The invention relates to a manufacturing method of nitroxyl-based water-soluble polyamide resin artificial leather, which is to use nitroxyl-based water-soluble polyamide resin to prepare coating slurry, then apply the coating slurry to the surface of artificial leather base cloth, and then undergo dyeing treatment to obtain The dyed polyamide artificial leather and the finishing paste include the following components in parts by mass: 100 parts of nitroxyl water-soluble polyamide resin, 20-120 parts of dimethylformamide, and 20-120 parts of acetone. Nitroxyl water-soluble polyamide resin is used as artificial leather surface coating material, which can be dyed with dyes. After dyeing, the color effect of dyeing can be obtained, so that the product has bright colors, good coating permeability, and surface color fastness. High, small color migration characteristics.