130 results about "Dose adjustment" patented technology

The invention discloses a dose-adjustable automatic injection pen, comprising: a pen shell assembly comprising a pen shell, a rotatable knob and a pushable button; the dose adjusting assembly is linked with the knob and is used for increasing the set dose when the knob rotates towards the first direction and reducing the set dose when the knob rotates towards the second direction; the injection assembly is linked with the key and is used for realizing injection when the key is pressed; the clutch is connected between the dose adjusting assembly and the injection assembly and has a first position state and a second position state, when the key is not pressed down, the clutch is in the first position state, the clutch and the pen shell are matched for limiting, and the position of the injection assembly is kept unchanged; when the key is pressed down, the clutch is in a second position state, the clutch is disengaged from the pen shell, and the injection assembly can be used for injection. When the clutch is in the first position state, the clutch is matched with the pen shell for limiting, so that the position of the injection assembly is kept unchanged, no injection action is generated when the dosage is adjusted, and the injection precision can be improved.

The invention relates to the technical field of remote medical monitoring, in particular to a medical patient remote monitoring system which comprises a health monitoring module, a disease course prediction module, a physiological regulation module, a medicine management module, a behavior analysis module, a therapy customization module, a dose adjustment module and a system comprehensive management module. According to the invention, accurate physiological monitoring is realized through a data fusion algorithm and a noise filtering technology, the accuracy and reliability of data are ensured, the recurrent neural network model can provide more accurate disease development trend analysis, early diagnosis and timely intervention are facilitated, and the accuracy and reliability of the system are improved. A self-adaptive control algorithm and a biological feedback technology enable a patient to more effectively adjust the physiological state by themselves, the treatment initiative is improved, and the safety and effectiveness of drug treatment are improved through a mode recognition algorithm and drug interaction analysis of drug management. Through deep data mining and personalized treatment strategies of the behavior analysis module and the therapy customization module, a more comprehensive and customized treatment scheme is provided for the patient.

An injection mechanism (1) capable of adjusting injection dose, and an injection syringe. In the injection mechanism (1), an injection push rod (80), and an injection dose adjustment assembly (1a) and a clutch control assembly (1b), which are connected to the injection push rod (80), are mounted in a housing (10); and in the injection dose adjustment assembly (1a), a tube (20) can be rotated by means of a dose adjustment knob (30) to drive a driving ring (50), such that an elastic assembly (40) generates an elastic force to drive the injection push rod (80).

The utility model discloses a quantitative dosing prefilled syringe, which comprises a syringe filled with a preset amount of liquid medicine in advance, and further comprises an injection push rod capable of being inserted into the syringe in an axial moving manner, and a dosage adjusting mechanism capable of being arranged on the syringe in an axial moving manner, the injection push rod is used for pushing liquid medicine in the injection cylinder to flow out, and the dosage adjusting mechanism is used for abutting against the limiting piece so as to limit the pushing stroke of the injection push rod. Thus, when a medical worker needs to inject a small dose at a time, the medical worker only needs to adjust the axial position of the dose adjusting mechanism according to the target axial distance corresponding to the target injection dose, then the injection push rod is pressed to start injection till the limiting piece abuts against the dose adjusting mechanism, and the maximum pushing stroke is achieved; therefore, it can be ensured that the actual injection dosage is equal to the target injection dosage, accurate injection of any dosage can be achieved, the requirement for accurate injection of single-time tiny dosage is met, and the treatment effect of a multi-injection administration mode is ensured.

The invention discloses an upper pen container assembly of an injection pen and the injection pen. A dose adjustment mechanism; a rotating wheel of the driving mechanism is located between the driving wheel and the power rod, an inner ring of the rotating wheel is in threaded connection with the screw, and an outer ring can rotate relative to the upper pen container, is in circumferential limiting connection with the sleeve and can move in the axis direction relative to the sleeve; the driving wheel and the sleeve are connected in a circumferential limiting manner, and during rotation, the driving wheel and the screw are limited in the circumferential direction, and the driving wheel and the bottle rack cover can rotate relatively; when the driving wheel and the sleeve rotate relatively, the bottle rack cover and the driving wheel are limited in the circumferential direction, and the driving wheel circumferentially limits the screw to rotate along with the rotating wheel. In the process of adjusting the dosage of injection medicine, the screw rod and the sleeve can guarantee the position stability under the supporting action of the power rod, the bottle rack cover and the rotating wheel, the rotating wheel can move in the direction close to the button in the axial direction, a distance is formed between the rotating wheel and the upper pen container in the axial direction, the stability of the position of the screw rod is further improved, and the service life is prolonged. And the rotation stability of the sleeve is improved.

The invention discloses an automatic injection pen with a replaceable pre-filling and sealing needle, which relates to the technical field of injection pens and comprises a lower pen shell, an upper pen shell, a pen cap, a button assembly and an automatic injection assembly. The upper pen shell is in threaded connection with the lower pen shell, the pen cap is clamped with the end of the lower pen shell, the button assembly comprises an inner nut in threaded connection with the upper pen shell, and the end of the inner nut is elastically connected with a button. A patient does not need to adjust the dosage before injection, injection operation is carried out by manually pushing the driving mechanism, automatic injection can be achieved under the action of the internal automatic injection assembly only by shifting the plug pin and pressing the button, operation is easy and convenient, and high practicability is achieved; according to the dosage, the liquid medicine in the pre-filling and sealing needle can be completely set according to the requirement of a patient, or the moving distance of the automatic injection assembly is set according to the requirement, so that quantitative injection to the patient is achieved.

The invention relates to the technical field of medical information, and discloses a dosage regulation and control data storage method and system based on multi-modal diagnosis and treatment data, and the method comprises the steps: obtaining historical diagnosis and treatment data and historical dosage data of a patient; matching the diagnosis result data with health diagnosis result data in the health diagnosis and treatment data, and matching the wearable device data with health wearable device data in the health diagnosis and treatment data; determining whether to adjust the historical dose data to obtain the current dose, and outputting a judgment result needing to be adjusted; and obtaining the adjusted dose data, and storing the diagnosis result data, the diagnosis result similarity, the wearable device data, the wearable data similarity, the historical dose data and the adjusted dose data into a dose adjustment unit in a patient database. According to the invention, multi-modal diagnosis and treatment data can be integrated and applied to dose regulation and control, and a complete medication decision data chain is constructed.

The invention relates to the technical field of medical treatment, and discloses an intelligent subject evaluation method based on multi-dimensional data, which comprises the following steps: acquiring the multi-dimensional data corresponding to a subject, inputting the multi-dimensional data into a pre-trained evaluation model, and acquiring an analysis report of the subject participating in clinical research, the multi-dimensional data comprises clinical symptoms, traditional Chinese and western medicine diagnosis, medication information and social background of the subject, and the analysis report comprises accuracy, compliance and risk; based on the analysis report, determining a corresponding group-entering suggestion and a treatment research scheme for each subject, the treatment research scheme including drug selection, dose adjustment and a follow-up plan; in the clinical research process, the latest research data are continuously obtained, and the analysis report and the treatment research scheme of the subject are adjusted based on the latest research data. The quality and effectiveness of clinical research can be improved.

A dose dial back mechanism of an energy storage injection pen, comprising: a support sleeve (1), which can rotate for dose setting and dose dial back, and can trigger an injection action; an energy storage sleeve (7), which is mounted outside the support sleeve (1) and is linked with the support sleeve (1) to achieve dose adjustment and execute an injection action according to the dose; a fixing gear (4), which is mounted at the front end of the energy storage sleeve (7) and can limit the rotation direction of the energy storage sleeve (7) after being engaged with the energy storage sleeve (7), such that when the fixing gear (4) is engaged with the energy storage sleeve (7), the energy storage sleeve (7) can rotate relative to the fixing gear (4) for dose setting or the energy storage sleeve (7) can drive the fixing gear (4) to rotate synchronously, and when the fixing gear (4) is disengaged from the energy storage sleeve (7), the energy storage sleeve (7) can rotate relative to the fixing gear (4) for dose dial back; and a transmission sleeve (6), which is configured to connect the support sleeve (1) and the energy storage sleeve (7) to achieve linkage, and can push away the fixing gear (4) to enable the fixing gear (4) to disengage from the energy storage sleeve (7). The dose dial back mechanism can achieve dose setting and dose dial back, and therefore can better adjust the dose.

The embodiment of the invention discloses a coprophilous fungus transplantation donor and acceptor dynamic matching method, device and equipment and a medium, and the method comprises the steps: responding to a donor and acceptor matching request, and obtaining the monitoring data of a to-be-matched acceptor after coprophilous fungus transplantation at the current preset sampling time; wherein the monitoring data after coprophilous fungus transplantation is determined on the basis of the coprophilous fungus transplantation operation of a to-be-matched receptor completed by the coprophilous fungus flora of any target donor, and the target donor is determined by performing adaptability matching on the gene feature information, the immune feature information and the clinical feature information of the to-be-matched receptor and a plurality of to-be-selected donors; and inputting monitoring data after coprophilous fungi transplantation into the transplantation strategy control model, outputting at least one of a donor switching strategy and a dose adjustment strategy for adjusting a to-be-matched receptor in a next time period, realizing comprehensive compatibility evaluation through multi-modal data integration, continuously optimizing a treatment scheme by means of a dynamic feedback mechanism, and improving the compatibility of the to-be-matched receptor. And the accuracy and adaptability of coprophilous fungus transplantation treatment are remarkably improved.

The invention relates to the technical field of medical instruments, in particular to a dose adjusting mechanism of an injection device and the injection device. A push rod part penetrates through a holding part and is in threaded connection with the holding part, a sound tooth part sleeves the push rod part and is in circumferential limiting connection with the push rod part, and the push rod part can move in the axial direction relative to the sound tooth part; one-way clamping grooves distributed in the circumferential direction are formed in the circumferential wall defining the containing cavity, the sound tooth part is located in the containing cavity, the sound tooth part is provided with an elastic clamping part, and the elastic clamping part is clamped into any one of the one-way clamping grooves; under the state that the push rod part is pressed, the push rod part can move in the axial direction and drive the sound tooth part to rotate synchronously under the action of the threads, so that the elastic clamping part slides along the peripheral wall defining the containing cavity to be clamped into one of the one-way clamping grooves in the front end. Axial control of the push rod part is converted into rotation control of the sound tooth part, rotation movement of the sound tooth part is discretized into fixed angle grading, the axial displacement of single-time grading of the push rod part is extremely small, and the small-dose injection requirement is met.

The invention relates to the technical field of intelligent medicine management, in particular to a medicine management method and system for old people. Based on the medication data of the old people, the absorption, distribution, metabolism and excretion processes of the medicine in the body are simulated, data analysis is carried out, and medicine dynamic analysis auxiliary information is generated. According to the method, numerical simulation is carried out on the absorption rate of the medicine in the body, so that medicine management can accurately calculate the behavior and effect of the medicine in the body according to the individual difference of old people, and medicine dosage adjustment is provided for old patients, especially for the situation that the dosage needs to be accurately controlled, such as management of anticoagulant medicine. Through accurate simulation, the health risk caused by improper dosage of the medicine can be reduced to the greatest extent. Secondly, by constructing a state and reward matrix, data-driven decision support is provided for selection and dose adjustment of each medicine;

The invention relates to the technical field of medical radiotherapy, in particular to a tumor radiotherapy dose optimization method based on a biomarker, which comprises the following steps: S1, biomarker collection: collecting tumor tissues and blood samples of a patient to obtain biomarker data related to a tumor radiotherapy effect; s2, data preprocessing: preprocessing the collected biomarker data; s3, constructing an initial radiotherapy dose optimization model: constructing the initial radiotherapy dose optimization model; s4, immune marker monitoring and dose adjustment: monitoring the change of the immune marker of the patient in real time, and dynamically adjusting the initial radiotherapy dose; and S5, treatment effect evaluation: comprehensively evaluating the treatment effect, and judging the effectiveness of the current treatment strategy. According to the invention, the accuracy and flexibility of radiotherapy are enhanced, the side effects of an immune system are effectively reduced, and immune regulation in the radiotherapy process is optimized.

The invention discloses a dose adjustment forward and reverse rotation structure of a medicine delivery device, and belongs to the technical field of medical instruments, the dose adjustment forward and reverse rotation structure comprises a knob, a ratchet seat, ratchet teeth, jumping teeth and an injection spring, the ratchet seat is connected with the ratchet teeth through a forward sound generating part, and the ratchet teeth and the jumping teeth are connected through a reverse sound generating part in a clutch mode; a first forward rotation cooperation part and a first reverse rotation cooperation part are arranged on the rotary knob, a second forward rotation cooperation part and a second reverse rotation cooperation part are arranged on the jumping teeth, and the injection spring is used for enabling the ratchet wheel teeth to be connected with the jumping teeth. The device is simple in structure, convenient to install and good in stability, the preset dosage can be adjusted through clockwise rotation, the force stored by the torsion spring can be clamped, the preset dosage can be reduced through anticlockwise rotation until the preset dosage returns to the zero position, forward rotation is converted into radial elastic tooth jumping meshing sound production, and reverse rotation is converted into axial tooth jumping meshing sound production.

The invention discloses a brain tumor disease treatment effect evaluation method, and belongs to the technical field of radiotherapy plan evaluation, and the method specifically comprises the steps: obtaining the brain multi-modal image data of a patient, and extracting a three-dimensional tumor region and a corresponding perfusion parameter; constructing a biological target region hierarchical structure containing a tumor overall region and an anoxic subregion; a relative hypoxia degree parameter is obtained by calculating the cerebral blood flow ratio of the hypoxia subregion to other regions of the tumor; historical treatment case data are deconstructed, and a dose-curative effect associated parameter set is established; training and outputting a dose adjustment strategy model for the hypoxia subregion; and generating a final radiotherapy dose planning scheme according to a dose adjustment value output by the model in combination with a clinical guide basic dose. Through a data-driven dose decision-making mechanism, the limitation of traditional uniform dose irradiation is overcome, so that an objective and reliable evaluation basis is provided for clinical selection and optimization of personalized treatment schemes.

The invention relates to the technical field of medical instruments, in particular to a dose adjusting mechanism of an injection device and the injection device. The push rod part penetrates through the holding part and is in threaded connection; the push rod part is sleeved with the transmission tooth part and limited in the circumferential direction, and the push rod part can move in the axial direction relative to the transmission tooth part. The transmission tooth part comprises a driven ratchet; the driving rod part can be switched from an initial position to an end position, and at the initial position, the driving ratchet and the driven ratchet are spaced in the axial direction and staggered by a preset angle in the circumferential direction; at the ending position, the driving ratchet is meshed with the driven ratchet, and the transmission tooth part rotates by an angle of one driving ratchet; the reset part drives the driving rod part to return to the initial position when the pressing force is released. The rotation angle of the transmission tooth part corresponds to the axial displacement of the push rod part, rotation of the transmission tooth part is discretized through one-by-one meshing of the driving ratchets and the driven ratchets, the single displacement of the push rod part is smaller, and the small-dose injection requirement is met.

The invention relates to the technical field of gastrointestinal tumor chemotherapy risk assessment, and particularly discloses a gastrointestinal tumor chemotherapy risk scoring model and a construction method thereof, and the method comprises the steps: obtaining the individualized feature data and basic physiological data of a historical patient, and constructing an individualized difference library with a unique ID, and a core influence library; the method comprises the following steps: standardizing and coding double-library data, synchronizing clinical data containing treatment effect codes, forming a data dictionary, acquiring and coding current gastrointestinal tumor patient data, and matching the data dictionary to judge individual difference abnormity; when the first data set is abnormal, constructing a first data set, screening core independent variables through Logistic regression, and constructing a scoring model by using an LSTM (Long Short Term Memory) model; when no abnormity exists, redundant codes are removed to obtain a second data set, and modeling is conducted through the same method. Through double-library linkage and scene-divided modeling, the three-level toxicity risk prediction precision is improved, data support is provided for clinical chemotherapy dose adjustment and toxicity prevention, and the risk of excessive treatment or insufficient treatment is reduced.

Disclosed are methods and compositions for testosterone replacement therapy, especially for use in administration to hypogonadal males. The methods and compositions employ an untitrated dose dosing regimen that does not require titration or dose adjustments and that can provide a therapeutically effective amount of a testosterone ester, such as a non-undecanoate testosterone ester, while avoiding unacceptably high testosterone levels.

The invention discloses an insulin injection pen, and belongs to the technical field of medical instruments. Comprising a main body shell, a connecting sleeve and a medicine bin, and the main body shell is connected with the medicine bin through the connecting sleeve; the adjusting mechanism comprises a dosage rotating cylinder and a transmission pipe, the dosage rotating cylinder is arranged in the main body shell and is in threaded connection with the main body shell, and the transmission pipe is arranged in the dosage rotating cylinder and is in clutch connection with the dosage rotating cylinder; the driving mechanism is arranged in the transmission pipe, and the driving mechanism is matched with the connecting sleeve to form an injection sound production structure; the insulin injection pen is switched from a dose adjusting state to an injection state through up-down separation and reunion of the transmission tube, and the insulin injection pen is injected and dosed through the driving mechanism. The connecting sleeve is made of a plastic part with high hardness, even if the medicament bottle gives reactive force to the driving mechanism during injection, the matching precision between the driving mechanism and the connecting sleeve is not affected, the reliability of the injection sound production structure is improved, and the problem of deformation or failure possibly occurring after the reactive force during long-term injection administration is avoided.

The present invention relates to the field of neural network technology, and specifically to a radiation dose adjustment system based on deep learning. The system includes: an image analysis module that scans and distinguishes the boundaries between tumors and normal tissues based on medical image data input, refines the size and shape of the tumor in the image through edge detection, extracts key features in the image through contrast enhancement, and generates tumor feature data. In the present invention, by distinguishing the boundaries between tumors and normal tissues and refining the features of the tumor in the image, the distribution of radiation doses is made more accurate and personalized. This detailed image analysis optimizes the treatment plan, ensures that the dose is concentrated in the lesion area, and reduces the impact on healthy tissues. In addition, the analysis of integrated clinical parameters enhances the understanding of the patient's radiation sensitivity and provides a treatment plan that better meets individual needs. This dose adjustment method based on in-depth analysis effectively adjusts the dose deviation in treatment by real-time monitoring of the execution effect of radiotherapy.

The invention provides a dose adjustment mechanism, and the subject of the invention is to reduce the influence of radiation in the dose adjustment mechanism of a radiation therapy device and suppress the occurrence of faults. The dose adjustment mechanism is characterized in that the dose adjustment mechanism (40) is provided with: an actuator (42) that is disposed apart from the radiation axis of the radiation therapy device (10) that irradiates radiation; and a grader (33) as an interference element that is moved in the vertical direction with respect to the radiation axis by the operation of an actuator (42) and that can switch between a state in which the grader is disposed on the radiation axis and a state in which the grader is not disposed on the radiation axis, the operation axis of the actuator (42) not intersecting the radiation axis.

This invention belongs to the field of acute lymphoblastic leukemia (ALL) technology and discloses an ALL scoring system. The system divides the entire treatment cycle into three major phases: induction remission, consolidation therapy, and maintenance therapy. Each phase is further subdivided into sub-phases, forming a two-tiered data acquisition architecture. During data collection, baseline data such as age and fusion genes are included, along with dynamic data such as the rate of MRD decline and drug exposure concentration. Simultaneously, anchor triggering mechanisms are set at different sub-phases, making the risk score more closely aligned with the patient's real-time condition and providing a more accurate reference for clinical treatment strategy selection. The feature adaptation module matches subtype-specific biomarkers and analyzes the interaction between rare subtypes and comorbidities. The matching module calls upon a three-dimensional protocol library to select standardized protocols for common subtypes, targeted protocols for rare subtypes, and dose adjustment or drug substitution protocols for patients with comorbidities, matching more suitable protocols for different patients.

The invention provides an individualized ovulation promoting scheme and gonadotropin initial dose prediction method based on multi-cycle time sequence modeling and related equipment, and is applied to the technical field of data processing. The method comprises the following steps: firstly, receiving multi-cycle clinical data and basic information of a target user for IVF / ICSI pregnancy-assisted patients, and eliminating unqualified samples to generate an initial data set; after SHAP screening features, training / test set division and SMOTE sample equalization are carried out, an initial model is constructed through a sliding window time sequence module and a multi-algorithm engine; a target model is generated through training and evaluation, and a COS scheme prediction signal and multi-period Gn dose adjustment information are generated in combination with hierarchical classification and weighted integration; calibration information is generated through clinical data verification, after target user information is subjected to standardization processing, an individualized COS scheme and a Gn initial dose are output through a target model, and multi-cycle dynamic accurate recommendation is achieved.

Most therapeutic treatments require dose adjustment after initial administration. Dosage adjustment is crucial to ensuring optimal safety and efficacy characteristics of the treatment. Gene therapy is inherently limited by the inability to adjust the dose after initial administration. This invention describes a genetic element capable of dose adjustment after the initial administration of gene therapy. The realization of dose adjustment allows for the replacement of multiple subcutaneous protein injection regimens with single-injection gene therapy, thereby improving pharmacokinetics, safety / efficacy characteristics, medication adherence, and reducing healthcare costs.

The invention discloses a medication management system with dose adjustment and a medication management method, and the method comprises the steps: enabling a doctor to give a medication scheme according to the illness state of a patient, update an individualized medication scheme according to a medication compliance report of the patient, and upload the medication scheme to a cloud server through the arrangement of a doctor terminal; and the cloud server sends a generated patient medication compliance report to a doctor end. The patient end confirms the medication scheme and generates a medication plan scheme according to the medication scheme; the intelligent medicine box controls the target medicine bin to discharge medicine according to the medicine taking scheme and the medicine taking plan scheme. Through cooperative work among the doctor end, the patient end and the intelligent medicine box, an individualized medicine taking scheme based on the doctor end is realized, and a patient can automatically execute a new medicine taking plan scheme and record medicine taking behaviors, so that dynamic dose control is realized in the medicine taking process of the patient, data interaction and medicine taking compliance feedback between the doctor and the patient are completed, and the patient can take medicine conveniently. The safety and the standardization of long-term medication of patients with chronic diseases are improved.

The invention relates to a firing device for a needleless injector and a needleless injection system. The needleless injector includes an injection chamber housing and a piston assembly. The launch device includes a support housing, a power push rod, and a dose adjustment device. The support housing is configured to be connectable to the injection chamber housing. The power push rod is configured to be connectable to the piston assembly and movable relative to the support housing. The dose adjusting device comprises a dose adjusting disc and a dose adjusting column, the dose adjusting disc is rotatably connected to the supporting shell, a plurality of dose grooves are formed in the dose adjusting disc, the depths of the dose grooves are different from one another, and the dose adjusting column is arranged on the power push rod and can move along with the power push rod. The dose adjusting column can change the movement stroke of the power push rod by being matched with different dose grooves. According to the needleless injection system of the scheme, a user can conveniently achieve injection of a preset dose.

An injection pen and a dose adjustment mechanism thereof. The dose adjustment mechanism comprises a power rod, a barrel body, a ball, a sleeve, and a torsion spring. The barrel body is sleeved outside the power rod. A spiral channel extending in an axial direction of the power rod is formed between an inner barrel wall of the barrel body and an outer rod wall of the power rod. The ball is rollably arranged in the spiral channel. The barrel body is relatively fixed to an upper pen barrel of the injection pen in a circumferential direction. The upper end of the torsion spring is relatively fixed to the upper pen barrel, and the lower end of the torsion spring is connected to the sleeve. The power rod can rotate relative to the barrel body under the action of external force. The sleeve is in circumferential limiting connection to the power rod. The sleeve is configured for being in transmission fit with a transmission mechanism of the injection pen. By means of structural optimization, the rolling smoothness of the ball in the dose adjustment mechanism can be ensured, so that the ball can be smoothly reset, thereby improving the reliability and safety during the use of the injection pen.

A variable dose fluid dispenser is described that may be used to deliver a dose of fluid to a subject. The fluid dispenser may comprise a dose adjustment method to control the volume of fluid dispensed. The fluid dispenser may comprise a plunger disposed within a chamber that translates in a linear direction relative to the chamber, translation moving the plunger: from a first position to a second position in a first direction causing fluid to be expelled from the chamber via the chamber outlet; and to a third position from the second position in a second opposite direction causing fluid to at least partly refill the chamber. Positional data from a sensor allows a controller to change the plunger positions to suit a dose to be administered.

This application discloses a feedback-optimized injection pen, relating to the field of medical device technology. The feedback-optimized injection pen includes a pen body, an adjustment mechanism, and an injection mechanism. The pen body includes a pen body with an outer cylinder and an inner cylinder, with a feedback rib on the outer side of the inner cylinder. The adjustment mechanism includes a dose hub, the outer side of which is threaded into the outer cylinder. The dose hub has a spring arm, which contacts the feedback rib to generate feedback when the dose hub rotates. The injection mechanism and adjustment mechanism have both coupled and decoupled states. When the injection mechanism is coupled to the adjustment mechanism, the injection mechanism pushes the liquid medication from the vial container under the action of the adjustment mechanism. This feedback-optimized injection pen, through its double-cylinder design, strengthens the assembly relationship with the dose hub and generates precise adjustment feedback during dose adjustment through the contact between the spring arm and the feedback rib, thereby improving the accuracy of dose setting and the reliability of the injection pen.

An assembly and method for housing and securing exposed dose adjustment control mechanisms of medical devices used to administer various medical therapies, is provided. In an exemplary embodiment, the inventive assembly and method serve to house and secure exposed dose adjustment control mechanisms of oxygen concentrators used to provide oxygen therapy. The inventive assembly, which securely encloses a dose adjustment control mechanism, permitting access only to select individuals, is made up of a cup-shaped hollow member having a through-hole in a distal wall, and a lid. The cup-shaped hollow member and the lid are held together by a hinge or fastening means, and fastening / locking means.