The invention provides a making method and apparatus of three-dimensional comics. The method mainly comprises following steps: receiving and storing a comics script and a plan; designing a role draftaccording to the comics script; performing three-dimensional role modeling, UV extension, UV sticker drawing, three-dimensional role model skeleton binding, three-dimensional role model skinning, three-dimensional scene modeling and three-dimensional prop modeling according to the role design draft, and obtaining three-dimensional role, scene, and prop models through sticker, binding and skinning;performing comics storyboard designing and drawing on the comics script, the plan, and the three-dimensional role, scene and prop models to obtain a comics storyboard draft; performing movement modeling matching according to the storyboard by employing the three-dimensional role model, and producing a three-dimensional comics manuscript through rendering; making a comics sketch according to the three-dimensional comics manuscript; and performing outline drawing and coloring on the three-dimensional comics manuscript, and adding lines, onomatopoetic words and effect lines. According to the method and apparatus, the three-dimensional comics with large amount and excellent quality can be obtained.