105 results about "Dose adjustment" patented technology

The invention relates to the technical field of medical information, and discloses a dosage regulation and control data storage method and system based on multi-modal diagnosis and treatment data, and the method comprises the steps: obtaining historical diagnosis and treatment data and historical dosage data of a patient; matching the diagnosis result data with health diagnosis result data in the health diagnosis and treatment data, and matching the wearable device data with health wearable device data in the health diagnosis and treatment data; determining whether to adjust the historical dose data to obtain the current dose, and outputting a judgment result needing to be adjusted; and obtaining the adjusted dose data, and storing the diagnosis result data, the diagnosis result similarity, the wearable device data, the wearable data similarity, the historical dose data and the adjusted dose data into a dose adjustment unit in a patient database. According to the invention, multi-modal diagnosis and treatment data can be integrated and applied to dose regulation and control, and a complete medication decision data chain is constructed.

A dose dial back mechanism of an energy storage injection pen, comprising: a support sleeve (1), which can rotate for dose setting and dose dial back, and can trigger an injection action; an energy storage sleeve (7), which is mounted outside the support sleeve (1) and is linked with the support sleeve (1) to achieve dose adjustment and execute an injection action according to the dose; a fixing gear (4), which is mounted at the front end of the energy storage sleeve (7) and can limit the rotation direction of the energy storage sleeve (7) after being engaged with the energy storage sleeve (7), such that when the fixing gear (4) is engaged with the energy storage sleeve (7), the energy storage sleeve (7) can rotate relative to the fixing gear (4) for dose setting or the energy storage sleeve (7) can drive the fixing gear (4) to rotate synchronously, and when the fixing gear (4) is disengaged from the energy storage sleeve (7), the energy storage sleeve (7) can rotate relative to the fixing gear (4) for dose dial back; and a transmission sleeve (6), which is configured to connect the support sleeve (1) and the energy storage sleeve (7) to achieve linkage, and can push away the fixing gear (4) to enable the fixing gear (4) to disengage from the energy storage sleeve (7). The dose dial back mechanism can achieve dose setting and dose dial back, and therefore can better adjust the dose.

The embodiment of the invention discloses a coprophilous fungus transplantation donor and acceptor dynamic matching method, device and equipment and a medium, and the method comprises the steps: responding to a donor and acceptor matching request, and obtaining the monitoring data of a to-be-matched acceptor after coprophilous fungus transplantation at the current preset sampling time; wherein the monitoring data after coprophilous fungus transplantation is determined on the basis of the coprophilous fungus transplantation operation of a to-be-matched receptor completed by the coprophilous fungus flora of any target donor, and the target donor is determined by performing adaptability matching on the gene feature information, the immune feature information and the clinical feature information of the to-be-matched receptor and a plurality of to-be-selected donors; and inputting monitoring data after coprophilous fungi transplantation into the transplantation strategy control model, outputting at least one of a donor switching strategy and a dose adjustment strategy for adjusting a to-be-matched receptor in a next time period, realizing comprehensive compatibility evaluation through multi-modal data integration, continuously optimizing a treatment scheme by means of a dynamic feedback mechanism, and improving the compatibility of the to-be-matched receptor. And the accuracy and adaptability of coprophilous fungus transplantation treatment are remarkably improved.

The invention relates to the technical field of medical instruments, in particular to a dose adjusting mechanism of an injection device and the injection device. A push rod part penetrates through a holding part and is in threaded connection with the holding part, a sound tooth part sleeves the push rod part and is in circumferential limiting connection with the push rod part, and the push rod part can move in the axial direction relative to the sound tooth part; one-way clamping grooves distributed in the circumferential direction are formed in the circumferential wall defining the containing cavity, the sound tooth part is located in the containing cavity, the sound tooth part is provided with an elastic clamping part, and the elastic clamping part is clamped into any one of the one-way clamping grooves; under the state that the push rod part is pressed, the push rod part can move in the axial direction and drive the sound tooth part to rotate synchronously under the action of the threads, so that the elastic clamping part slides along the peripheral wall defining the containing cavity to be clamped into one of the one-way clamping grooves in the front end. Axial control of the push rod part is converted into rotation control of the sound tooth part, rotation movement of the sound tooth part is discretized into fixed angle grading, the axial displacement of single-time grading of the push rod part is extremely small, and the small-dose injection requirement is met.

The invention discloses a dose adjustment forward and reverse rotation structure of a medicine delivery device, and belongs to the technical field of medical instruments, the dose adjustment forward and reverse rotation structure comprises a knob, a ratchet seat, ratchet teeth, jumping teeth and an injection spring, the ratchet seat is connected with the ratchet teeth through a forward sound generating part, and the ratchet teeth and the jumping teeth are connected through a reverse sound generating part in a clutch mode; a first forward rotation cooperation part and a first reverse rotation cooperation part are arranged on the rotary knob, a second forward rotation cooperation part and a second reverse rotation cooperation part are arranged on the jumping teeth, and the injection spring is used for enabling the ratchet wheel teeth to be connected with the jumping teeth. The device is simple in structure, convenient to install and good in stability, the preset dosage can be adjusted through clockwise rotation, the force stored by the torsion spring can be clamped, the preset dosage can be reduced through anticlockwise rotation until the preset dosage returns to the zero position, forward rotation is converted into radial elastic tooth jumping meshing sound production, and reverse rotation is converted into axial tooth jumping meshing sound production.

The invention discloses a brain tumor disease treatment effect evaluation method, and belongs to the technical field of radiotherapy plan evaluation, and the method specifically comprises the steps: obtaining the brain multi-modal image data of a patient, and extracting a three-dimensional tumor region and a corresponding perfusion parameter; constructing a biological target region hierarchical structure containing a tumor overall region and an anoxic subregion; a relative hypoxia degree parameter is obtained by calculating the cerebral blood flow ratio of the hypoxia subregion to other regions of the tumor; historical treatment case data are deconstructed, and a dose-curative effect associated parameter set is established; training and outputting a dose adjustment strategy model for the hypoxia subregion; and generating a final radiotherapy dose planning scheme according to a dose adjustment value output by the model in combination with a clinical guide basic dose. Through a data-driven dose decision-making mechanism, the limitation of traditional uniform dose irradiation is overcome, so that an objective and reliable evaluation basis is provided for clinical selection and optimization of personalized treatment schemes.

The invention relates to the technical field of medical instruments, in particular to a dose adjusting mechanism of an injection device and the injection device. The push rod part penetrates through the holding part and is in threaded connection; the push rod part is sleeved with the transmission tooth part and limited in the circumferential direction, and the push rod part can move in the axial direction relative to the transmission tooth part. The transmission tooth part comprises a driven ratchet; the driving rod part can be switched from an initial position to an end position, and at the initial position, the driving ratchet and the driven ratchet are spaced in the axial direction and staggered by a preset angle in the circumferential direction; at the ending position, the driving ratchet is meshed with the driven ratchet, and the transmission tooth part rotates by an angle of one driving ratchet; the reset part drives the driving rod part to return to the initial position when the pressing force is released. The rotation angle of the transmission tooth part corresponds to the axial displacement of the push rod part, rotation of the transmission tooth part is discretized through one-by-one meshing of the driving ratchets and the driven ratchets, the single displacement of the push rod part is smaller, and the small-dose injection requirement is met.

The invention relates to the technical field of gastrointestinal tumor chemotherapy risk assessment, and particularly discloses a gastrointestinal tumor chemotherapy risk scoring model and a construction method thereof, and the method comprises the steps: obtaining the individualized feature data and basic physiological data of a historical patient, and constructing an individualized difference library with a unique ID, and a core influence library; the method comprises the following steps: standardizing and coding double-library data, synchronizing clinical data containing treatment effect codes, forming a data dictionary, acquiring and coding current gastrointestinal tumor patient data, and matching the data dictionary to judge individual difference abnormity; when the first data set is abnormal, constructing a first data set, screening core independent variables through Logistic regression, and constructing a scoring model by using an LSTM (Long Short Term Memory) model; when no abnormity exists, redundant codes are removed to obtain a second data set, and modeling is conducted through the same method. Through double-library linkage and scene-divided modeling, the three-level toxicity risk prediction precision is improved, data support is provided for clinical chemotherapy dose adjustment and toxicity prevention, and the risk of excessive treatment or insufficient treatment is reduced.

This invention belongs to the field of acute lymphoblastic leukemia (ALL) technology and discloses an ALL scoring system. The system divides the entire treatment cycle into three major phases: induction remission, consolidation therapy, and maintenance therapy. Each phase is further subdivided into sub-phases, forming a two-tiered data acquisition architecture. During data collection, baseline data such as age and fusion genes are included, along with dynamic data such as the rate of MRD decline and drug exposure concentration. Simultaneously, anchor triggering mechanisms are set at different sub-phases, making the risk score more closely aligned with the patient's real-time condition and providing a more accurate reference for clinical treatment strategy selection. The feature adaptation module matches subtype-specific biomarkers and analyzes the interaction between rare subtypes and comorbidities. The matching module calls upon a three-dimensional protocol library to select standardized protocols for common subtypes, targeted protocols for rare subtypes, and dose adjustment or drug substitution protocols for patients with comorbidities, matching more suitable protocols for different patients.

The invention provides an individualized ovulation promoting scheme and gonadotropin initial dose prediction method based on multi-cycle time sequence modeling and related equipment, and is applied to the technical field of data processing. The method comprises the following steps: firstly, receiving multi-cycle clinical data and basic information of a target user for IVF / ICSI pregnancy-assisted patients, and eliminating unqualified samples to generate an initial data set; after SHAP screening features, training / test set division and SMOTE sample equalization are carried out, an initial model is constructed through a sliding window time sequence module and a multi-algorithm engine; a target model is generated through training and evaluation, and a COS scheme prediction signal and multi-period Gn dose adjustment information are generated in combination with hierarchical classification and weighted integration; calibration information is generated through clinical data verification, after target user information is subjected to standardization processing, an individualized COS scheme and a Gn initial dose are output through a target model, and multi-cycle dynamic accurate recommendation is achieved.

Most therapeutic treatments require dose adjustment after initial administration. Dosage adjustment is crucial to ensuring optimal safety and efficacy characteristics of the treatment. Gene therapy is inherently limited by the inability to adjust the dose after initial administration. This invention describes a genetic element capable of dose adjustment after the initial administration of gene therapy. The realization of dose adjustment allows for the replacement of multiple subcutaneous protein injection regimens with single-injection gene therapy, thereby improving pharmacokinetics, safety / efficacy characteristics, medication adherence, and reducing healthcare costs.

The invention discloses a medication management system with dose adjustment and a medication management method, and the method comprises the steps: enabling a doctor to give a medication scheme according to the illness state of a patient, update an individualized medication scheme according to a medication compliance report of the patient, and upload the medication scheme to a cloud server through the arrangement of a doctor terminal; and the cloud server sends a generated patient medication compliance report to a doctor end. The patient end confirms the medication scheme and generates a medication plan scheme according to the medication scheme; the intelligent medicine box controls the target medicine bin to discharge medicine according to the medicine taking scheme and the medicine taking plan scheme. Through cooperative work among the doctor end, the patient end and the intelligent medicine box, an individualized medicine taking scheme based on the doctor end is realized, and a patient can automatically execute a new medicine taking plan scheme and record medicine taking behaviors, so that dynamic dose control is realized in the medicine taking process of the patient, data interaction and medicine taking compliance feedback between the doctor and the patient are completed, and the patient can take medicine conveniently. The safety and the standardization of long-term medication of patients with chronic diseases are improved.

The invention relates to a firing device for a needleless injector and a needleless injection system. The needleless injector includes an injection chamber housing and a piston assembly. The launch device includes a support housing, a power push rod, and a dose adjustment device. The support housing is configured to be connectable to the injection chamber housing. The power push rod is configured to be connectable to the piston assembly and movable relative to the support housing. The dose adjusting device comprises a dose adjusting disc and a dose adjusting column, the dose adjusting disc is rotatably connected to the supporting shell, a plurality of dose grooves are formed in the dose adjusting disc, the depths of the dose grooves are different from one another, and the dose adjusting column is arranged on the power push rod and can move along with the power push rod. The dose adjusting column can change the movement stroke of the power push rod by being matched with different dose grooves. According to the needleless injection system of the scheme, a user can conveniently achieve injection of a preset dose.

An injection pen and a dose adjustment mechanism thereof. The dose adjustment mechanism comprises a power rod, a barrel body, a ball, a sleeve, and a torsion spring. The barrel body is sleeved outside the power rod. A spiral channel extending in an axial direction of the power rod is formed between an inner barrel wall of the barrel body and an outer rod wall of the power rod. The ball is rollably arranged in the spiral channel. The barrel body is relatively fixed to an upper pen barrel of the injection pen in a circumferential direction. The upper end of the torsion spring is relatively fixed to the upper pen barrel, and the lower end of the torsion spring is connected to the sleeve. The power rod can rotate relative to the barrel body under the action of external force. The sleeve is in circumferential limiting connection to the power rod. The sleeve is configured for being in transmission fit with a transmission mechanism of the injection pen. By means of structural optimization, the rolling smoothness of the ball in the dose adjustment mechanism can be ensured, so that the ball can be smoothly reset, thereby improving the reliability and safety during the use of the injection pen.

This application discloses a feedback-optimized injection pen, relating to the field of medical device technology. The feedback-optimized injection pen includes a pen body, an adjustment mechanism, and an injection mechanism. The pen body includes a pen body with an outer cylinder and an inner cylinder, with a feedback rib on the outer side of the inner cylinder. The adjustment mechanism includes a dose hub, the outer side of which is threaded into the outer cylinder. The dose hub has a spring arm, which contacts the feedback rib to generate feedback when the dose hub rotates. The injection mechanism and adjustment mechanism have both coupled and decoupled states. When the injection mechanism is coupled to the adjustment mechanism, the injection mechanism pushes the liquid medication from the vial container under the action of the adjustment mechanism. This feedback-optimized injection pen, through its double-cylinder design, strengthens the assembly relationship with the dose hub and generates precise adjustment feedback during dose adjustment through the contact between the spring arm and the feedback rib, thereby improving the accuracy of dose setting and the reliability of the injection pen.

An assembly and method for housing and securing exposed dose adjustment control mechanisms of medical devices used to administer various medical therapies, is provided. In an exemplary embodiment, the inventive assembly and method serve to house and secure exposed dose adjustment control mechanisms of oxygen concentrators used to provide oxygen therapy. The inventive assembly, which securely encloses a dose adjustment control mechanism, permitting access only to select individuals, is made up of a cup-shaped hollow member having a through-hole in a distal wall, and a lid. The cup-shaped hollow member and the lid are held together by a hinge or fastening means, and fastening / locking means.

The invention discloses an automatic injection pen, which relates to the technical field of injection pens and comprises a pen shell, a pen cap, an injection mechanism, a dose adjusting mechanism, an energy storage mechanism, a clutch mechanism and a push rod non-return mechanism, the pen shell comprises an upper pen shell and a lower pen shell which are connected with each other; the end of the upper pen shell is rotationally connected with a knob, and a button is clamped to the end of the knob in a limiting mode. The pen cap is sleeved on the surface of the end part of the lower pen shell; after injection is finished every time, the push rod is kept in the original position and tightly abuts against the piston in the clamping type bottle, and during next injection, only dosage adjustment is needed, emptying operation is not needed, and automatic multi-time adjustment injection is achieved; meanwhile, the dosage adjusting operation and the force applying energy storage operation are synchronously carried out, and after liquid medicine injection is completed, the injector can return to the original position, so that convenience is provided for next injection, and the whole injection operation is simpler and more convenient.

This invention relates to the field of clinical medical and nursing device technology, specifically to an auxiliary turntable for blood glucose management and insulin dose adjustment in critically ill patients. It includes a base and a recommendation component. A support column is fixedly connected to the top of the base. The recommendation component includes a recommendation disc fitted outside the support column. A judgment component, including a judgment disc fitted outside the support column, is fitted outside the support column and is located on top of the recommendation cover. An identification component, including an identification disc fitted outside the support column, is fitted outside the support column. A base component, including a base disc fitted outside the support column, is located on top of the identification cover. Through the base, support column, and four sets of adjustment components, standardized and visual matching of multiple blood glucose indicators and insulin adjustment recommendations is achieved. Combined with three-color risk label strips, it quickly identifies abnormal blood glucose levels and fluctuation risks, enabling early detection and intervention, and reducing dose adjustment errors due to experience.

The invention relates to the field of medical health and intelligent optimization, and discloses a dialysis anticoagulation risk intelligent early warning method and system fused with multi-modal physiological signals, and the method comprises the steps: S1, synchronously collecting the multi-modal data of a patient in the dialysis process, and standardizing the multi-modal data into a unified time sequence matrix; s2, inputting the unified time sequence matrix into an anticoagulation risk prediction model, performing first-class feature extraction on continuous monitoring signals, performing second-class feature extraction on discrete detection signals, and extracting embedding features of patient individualization and treatment scene data; performing cross-modal fusion on the three types of extracted features to generate a fusion feature vector, and outputting a thrombus risk probability and a bleeding risk probability in a future preset time period; s3, when the risk probability exceeds the corresponding early warning threshold value, performing search optimization on the administration parameter of the current anticoagulant, and generating a dose adjustment instruction; and S4, executing the adjustment instruction, predicting the anti-coagulation risk again, and evaluating the regulation and control effect. Therefore, the safety and effectiveness of the hemodialysis process are remarkably improved.

The present disclosure provides an X-ray dose adjustment method, apparatus, medical imaging system, medium, and product. The X-ray dose adjustment method for a medical imaging system includes: obtaining a set first frame rate; sending at least an instruction to perform dose adjustment based on a second frame rate, wherein the second frame rate is greater than the first frame rate and less than or equal to the maximum allowable frame rate of the medical imaging system; determining whether the dose adjustment has reached a stable state; and in response to determining that the dose adjustment has reached a stable state, sending at least an instruction to switch the medical imaging system to the first frame rate. Using the method according to an embodiment of the present disclosure, dose adjustment can be performed based on a higher frame rate, shortening the dose adjustment time and improving imaging quality.

The application is suitable for the field of artificial intelligence and medical health technology, and provides a medicine mutual exclusion identification and dose adjustment method and device and a storage medium, which comprises the following steps: obtaining a first prescription and a second prescription corresponding to a target disease; wherein the first prescription and the second prescription are obtained based on different medical systems; the first prescription comprises at least one first medicine and a first dose corresponding to the first medicine; the second prescription comprises at least one second medicine and a second dose corresponding to the second medicine; identifying medicine mutual exclusion according to the first prescription and the second prescription to obtain a first identification result; and adjusting the first dose according to the first identification result to obtain an adjusted first prescription. The above method provides a safer and more suitable medication scheme for cross-medical system joint diagnosis and treatment.

The invention discloses a cardiovascular drug dose regulation and control system based on reinforcement learning, and relates to the technical field of medical artificial intelligence, and the system comprises a data acquisition module which collects physiological data, metabolic parameters, a drug interaction matrix and a current drug combination of a patient in real time; the adjustment factor calculation module calculates a drug metabolism rate adjustment factor through a pharmacokinetic model; the interaction modulation module adjusts the interaction intensity according to the adjustment factor; the risk score calculation module calculates the adverse reaction risk of the patient based on the adjusted interaction matrix, the drug combination and the physiological data; the first processing module judges whether the risk score exceeds the standard or not, and if yes, the risk is reduced through medicine replacement or dosage reduction; if the risk score is lower than a second threshold value, the second processing module maintains the current dose, otherwise, a dose adjustment strategy is optimized based on reinforcement learning; according to the method, the medicine dosage adjustment can be more fit with the actual metabolic characteristics of the patient, and the accuracy and individualization degree of treatment are improved.

The present invention relates to an injection mechanism and syringe with an injection dose adjustment function. The injection mechanism (1) has a housing (10) which contains a plunger (80) and an injection dose adjustment means (1a) and a retraction control means (1b) connected to the plunger (80). The injection dose adjustment means (1a) drives the plunger (80) by rotating a tubular member (20) with a dose adjustment knob (30) to drive a drive ring (50), thereby generating elastic potential energy in an elastic means (40).

The present invention discloses a precision automatic injection device with adjustable injection dose, comprising an upper pen body shell and a dose adjustment assembly, the dose adjustment assembly including an adjustment knob, a graduated cylinder, and an energy storage component. The adjustment knob is rotatably mounted on the upper end of the upper pen body shell, an intermittent thread is provided on the inner circumference of the upper pen body shell, and a spiral groove is provided on the outer circumference of the graduated cylinder. The adjustment knob is transmission-connected to the energy storage component disposed within the graduated cylinder. Rotating the adjustment knob adjusts the energy stored in the energy storage component for injection through the graduations of the graduated cylinder displayed in a window. The precision automatic injection device with adjustable injection dose according to the present invention comprises an upper pen body shell with a graduated cylinder linked to the energy storage component, a window is provided on the upper pen body shell, and rotating the adjustment knob adjusts the energy stored in the energy storage component for injection through the graduations of the graduated cylinder displayed in the window. The device can accurately adjust the injection dose and set different injection doses according to different needs.

The present application relates to the field of medical device technology, and specifically to a dose adjustment mechanism and injection device for an injection device, wherein a push rod portion passes through a grip portion and is circumferentially limited. The push rod portion is axially movable relative to the grip portion. A snap tooth portion is fitted over the push rod portion and threadedly connected. The grip portion has a receiving cavity, and the circumferential wall surrounding the receiving cavity is provided with circumferentially distributed one-way slots. The snap tooth portion is located in the receiving cavity and has an elastic snap portion that snaps into any one-way slot. When the push rod portion is subjected to a pressing force, the push rod portion can move axially, the snap tooth portion can rotate under the action of the thread, and the elastic snap portion slides along the circumferential wall surrounding the receiving cavity to snap into one of the one-way slots at the front end. The present application converts axial displacement control into rotational motion control, discretizing the rotational motion of the snap tooth portion into fixed-angle steps. The axial displacement of the push rod portion in a single step is extremely small, meeting the needs of small-dose injections.

The invention discloses an accurate dose control method and system for brucellosis traditional Chinese and western medicine combined medication, and relates to the technical field of medical treatment. According to the method, individualized data of a patient is obtained through a multi-modal data acquisition technology, a population pharmacokinetic-pharmacodynamic model is constructed by using the data, the population pharmacokinetic-pharmacodynamic model comprises a western medicine module, a traditional Chinese medicine module and a coupling interface, and pharmacokinetic modeling of traditional Chinese medicine and western medicine combined medication is achieved. By monitoring the physiological indexes and symptom data of a patient in real time and combining a traditional Chinese medicine syndrome dynamic scoring algorithm and a reinforcement learning dynamic dose adjustment algorithm, the real-time accurate adjustment of the drug dose is realized. In addition, the method further comprises a traditional Chinese and western medicine synergistic effect optimization step, a synergistic index is calculated based on the knowledge graph and the graph attention network, and a dosage optimization rule is formulated, and the implementation of the method is beneficial for improving the treatment effect of brucellosis and reducing side effects.

The invention discloses a pen type insulin syringe with digital display and data transmission functions. The pen type insulin syringe comprises a shell assembly, a refill sleeve, a shell lock, a dose adjusting knob, a hollow penetrating contact type rotary encoder, an injection driving mechanism, a dose memory display module, an injection dose indication window and an NFC data transmission system. When the device works, the dose adjusting knob is pulled out in the axial direction of the shell assembly, locking of the clamping structure on the dose adjusting knob is relieved, the dose adjusting knob is made to rotate freely, then the hollow penetrating contact type rotary encoder is driven by the dose adjusting knob to conduct dose adjustment, and after dose parameter setting is completed, the injection button is pressed in the axial direction, so that the dose parameter setting is completed. The injection driving mechanism is triggered to move along a preset track so as to push the medicament to complete the injection process. High-precision digital control and intelligent data management in the insulin infusion process are achieved, the accuracy of dose adjustment and injection is remarkably improved, and the convenience of user operation experience and medication compliance management is also optimized.

The dose adjusting and feedback mechanism of the injection pen comprises a screw sleeve and a metering dial support, when the screw sleeve rotates reversely, a protrusion directly acts on a pawl lifting face, a pawl is forcibly lifted to be partially separated from ratchets, and stepping locking is relieved; compared with traditional tooth-by-tooth callback, the difficulty degree is greatly reduced, the reset operation efficiency is improved, operation delay in emergency is avoided, reset is achieved only through mechanical interference of the protrusions and the pawls, and 80% of quick-wear parts are reduced.

Disclosed is a disposable multi-dose high-precision insulin injection apparatus, comprising a housing, and a dose adjustment unit and an injection transmission unit that are arranged in the housing. The dose adjustment unit is arranged in the upper part in the housing, and the injection transmission unit is arranged in the lower part in the housing. A dose setting unit is in transmission connection with the injection transmission unit. The dose adjustment unit is used for presetting an injection dose, and the injection transmission unit is used for transmitting injection power and discharging the preset injection dose to complete an injection. The disposable multi-dose high-precision insulin injection apparatus described in the present invention uses the dose setting unit to set a dose of insulin to be injected and uses the injection transmission unit to complete the injection of the corresponding dose. The dose setting unit can accurately set a dose to be injected. The apparatus is simple and convenient to operate and cost-effective.

Embodiments of the present disclosure relate to dose adjustment for maximum field delivery time in radiation therapy treatment planning. A proton therapy system may include at least one processor and a memory storing computer executable instructions. The at least one processor is configured to execute the computer executable instructions to cause the proton therapy system to selectively adjust a treatment plan for a proton therapy treatment of a target volume based on a treatment delivery time of the treatment plan and a threshold maximum treatment delivery time, the treatment plan specifies at least proton therapy field characteristics for treating the target volume.