of ratio of time spent in the target quadrant and crossing times before and after training.

Methods of inhibiting HSP70 proteins, agents causing the inhibition of HSP70 proteins, and the effects of such inhibition on cell proliferation. Anti-microbial agents comprising small molecules, or pharmaceutical salts thereof, disclosed herein and further methods of use thereof are also disclosed. The disclosed small molecules, or pharmaceutical salts thereof, are effective in inhibiting microbial chaperone activity in microbes, such as homologs of HSP70. The disclosed small molecules, or pharmaceutical salts thereof, are also effective for the therapeutic treatment of cancer.

Techniques are addressed for providing young children with an art experience in which opportunities to misuse art supplies, such as crayons, markers and the like are substantially reduced. To such ends, an art supply system is provided in which selectively enabled art supplies are automatically enabled so that they are useable only within a compliant usage zone, such as within a predetermined distance of an acceptable work surface.

A combined fracturing and perforating method and device for oil and gas well are disclosed. The method utilizes an explosion of a perforating charge (5) in a combined fracturing perforator to ignite primary gunpowder in the perforator, and burning of the primary gunpowder ignites secondary gunpowder in the perforator. The body of the perforating gun in the combined fracturing and perforating device is provided with pressure releasing hole (8) which is directly facing the jet direction of said perforating charge, and sealing sheet (9) is arranged on said pressure releasing hole (8). Inner gunpowder box (6), which contains the primary gunpowder, and outer gunpowder box (7), which contains the secondary gunpowder, are mounted on the cylindrical charge frame (4).

A plasma source is provided. The plasma source includes at least three hollow cathodes, including a first hollow cathode, a second hollow cathode, and a third hollow cathode, each hollow cathode having a plasma exit region. The plasma source includes a source of power capable of producing multiple output waves, including a first output wave, a second output wave, and a third output wave, wherein the first output wave and the second output wave are out of phase, the second output wave and the third output wave are out of phase, and the first output wave and the third output wave are out of phase. Each hollow cathode is electrically connected to the source of power such that the first hollow cathode is electrically connected to the first output wave, the second hollow cathode is electrically connected to the second output wave, and the third hollow cathode is electrically connected to the third output wave. Electrical current flows between the at least three hollow cathodes that are out of electrical phase. The plasma source is capable of generating a plasma between the hollow cathodes.

The invention provides a method for controlling human-machine interaction and an application thereof. A user controls a self-character in a virtual environment to implement a corresponding virtual permissible action by performing a user permissible micro-action. The method comprises the following steps of: (1) creating a self-character in a virtual world; (2) enabling the user to perform a micro-action without leaving the position of the user; (3) tracing and identifying the performance of the micro-action by the user, and enable the user to perform any micro-action without leaving the position of the user; and (4) amplifying the self-character to execute the micro-action of the user. Due to the adoption of an action amplifying system introduced by the invention, the user can realize all functions or capabilities given by the entire virtual world without moving or by moving slightly, the user can keep at the same operating position in the entire virtual world, meanwhile the consistence of the moving part of the user with a character moving part in the virtual world can be realized conveniently, and the user can comprehend easily.

The invention relates to a litopenaeus vannamei culture method based on a microorganism-aquatic plant-marine fish multistage biological system, wherein high-density culture without changing water canbe achieved. According to the method, a microorganism, aquatic plant and fish multistage culture system is built, staged high-density culture of litopenaeus vannamei is implemented, two stages includea high-density culture stage of a young litopenaeus vannamei pond and an amplification culture stage of a large pond in the development period of young litopenaeus vannamei, the survival rate and theyield of the litopenaeus vannamei are increased, and ecological benefits, economic benefits, resource conservation and the like in a culture system are remarkable.

The invention discloses a culture method for reducing a disease incidence of penaeus vannamei. The method comprises the following steps: step 1, building a pond and treating the pond: arranging an aerator, a bait throwing device and a water inlet and a water outlet in the pond, sterilizing and disinfecting the pond before cultivation, fertilizing bottom mud, and planting waterweeds at the bottom of the pond; step 2, performing throwing: throwing the disinfected penaeus vannamei larvae and ctenopharyngodon idellus fry; step 3, performing feed management: performing feed feeding for 3-4 times per day; and step 4, preventing diseases: inspecting the pond every day, observing water quality and activities of fishes and the penaeus vannamei, timely changing water and performing oxygenation, andapplying a mixed preparation of a traditional Chinese herbal medicine liquid and probiotics for 3-5 times per month. The invention provides the culture method for reducing the disease incidence of thepenaeus vannamei. According to the invention, through optimizing culture technologies, the residual feed is less, the resource utilization rate is high, the water exchange amount is less, and therefore outbreaks and epidemics of bacterial diseases and viral diseases are effectively inhibited; and the disease incidence of the penaeus vannamei is low, and the survival rate is high, so that the development of a culture industry of the penaeus vannamei is effectively promoted.

A method of producing a plasma is provided. The method includes providing at least three hollow cathodes, including a first hollow cathode, a second hollow cathode, and a third hollow cathode. Each hollow cathode has a plasma exit region. The method further includes providing a source of power capable of producing multiple output waves, including a first output wave, a second output wave, and a third output wave. The first output wave and the second output wave are out of phase, the second output wave and the third output wave are out of phase, and the first output wave and the third output wave are out of phase. Each hollow cathode is electrically connected to the source of power such that the first hollow cathode is electrically connected to the first output wave, the second hollow cathode is electrically connected to the second output wave, and the third hollow cathode is electrically connected to the third output wave. Electrical current flows between the at least three hollow cathodes that are out of electrical phase. A plasma is generated between the hollow cathodes.

This invention provides a structure for gunpowder charge in multi-frac composite perforation devices that is easy to assemble and transport while the charge volume of gunpowder is increased. In one embodiment of the present invention, an triplet outer gunpowder box is attached onto the outer wall of the charge frame and comprises one middle gunpowder box charged with gunpowder of certain burning rate, and two side-hung gunpowder boxes charged with gunpowder of another burning rate. The two side-hung gunpowder boxes are separately located on the two sides of the middle gunpowder box and are connected with the middle gunpowder box as a unit. The middle gunpowder box is located at a position corresponding to the perforating charge, and has an inner groove for orienting the perforating charge and a through hole through which the jet flow passes.

The present invention belongs to the field of the application of genetic engineering and gene function, and it is directed to a new medical use of the gene encoding the recombinant soluble tumor necrosis factor α receptor (HusTNFR). The present invention made intervention to fulminant hepatic failure in mice by use of the long-acting recombinant human soluble tumor necrosis factor α receptor and the classic animal models of acute and sub-acute hepatic failure. The results showed that the long-acting soluble tumor necrosis factor αreceptor of the present invention has a half-life extended more than 10 times, and it significantly decreased the mortality of model animals and has superior therapeutic effect for the treatment and / or prophylaxis of acute and sub-acute hepatic failure in model animals. These receptors have a noticeable therapeutic effect for the treatment and / or prophylaxis of acute and sub-acute hepatic failure in comparison with the non-long-acting HusTNFR.

The invention discloses a sofa with nursing effect, which comprises a sofa base, a controller, sofa handrails, a sofa back cushion, a seat cushion, an electronic blood pressure meter, a baffle plate and a pull rod, wherein the sofa handrails are arranged on the sofa base, pull springs are arranged in the sofa handrails, pull rings are arranged on the pull springs, the electronic blood pressure meter is arranged on the sofa handrail which is arranged on the right side, the controller is arranged on the sofa handrails, the sofa back cushion is arranged on the sofa base through an adjusting base, the seat cushion is arranged on the sofa base, a heating device and a temperature sensor are arranged in the seat cushion, the baffle plate is arranged on the sofa base through the pull rod, the baffle plate is provided with pedals, and a care appliance box is arranged on the sofa base through slide rails. The sofa with nursing effect is simple in design and low in cost, has strength for achieving exercise of upper limbs and lower limbs, and has excellent nursing effects to bodies.

The invention discloses a sofa with a nursing function. The sofa comprises a sofa base, a controller, sofa armrests, a sofa back cushion, seat cushions, an electronic blood pressure measurement gauge, a baffle and pull rods, wherein the sofa armrests are mounted on the sofa base, tension springs are arranged in the sofa armrests, pull rings are mounted on the tension springs, the electronic blood pressure measurement gauge is mounted on the sofa armrest on the right side, the controller is mounted on one sofa armrest, the sofa back cushion is mounted on the sofa base through an adjusting device, the seat cushions are placed on the sofa base, heating devices and temperature sensors are arranged in the seat cushions, the baffle is mounted on the sofa base through the pull rods, foot pedals are arranged on the baffle, and a nursing device box is mounted on the sofa base through a sliding rail. The sofa is simple in design, lower in equipment cost, can exercise upper and lower limbs and has a good nursing effect on human bodies.

The invention discloses a crutch capable of deforming to a simple wheelchair. The crutch comprises a support base, a connecting rod and a handle in sequential connection from bottom to top, and also comprises a chair pad assembly connected with the connecting rod, wherein the chair pad assembly comprises a plurality of support rods which are unfolded in a fan shape and are of T shaped structures;each support rod comprises two fixing rods connected with the connecting rod and a free end; the center connecting point of the support rod is a rotating connecting point; the two fixing ends of the support rods are rotationally connected with the connecting rod, so that the support rods realize the support rod unfolding and contraction according to the 90-degree rotation from the vertical direction to the horizontal direction; the crutch also comprises a fan-shaped double-layer air pad. The crutch using the design can be converted into the wheelchair through the simple deformation; the movingrequirements of people with moving inconvenience or old people can be met at the same time; meanwhile, the wheelchair used for resting can be provided for people with moving inconvenience or old people at any time; the moving time can be prolonged for the people, so that the people are promoted to get well earlier.

A palm leaf extract is prepared by ultrasonic extracting pulverized palm leaf with ethanol, and establishing mouse depression model by chronic unpredictable stress to study the antidepressant effect of palm leaf extract. The results of sugar-water preference test, open-field test, novelty environment inhibition feeding test and hanging-tail behavior test showed that palm wood extract had obvious antidepressant effect, which provided a basis for clinical research.

The present invention relates to a washing method for textiles, which prevents the clothes to be washed from becoming disarranged, entangled or knotted by means of an intensive agitating cycle with asymmetric and symmetric agitating cycles in combination with soaking periods thereby achieving optimal washing with low water consumption.

Techniques are addressed for providing young children with an art experience in which opportunities to misuse art supplies, such as crayons, markers and the like are substantially reduced. To such ends, an art supply system is provided in which selectively enabled art supplies are automatically enabled so that they are useable only within a compliant usage zone, such as within a predetermined distance of an acceptable work surface.

The present invention relates to an air supply valve for filling chemical protective clothing with air. The present invention comprises: a valve body which includes a first flow path for receiving air of an air tank and a second flow path for receiving air of an air supply unit, has a discharge flow path connected with the first flow path and the second flow path so as to discharge the air of the flow paths, and fills the inside of the chemical protective clothing with the air by supplying, to the inside of the chemical protective clothing, the air discharged from the discharge flow path in the state where the valve body is fixed to the clothing; a socket for supplying the air of the air supply unit to the second flow path of the valve body; and a transfer switch for selectively switching a circulation path of the air by connecting the first flow path or the second flow path of the valve body with the discharging flow path in an alternating state. The present invention can selectively and conveniently switch the circulation path of the air according to the connected location of the air supply member since the first flow path and the second flow path of the valve body are alternately switchd through the transfer switch so as to be connected with the discharge flow path.

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating apoplexy, which comprises the following raw medicinal materials: artemisia anomala, radix puerariae, prepared radix polygoni multiflori, mentha leaf, radix bupleuri, cortex lycii radicis, rhizoma coptidis, fiveleaf gynostemma herb, pinellia ternate, radix aucklandiae, rhizoma gastrodiae, notopterygium root, manchurian wildginger, rhizoma anemarrhenae, scutellaria baicalensis, chaste berry, licorice root, Chinese angelica, sichuan paeonia lactiflora, radix paeoniae alba, rehmannia glutinosa, folium ginkgo, radix linderae, pseudo-ginseng, salvia miltiorrhiza bunge, p latycodon grandiflorum, cinnamomum cassia presel, divaricate saposhnikovia root, radix angelicae pubescentis, mobenda and common cnidium fruit. The invention has the advantages of strong drug effect, treatment of both principal and secondary aspect of disease, no toxic or side effect and high curative rate.

The invention discloses a sofa with a nursing effect. The sofa comprises a sofa base, a controller, sofa armrests, a sofa cushion, seat cushions, an electronic blood pressure measurement meter, a baffle and pulling rods, wherein the sofa armrests are installed on the sofa base, pulling springs are arranged inside the sofa armrests, pulling rings are arranged on the pulling springs, the electronic blood pressure measurement meter is installed on the sofa armrest on the right side, the controller is installed on the sofa armrest, the sofa cushion is arranged on the sofa base through an adjusting device, the seat cushions are placed on the sofa base, a heating device and a temperature sensor are arranged inside the seat cushion, the baffle is installed on the sofa base through the pulling rods and is provided with pedals, and a nursing tool is arranged on the sofa base through a sliding rail. According to the present invention, the sofa has advantages of simple design and low equipment cost, can achieve the exercising of the upper limbs and the lower limbs, and has the good nursing effect to the body.

Compositions, methods and kits are provided comprising (a) a therapeutically effective amount of a DnaK inhibitor; and (b) a therapeutically effective amount of a known antibacterial agent. Such compositions, methods and kits are useful in the treatment of various bacterial infections.

The invention discloses a preparation device and method of boiling-resistant old hen powder seasoning for hotpot, and relates to the technical field of seasoning processing. The preparation device comprises a preparation tank body, supporting legs are fixedly installed at the bottom of the preparation tank body, a discharging port is formed in the bottom of the preparation tank body, and a granule preparation mechanism is arranged at the top of the preparation tank body; a granule drying mechanism is arranged in an inner cavity of the preparation tank body, and a steam treatment mechanism is arranged at the top of the preparation tank body. By controlling an air pump body to operate, an inner cavity of a raw material pushing box can be inflated through a sealed conveying pipe, so that the pressure in the inner cavity of the raw material pushing box is increased, and a sliding plate is promoted to push a prototype material out of a forming hole; a motor body is driven to drive a blade to rotate, so that the function of quickly processing a prototype material into particles is realized; therefore, the problem that the processing efficiency of granulation through manual extrusion is low is solved, and the overall efficiency of seasoning preparation is improved.

The invention relates to the Chinese medicinal fields, particularly a Chinese medicinal composition for treating apoplexy which is prepared from raw Chinese medicinal including angelica, chuanshao, white peony root, rehmanniae vaporata, ginkgo biloba, combined spicebush, panax notoginseng, salvia, balloonflower, guangui, radix sileris, pubescent angelica, moben, frutus cnidii, Junefrost, gegen, radix polygonum multiflorum, corn mint leaf, bupleurum, cortex lycii radicis, coptis, gynostemma pentaphylla grass, pinellia ternate, radix auckladiae, rhizoma gastrodiae, notopterygium root, asarum, anemarrhena, huangqin, viter rotundifolia and glycyrrhiza. The Chinese medicinal composition has advantages of stronger efficacy, treating both principal and secondary aspect of disease, no side effect and high cure rate.