The invention discloses a minimally invasive surgery navigation system for spinal surgery, and relates to the technical field of medical treatment. The minimally invasive surgery navigation system forspinal surgery comprises a preoperative three-dimensional C arm, a two-dimensional O arm or a C arm scanning module, and the output end of the preoperative three-dimensional C arm, the two-dimensional O arm or the C arm scanning module is electrically connected with the input end of a graphic image signal conversion module. According to the minimally invasive surgery navigation system for spine surgery, a surgery is completed through the preoperative three-dimensional C arm, the two-dimensional O arm or the C arm scanning module, the graphic image signal conversion module, a two-dimensional skeleton data processing to three-dimensional module (or a three-dimensional skeleton model noise reduction module), a three-dimensional skeleton data storage module, a preoperative CT scanning and MRIscanning module, etc., so as to solve the problem that the operation plan making efficiency of doctors is affected to a certain extent due to the fact that the prior operation navigation system can only depend on computer assistance to form a data scanning model, and the multiple doctors cannot visually and directly observe, discuss and make operation plans in multiple aspects after correspondingmodels are fixed in a hand-held mode.