84 results about "Dual release" patented technology

Disclosed is a controlled-release microparticle: including a matrix comprising a pharmacologically active component; and a controlled-release layer comprising a substance which forms a controlled-release stratum on the matrix. The disclosed controlled-release microparticle not only allows effective dual release control of a drug but can also exhibit outstanding dissolution characteristics even when a small amount of coating substance is used.

A method and system for delivering drug includes a first set of holes filled with a first formulation of the drug and a second set of holes filled with a second formulation of the same drug. This dual formulation or dual release kinetic system allows the creation of specifically tailored release kinetics by summation of multiple release kinetics.

The invention relates to a stubborn stain decomposer and application thereof. The stubborn stain decomposer is particularly applicable to the decomposition of hair-dyeing stains on towels, clothes or textiles. The invention invents the stubborn stain decomposer, which belongs to a dual-release washing agent, dye, grease and protein on the towels are fast removed through fast-release parts containing organized enzymes, other stains on the towels are removed through slow-release parts containing polyethenoxy ether compounds, and plant saponin and plant volatile oil are also contained in the slow-release parts, so the stain removing capability and the antibacterium capability are enhanced.

Disclosed is a housing assembly for twin latching mechanisms. The housing assembly includes two handles that can be pivoted to separately unlatch two belt connectors. The latching mechanisms are positioned within the housing such that when the handles are pivoted upwardly, their leading edges engage plunger mechanisms associated with the latching mechanisms. By engaging the plunger mechanisms, individual latches are disengaged and the associated belt connectors are ejected. A flange interconnects the two handles such that one or both handles are pivoted depending upon which handle is lifted by the operator. The housing provides a secure enclosure for the latch mechanisms and also shields the working components from the environment.

The field of the invention is that of oral medicaments or pharmaceutical compositions, in particular of the type including one or more active principles. The aim of the invention is to provide an improved oral medicament to be administered in one or several daily doses and enabling the modified release of active principles (in particular of one active principle), whereby the prophylactic and therapeutic effectiveness of said medicament is improved. This aim is achieved by the oral multimicrocapsule galenic form according to the invention, in which the active principle release is controlled by a dual release trigger mechanism: “time-dependent trigger” and “pH-dependent trigger”. Said medicament includes microcapsules providing the modified release of the active principle, each comprising a core containing

Orally deliverable dual-release pharmaceutical suspensions, having a first portion comprising an immediate release form of the active in the solution form or granules or suspended form in the vehicle/medium preferably in the solution form and a second portion comprising a sustained-release form of active in the form of microgranules/microparticles suspended in the immediate release fraction of the solulabilised active agent which comprise a core and at least one coat suitable for liquid dosage forms for the administration of the active ingredients, wherein the core comprises at least one active agent(s) or its pharmaceutically acceptable salts, derivatives, isomers, polymorphs, solvates, hydrates, analogues, enantiomers, tautomeric forms or mixtures thereof; optionally at least one water insoluble, and optionally one or more pharmaceutically acceptable excipient(s); and at least one coat comprising at least one pH independent water-insoluble polymer(s) along with one or more pharmaceutically acceptable excipient(s). This coated microparticles and solution of the active agent in the vehicle ensures a dual release profile i.e. immediate release profile as well as predetermined sustained release profile of the active agent and also ensures maintenance of said release profile over time. The present invention can be administered either in the form of ready to use suspension or in the form of powder ready for reconstitution. Further, this invention provides process of preparation of such suspensions and method of using them.

The invention belongs to the technical field of oilfield chemistry, and in particular relates to a preparation method of a controllable long-acting slow-release scale inhibitor capsule. According to the eight steps of loading a scale inhibitor, performing kneading and drying, preparing a carboxymethyl cellulose solution, uniformly mixing a polymer and a loaded sample, preparing a capsule, preparing a polyvinyl alcohol dispersion, coating a shell layer on the outer wall of the capsule, and performing drying, the scale inhibitor and an inorganic nano carrier which is one of the slow-release components are assembled into a homogeneous whole body in the form of a solid solution, and the outside is coated with a controllable soluble crosslinking polymer. When the polymer dissolves in an environmental medium, an active substance is gradually released. By the dual release control mechanism of the polymer dissolution and the scale inhibitor desorption from the inorganic nano carrier, the controllable slow release of the scale inhibitor in a wellbore is achieved, and thus the protective effect on the wellbore is prolonged.

Disclosed is a restraint system for a vehicle. A crewmember or occupant is interconnected to the restraint system by way of a strap. The strap has two separate and independently operable release mechanisms. The strap permits the occupant to be either manually or automatically released from the associated restraint. The restraint can be mounted within any of a variety of land, sea, air, or space based vehicles. In one non-limiting embodiment, the first release mechanism is automatically activated in response to a triggering event and the second release mechanism is manually activated by the occupant pulling on a lanyard.

The invention discloses design and application of a drug and fluorescence dual-release system based on glutathione and photo-stimulation and designs and synthesizes a glutathione and photo-stimulation-based drug and fluorescence dual-release system. The glutathione and photo-stimulation-based drug and fluorescence dual-release system takes target molecules released by the drug of glutathione and 2, 4-dinitrobenzene sulfonyl chloride as response groups. Detection of the fluorescence performance of a prodrug (CM-2) shows that the prodrug (CM-2) can well respond to the glutathione to release fluorescence; meanwhile, compared with other photosensitive drugs, the prodrug is higher in stability and targeting property; measurement of antineoplastic activity research through an MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) method shows that the antineoplastic activity of the compound (CM-2) is higher than that of chlorambucil and accordingly shows that the targeting property of the compound (CM-2) is higher than that of the chlorambucil; the drug ingestion situation of cells is researched according to the fluorescence characteristics of coumarins, and experimental results show that the prodrug can be ingested by cells. The glutathione and photo-stimulation-based drug and fluorescence dual-release system provides an effective research tool for drug release of cell research.

The invention discloses an efficient fertilizer beneficial to increasing the carotenoid content of carrots. The efficient fertilizer is prepared from selenium-containing chitosan oligosaccharide, pyroligneous acid, succinylcholine, indolebutyric acid, table vinegar, sodium nitrophenol, medical stone powder, garlic powder, plant ash, casein, waterborne polyurethane emulsion, purple perilla seed cake micropowder, pepper leaves, acorus calamus leaves, zinc gluconate, casein, alginate fibers, ferric citrate, carboxymethyl cellulose sodium, decomposed rape seed cakes, wood chips, decomposed castor cakes, liquid paraffin, pentaerythritol, melatonin, carotenoid, a proper amount of slightly-alkaline small-molecular-group magnetized water and the like by weight. The adopted functional melatonin and carotenoid can assist in improving the quality of carrots, and meanwhile the fertilizer prepared from a nutrient solution, main ingredients prepared from compost and outer-layer coating liquid for coating in cooperation has the advantages that dual release is achieved, rich nutrients are provided, and efficient cultivation of high-quality carrots is achieved.

The invention discloses a preparation method of high-load long-acting slow-release scale inhibition particles, and belongs to the field of oilfield chemistry. A scale inhibitor and an inorganic nano-carrier serving as one of slow-release components are assembled into a homogeneous whole in the form of a solid solution, and the homogeneous whole is coated with a layer of controllable swelling polymer. When the polymer swells in an environmental medium, the scale inhibitor is slowly released. A dual-release control mechanism of polymer swelling and desorption of the scale inhibitor from the inorganic nano-carrier is utilized, so that the scale inhibitor is slowly released in the wellbore, and the protection effect on the wellbore is prolonged.

The invention discloses a tie-back barrel device capable of rotating into a well. The device comprises a torque transfer unit, a dual releasing unit and a tie-back unit. The torque transfer unit is composed of an upward lifting barrel, a sliding barrel, a shearing pin, a spring, slips, a blocking baffle and a tie-back barrel. An inner cavity with the area difference is arranged between the sliding barrel and the upward lifting barrel. A pressure transfer hole is formed in the upward lifting baffle. An annular groove is formed in the outer side of the sliding barrel. The upper portion of the sliding barrel is provided with a retaining mechanism. The dual releasing unit comprises a hydraulic releasing unit body and a mechanical back-off releasing unit body and is composed of a back-off barrel, a ball base, a clamping key, a separation barrel, a sliding sleeve, a pin and a clamping ring. The separation barrel and the upward lifting barrel are connected through a screw. The sliding sleeve is arranged on the external circle portion of the separation barrel. The front portion of the sliding sleeve is provided with a threaded hole and a groove. The back-off barrel and the separation barrel are matched through the clamping key and an inserting key. The tie-back unit comprises a tie-back barrel and an inserting-back barrel. The tie-back barrel device is one completion pipe string component, is connected to an oil pipe or drill rod, and can be used in a direct well or inclined well.

A dual release lanyard connector includes first and second lanyard rings coupleable to first and second lanyard cables, a coupling sleeve coupled to the first lanyard ring and movable between a first position and a second position, and a locking ring configured to engage the coupling sleeve and movable between the first position and the second position, the locking ring having a first ring groove. A two-piece housing of the lanyard connector includes a plug housing with first and second plug housing grooves and a secondary housing coupled to the second lanyard ring and having a secondary housing groove, the secondary housing movable between a third position and a fourth position. The secondary housing is configured to engage the coupling sleeve such that movement of the secondary housing to the fourth position causes a corresponding movement of the coupling sleeve and locking ring to the second position.

The invention discloses an efficient fertilizer for reducing cycloalliin to form the gentle onion taste. The fertilizer is prepared from, by weight, full-fat rice bran, soybean oil, manganese sulfate, filter sludge in sugar refineries, clamshell powder, oil shale ash, soybean milk residues, brewer's grains, egg shell powder, pepper leaf ash, activated zinc-rich yeast, urea, bagasse, selenium-rich tea residues, camellia honey, citric acid, activated bone meal, amino acid raw powder, peanut bud powder, acid activated tea leaf ash, maleic anhydride, ammonium paramolybdate, octadecanol, xanthan gum, gelatinized starch slurry, an appropriate amount of nano-grain-size acidized small-molecular activated water and an appropriate amount of water. Functional compounds can assist in improving acid-base properties in onion cells, and the effect of regulating the synthesis speed of cycloalliin in onions to a certain degree is achieved; meanwhile, the fertilizer prepared by matching the functional compounds with a nutrient solution, main materials of compost preparation and outer layer envelope liquid and conducting enveloping can achieve dual release, has abundant nutrition and has the advantages that the taste of onions is improved and efficient cultivation is achieved.

The invention discloses a lightning protection type power extension cord comprising a power line, a housing, a lightning protection module, and a plurality of power output sockets. The lightning protection module and the power output sockets are assembled to a housing panel; and the power line is connected with the lightning protection module and the power output sockets inside the housing. The lightning protection module consists of piezoresistors, a gas discharge tube, an LED tube, a current-limiting resistor, a PCB, temperature fuses, phosphorized copper spring sheets and low-temperature solder points. The piezoresistors and the gas discharge tube form a lightning protection loop; the phosphorized copper spring sheets, the low-temperature solder points, and the low-temperature solder points form a dual release unit and are connected in series into the lightning protection loop; the lightning protection module is connected in parallel between a power line live wire, a zero line, and a ground wire; the dual release unit enables the lightning protection loop to bounce off when the piezoresistors are heated; and the LED tube is connected in series with the current-limiting resistor and then is connected to the piezoresistor sides of the two low-temperature solder points. With the lightning protection type power extension cord, lightning protection of external equipment can be realized and the lightning protection device can also be protected safely.

The invention discloses an efficient micromolecular coated fertilizer beneficial to increasing the content of anthocyanin in purple sweet potatoes. The efficient micromolecular coated fertilizer is prepared from fermented soybean meal protein powder, fermented rice bran meal, decomposed woody plant powder, silicate bactericide, aedelforsite, pinewood-based biomass charcoal, fermented burdock residue powder, fermented Chinese cabbage residues, starch aluminum octenylsuccinate, amino-oligosaccharin, melatonin, sodium diethylhexyl sulfosuccinate, oleum fructus bruceae, fermented wheat bran, cured tea seed meal, dehydrated vegetable micropowder, collagen powder, prohexadione calcium, ammonium citrate, jasmonic acid methyl ester, phenylalanine, a proper amount of oxygen-enriched alkaline magnetized water and the like by weight. Functional micromolecular compounds containing ammonium citrate, jasmonic acid methyl ester, phenylalanine and melatonin are adopted in cooperation with a nutrient solution, main ingredients prepared from compost and outer-layer coating liquid for coating to prepare the fertilizer, so that the fertilizer has the advantages that dual release is achieved, rich nutrients are provided, the content of anthocyanin in purple sweet potatoes can be increased, and high-quality efficient cultivation of purple sweet potatoes can be achieved.