The invention discloses a human factor reliability analysis method for an operator of a digital master control room of a nuclear power station. The invention discloses a human factor reliability analysis method, which relates to the technical field of human factor engineering, and comprises the following steps of: step 1, determining that the dynamic cognitive process of an operator of a digital master control room of a nuclear power station under an accident comprises three cognitive stages of monitoring, decision making and execution, and representing the human factor reliability by the sumof the error rates of the three cognitive stages; step 2, defining an error rate relational expression of each cognitive stage by adopting an exponential structure; step 3, determining influence factors of each cognitive stage in the step 2 and weights of the influence factors at different grades; and step 4, determining a correction coefficient of each cognitive stage in the step 2. According tothe human factor reliability analysis method for the operator of the digital master control room of the nuclear power plant, the digital master control room of the nuclear power plant is taken as thebackground, the human factor reliability analysis method for the operator based on the PSFs weight is provided, the human factor reliability of the accident execution process of the operator can be improved, and errors are reduced.