54 results about "Hematology analyzers" patented technology

The invention discloses a sample detection device applied to instant detection, a bearing assembly of the sample detection device comprises a first loading seat and a second loading seat, the first loading seat is used for bearing a kit and a to-be-detected sample, or the first loading seat is used for bearing the kit, and the to-be-detected sample is stored in the kit; the second loading seat is used for bearing a reagent card, and the reagent card is provided with a sample adding area. The pipetting assembly is used for acquiring the to-be-detected sample on the first loading seat and transferring the to-be-detected sample to the reagent card for sample adding, so that automatic sample adding of the reagent card is realized, the operation is simple, manual intervention can be effectively reduced, and the detection efficiency of the hematology analyzer is improved.

The invention discloses a hematology analyzer and a detection method for hole blockage of a flow chamber, in the hematology analyzer provided by the invention, in the process that sample liquid enters the flow chamber for sample detection, a control unit can also obtain signal parameters based on optical signals of the sample liquid flowing through the flow chamber; whether the flow chamber is blocked or not is judged, the safety of the flow chamber is improved, and the detection efficiency of an optical detection system on sample liquid is improved. Meanwhile, in the process of detecting the sample liquid, whether the flow chamber has the hole blocking problem or not can be judged, the step of judging the hole blocking of the flow chamber does not need to be additionally set, the operation efficiency of the hematology analyzer is improved, and the use experience of a user on the hematology analyzer is improved.

The utility model provides a deviation correcting device for needle assembly and blood analyzer assembly equipment. The deviation correcting device for needle assembling comprises a feeding mechanism, a clamping mechanism and a rotary assembling mechanism, the rotary assembling mechanism comprises a first support, a rotating assembly, a sleeve, a first double-shaft driving part and two guide rods, the rotating assembly is installed on the first support, the sleeve is connected to the power output end of the rotating assembly, and the first double-shaft driving part is installed on the first support. The first double-shaft driving part is installed on the rotating assembly, the two guide rods are connected with the power output end of the first double-shaft driving part respectively, each guide rod is provided with a guide unit, the two guide units jointly form a guide hole, the guide hole and a feeding port of the sleeve are oppositely arranged, and the two guide units are arranged in the guide hole. The rotating assembly is used for driving the sleeve and the two guide rods to move, so that the liquid inlet end of the needle penetrates through the guide hole and then enters the sleeve.

A hematology analyzer for analyzing a fluid sample and comprising a frame body defining a first axis (X-X′) and a second axis (Y-Y′), a cartridge unit having a first compartment containing the fluid sample and a second compartment containing a cleaning fluid, a fluid analysis module comprising a first probe and a second probe, a first transmission unit configured to hold and move the cartridge unit along the first axis (X-X′) to align the first compartment and the second compartment with the first probe and the second probe, respectively, and a second transmission unit configured to move the fluid analysis module along the second axis (Y-Y′) such that the first probe and the second probe pierce the first compartment and the second compartment, respectively.

The invention discloses a POCT (Point of Care Testing) hematology analyzer. In the application, the first bearing position is arranged on the sample injection module to bear the detection card for receiving the first to-be-detected sample, and the second bearing position is arranged on the first detection module to bear the detection card after receiving the first to-be-detected sample, so that the receiving and detection of the first to-be-detected sample are separately carried out at different bearing positions of different modules; the transfer module is arranged at the output end of the driving module of the preprocessing module, so that the driving module can drive the transfer module to transfer the detection card from the first bearing position to the second bearing position after driving the pipetting consumable through the loading module to transfer the first to-be-detected sample into the detection card at the first bearing position; therefore, the driving module is ingeniously used for driving the transfer module, and a driving device special for driving the transfer module is avoided, so that the overall structure of the analyzer is simpler, the production cost is reduced, and the analyzer is more compact and miniaturized in structure.

The utility model discloses a built-in hemolytic agent bottle and hematology analyzer relates to medical instrument technical field, wherein the built-in hemolytic agent bottle includes solvent bottle, movable joint block and pipeline subassembly, solvent bottle includes mutually communicated bottle body and bottle cap, bottle body and bottle cap detachable connection, bottle cap far away from bottle body side is equipped with the movable mouth; the movable connector block is movably arranged at the movable opening, the movable connector block and the movable opening are arranged in a clearance mode, and the movable connector block is provided with a mounting hole which is formed in the thickness direction in a penetrating mode; the pipeline assembly is fixedly arranged at the mounting hole, one end of the pipeline assembly extends into the bottle body, and the other end of the pipeline assembly penetrates out of the mounting hole and is communicated with an external liquid system. According to the technical scheme, the problem that when a bottle cap of an existing built-in hemolytic agent bottle is screwed down, a pipeline is prone to being bent is solved.

The invention discloses a reagent conveying device and a blood analyzer. The reagent conveying device comprises a reagent assembly, a first pipeline, a constant delivery pump assembly, a second pipeline and a controller. The second pipeline is connected to the joint of the first sub-pipeline and the second sub-pipeline of the first pipeline, and the second sub-pipeline is connected with the liquid using assembly through the metering pump assembly. The controller controls the constant delivery pump assembly to be started, so that the reagent in the reagent assembly is conveyed into the liquid using assembly through the first pipeline. When the bubbles detected on the first sub-pipeline are responded, the controller judges that the reagent of the reagent assembly is insufficient, controls the constant delivery pump assembly to be closed, and conveys the bubbles of the first sub-pipeline into the second pipeline, so that the bubbles are prevented from entering the constant delivery pump assembly through the second sub-pipeline, and the safety of the constant delivery pump assembly is improved; the time for discharging bubbles of the reagent conveying device is shortened, and the reagent conveying efficiency and the detection accuracy of the reagent conveying device are improved.

A computer-implemented method for determining states in vivo and in vitro by analyzing blood parameters, including obtaining blood parameters of a blood sample by a hematology analyzer, the blood parameters including quantitative and qualitative measurement variables, and the measurement variables include properties of individual cells, and the individual cells comprise blood cells. The computer-implemented method further includes creating a scatterplot having at least two axes, and each axis of the scatterplot comprises a different measurement variable; and determining an in-vivo and / or in-vitro and / or post-mortem state by a deep learning model and / or a machine learning model. The input variable for the deep learning model includes a scatterplot, and the input variable for the machine learning model includes 1D vector. The 1D vector is created by vectorizing the scatterplot; and automatically generating a report including the result regarding the determination of the state.

1. The name of the product under this design: Fully Automatic Hematology Analyzer (New 8 Series). 2. Purpose of the product of this design: for use in medical and health care, for processing blood samples, analyzing formed elements in human blood, and providing relevant information. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The present invention provides a method of identifying and mitigating a risk of deathloss of an animal, comprising receiving, at a processor from a hematology analyzer, information obtained from a sample from said animal, wherein said information comprises a leukocyte absolute count and a leukocyte differential from said sample, said sample comprising leukocytes, analyzing, by said processor, said leukocyte absolute count and said leukocyte differential to determine a survivability index for said animal, and managing the animal based on the survivability index.

Disclosed in the present application is a POCT hematology analyzer. The POCT hematology analyzer comprises: a cell counting assembly movable relative to a reagent kit, wherein the cell counting assembly comprises a main body provided with a front chamber and a rear chamber; a microporous sheet configured to isolate the front chamber from the rear chamber and provided with a micropore, the front chamber being in communication with the rear chamber by means of the micropore; and a first electrode, which penetrates and is arranged in the rear chamber and configured to be electrically connected to a test sample in the rear chamber, wherein the range of the shortest distance between the portion of the first electrode that penetrates and is arranged in the rear chamber and the micropore is 2-20 mm. By the above means, it is possible to prevent the first electrode from being too far away from or too close to the micropore, thereby reducing interference from other cells, minimizing bubble formation, and accordingly improving the accuracy of test results of the POCT hematology analyzer.

The disclosure features calibration fluids that include a plurality of beads, such as cellulose, silica, poly(methyl-methacrylate) (PMMA), melamine, cross-linked agarose, polyvinylacetate (PVA), and / or polystyrene beads, where the beads are sized and colored to represent at least one type of blood cell; and a carrier fluid, that can include a polymer or polymerizing matrix, e.g., a water-soluble resin, e.g., an acrylic or polyurethane water-soluble resin or a starch or a cellulose, serum, and / or one or more or sugars. The disclosure also features methods of using the calibration fluids to calibrate automated sample preparation systems, such as automated hematology analyzer systems, e.g., image-based hematology analyzer systems.

This invention describes a method for preparation of stable hematology reference materials by producing synthetic hydrogel blood cell surrogates, which mimic human blood components in size, morphology, performance and functionality when analyzed using an automated hematology analyzer employing multiple detection technologies. Different hydrogel particles can be combined and mixed to prepare multi-parameter and multi-level hematology reference materials, which could be used for calibration, linearity verification, proficiency evaluation, and routine performance monitoring of modern automated hematology analyzers. These hydrogel particles can also be combined with processed and stabilized human blood components to prepare the reference materials of this invention.

This invention relates to the field of hematology analysis technology, and in particular to a diluent for hematology analysis, its preparation method, and its uses. The diluent comprises the following components: 0.5-15 g / L of inorganic salt, 0.01-5.0 g / L of preservative, and 0.1-0.5 g / L of stabilizing agent; the solvent of the diluent is water; the diluent also includes an anti-precipitant, selected from one or more of salt-based and organic anti-precipitants; the salt-based anti-precipitant includes one or more of thiocyanate and nitrate, with a content of 2.0-5.0 mmol / L; the organic anti-precipitant includes one or more of trehalose, mannitol, and amino acid ionic liquids, with a content of 4.0-8.0 mmol / L. In this diluent, the components work synergistically to reduce the maintenance cost of the hematology analyzer, increase its service life, and improve detection efficiency.

The application discloses a POCT hematology analyzer and a hematology analysis method, the POCT hematology analyzer performs pressure detection on a detection cell through a pressure buildup mechanism in the detection process of a kit, and a processor judges whether the airtightness of the detection cell is abnormal according to the pressure detection result of the pressure buildup mechanism; the kit can be treated in time when the air tightness of the detection cell is abnormal, so that the damage of the kit to the POCT hematology analyzer due to the problems of air leakage or hole blockage and the like is reduced, and the detection accuracy and reliability of the POCT hematology analyzer are improved.

The invention discloses a POCT (Point of Care Testing) hematology analyzer. In the application, a first bearing position is arranged on a sample introduction module and used for bearing a detection card, a second bearing position is arranged on a first detection module and used for bearing the detection card, and a first sample to be detected is transferred into the detection card located at the first bearing position through a pretreatment module; and transferring the detection card receiving the first to-be-detected sample at the first bearing position to the second bearing position through a transfer module, and detecting the settled first to-be-detected sample in the detection card at the second bearing position through the microscope unit, therefore, each detection card receives the first to-be-detected sample and the detection of the first to-be-detected sample after settlement is carried out at different bearing positions, so that the detection efficiency of the POCT hematology analyzer can be effectively improved.

The invention relates to the technical field of hematology analyzers, and discloses a cell analyzer sample introduction device which comprises a machine body, a detection cavity, a feeding drawer, a hydraulic cylinder and a sample introduction calibration module, and a bin door is hinged to the front face of the machine body. The stable and controllable driving force is provided through the electric push rod and transmitted to the single rack through the push block, the synchronous gear is matched to synchronously and symmetrically transmit the movement to the rack on the other side, clear guide is provided for placement, stable circumferential constraint is formed after clamping, and the clamping precision is improved. The test tubes are effectively prevented from deviating or shaking in the horizontal direction possibly in the subsequent conveying process, the problem that due to manual placement errors or mechanical conveying gaps, the positions of the test tubes on the horizontal plane are uncertain is solved, and therefore radial dislocation of the test tubes and puncture needles at the final detection station is avoided; the problems that the puncture needle cannot accurately pierce into the preset position of the test tube, sampling fails and even the precise puncture needle is damaged are solved.

This utility model relates to medical diagnostic equipment and in vitro laboratory diagnostics, including microfluidic impedance cytometers for rapid assessment of the white blood cell (WBC) count in whole blood. It can be used in automated systems for calculating biological age based on telomere indices (T / S) and / or associated biomarkers. The technical result is the elimination of biological age (BA) bias arising from interindividual differences in the white blood cell count (proportion of granulocytes and lymphocytes), without the use of a separate blood analyzer, thanks to integrated multi-frequency impedance classification of WBC and automatic transfer of the calculated proportions to the telomere computing circuit (TEL-BA / BA-Dock) for T / S → BA regression correction.The technical result is achieved in that the impedance microcytometer "WBC-Adjust" is made in the form of an embedded (inline) micromodule installed downstream of the qPCR cartridge, and contains a microfluidic channel with a hydrodynamic focusing system, an array of measuring electrodes connected to a multi-frequency impedance meter, an electronic unit for classifying cells according to a set of "size-multi-frequency dielectric profile" features, a communication interface (wired / wireless) for transmitting calculated WBC shares to the TEL-BA / BA-Dock, as well as a controller implementing self-testing protocols, temperature monitoring and synchronization with the main measuring cycle of the telomeric cartridge.

The present invention discloses a multi-channel micro-quantification system for a blood cell analyzer, which includes a front cover of a ceramic blood distribution valve, a ceramic shunt plate, a rear cover of the ceramic blood distribution valve, a rotary valve plate mechanism, and a five-channel micro-quantification blood distribution valve. The front cover of the ceramic blood distribution valve is rotatably connected to the ceramic shunt plate. The rear cover of the ceramic blood distribution valve is rotatably connected to the ceramic shunt plate and is located on the side away from the front cover of the ceramic blood distribution valve. The rotary valve plate mechanism is fixedly connected to the front cover of the ceramic blood distribution valve. The five-channel micro-quantification blood distribution valve is fixedly connected to the front cover of the ceramic blood distribution valve, the ceramic shunt plate, and the rear cover of the ceramic blood distribution valve, and penetrates through the front cover of the ceramic blood distribution valve, the ceramic shunt plate, and the rear cover of the ceramic blood distribution valve. Among them, the five-channel micro-quantification blood distribution valve includes 5 different channels, which are arranged in a circular array form, increasing the types of detections and shortening the detection time.

The utility model discloses a hematology analyzer which comprises a frame body, a power supply assembly, a control circuit board, a reagent supply assembly, an automatic sample injection assembly and a blood routine examination assembly, a first open cavity, a middle wiring cavity and a second open cavity are sequentially formed in the middle of the frame body; the power supply assembly is arranged on the rear end face of the frame body, the control circuit board is arranged at the top of the frame body, the reagent supply assembly is arranged in the second open cavity and on the front end face of the frame body, the automatic sample injection assembly is arranged on the front end face of the frame body, and the blood routine examination assembly is arranged in the first open cavity; the control circuit board is electrically connected with the power supply assembly, the reagent supply assembly, the automatic sample injection assembly and the blood routine examination assembly; the reagent supply assembly is connected with the blood routine examination assembly. According to the utility model, modularized components are adopted, and the components are reasonably arranged, so that the production and assembly efficiency can be improved, and the maintenance is easy.

1. Name of the Design Product: Kit. 2. Use of the Design Product: For loading reagents for a hematology analyzer. 3. Design Key Points of the Design Product: The product shapes of Design 1 and Design 2, the product shape of Design 3 and the arrangement of internal chambers. 4. Picture or Photograph Best Showing the Design Key Points: Perspective View 1 of Design 3. 5. Design 3 is designated as the basic design.

1. Name of the Design Product: High-throughput Hematology Analyzer. 2. Use of the Design Product: For analyzing blood cells. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photograph that Best Illustrates the Design Key Points: Stereogram.

The present invention is applicable to the field of medical equipment and discloses a blood cell analyzer, which includes a sampling component, an optical channel reaction pool, an optical detection unit, a hemoglobin detection unit, an impedance counting detection sample preparation unit, an impedance counting detection unit, a first reagent providing device, a second reagent providing device, a diluent providing device, a conveying pipeline assembly and a fluid power device. The sampling component, the optical detection unit, the optical channel reaction pool, the hemoglobin detection unit, the impedance counting detection sample preparation unit, the impedance counting detection unit, the first reagent providing device, the second reagent providing device, the diluent providing device and the fluid power device are connected through the conveying pipeline assembly to form a liquid circuit system. During a detection cycle of completing hemoglobin detection, impedance counting detection and optical detection, the average gas consumption of the liquid circuit system is less than or equal to 2.0 L / min, thereby achieving miniaturization and low-cost design of the instrument.

The invention discloses a blood sample diluting and uniformly mixing device for a hematology analyzer and the hematology analyzer. Comprising a double-round-head partition table, rotary tables rotationally installed on the two sides of the top end of the double-round-head partition table, and a plurality of L-shaped horizontal shaft brackets annularly fixed to the edges of the top ends of the rotary tables at equal intervals. The linear reciprocating type connecting rod gear oscillation assembly is installed on the outer wall of one side of the L-shaped horizontal shaft frame, the multi-hole seat is installed at the movable end of the linear reciprocating type connecting rod gear oscillation assembly, and a rotation driving assembly used for driving the two rotary tables to rotate synchronously is installed at the bottom end of the double-round-head partition table. The rotary driving assembly drives the rotary table to rotate, so that the porous seat and a plurality of blood sample test tubes in the porous seat revolve around the central axis of the rotary table, and in the process, the double-gear driven driving structure and the linear reciprocating type connecting rod gear oscillation assembly force the porous seat and the blood sample test tubes to oscillate linearly; and the simulation action that the blood sample test tube revolves and oscillates simultaneously is realized.

The invention discloses an integrated three-dimensional sheath flow channel integrated learning hematology analyzer and method, and belongs to the technical field of single cell detection.The integrated three-dimensional sheath flow channel integrated learning hematology analyzer comprises a blood sample preprocessing module, a signal detection module, a data processing module and a leukocyte classification counting result display module.The integrated three-dimensional sheath flow channel manufactured by the method is high in precision and good in depth-to-width ratio; the conductive sample liquid is surrounded by the insulating sheath liquid, so that leakage current can be effectively reduced, and an electrical signal generated when cells pass through a focusing area is enhanced; an equivalent model is used for extracting inherent electrical structure features of the cells, a neural network is used for extracting hidden features, and the precision, generalization and interpretability of a cell classification algorithm can be effectively balanced through combination of the two features; normal leukocytes can be detected, abnormal leukocytes can be classified and counted, more information and insights can be provided for clinic, and diagnosis of blood diseases is helped.

The invention relates to the technical field of blood detection and analysis, in particular to a blood analyzer reaction cup blocking and emptying detection device and method.The blood analyzer reaction cup blocking and emptying detection device comprises a reaction cup, a pressure sensor, a two-way electromagnetic valve, a first isolation tank, a second isolation tank and a pump body; small negative pressure is produced in the first isolation tank and the second isolation tank, the two-way electromagnetic valve is opened, the pump body is closed after the two-way electromagnetic valve is opened for a period of time, the two-way electromagnetic valve is closed after waiting for a period of time, the negative pressure in the second isolation tank can extract liquid in the reaction cup, and if the liquid is completely pumped, the isolation cup is in direct contact with the atmosphere. The pressure sensor detects the pressure in the first isolation tank, and if the detected pressure is smaller than a pressure threshold value, the reaction cup is slightly blocked or blocked. If the detection pressure is larger than the pressure threshold value, it is considered that instrument emptying is normal, sample separation testing can be continued, cup emptying detection is conducted again after testing is finished, and it is ensured that the instrument is normal.

The utility model provides a kind of blood cell analyzer, including sampling component, processing component, detection component and analysis component, sampling component includes sampling needle, sampling driving part, first pipeline, second pipeline, third pipeline, first switching structure, liquid discharge driving part and atmospheric communication part, wherein, the both ends of first pipeline are connected with sampling needle and first switching structure respectively, the both ends of second pipeline are connected with first switching structure and sampling driving part respectively, the both ends of third pipeline are connected with first switching structure and liquid discharge driving part respectively, atmospheric communication part can communicate third pipeline and atmosphere, first switching structure has first working state and second working state, so that sampling needle is inserted into closed test tube, closed test tube can be communicated with atmosphere by sampling needle, first pipeline and third pipeline and pressure relief when inserting sampling needle into closed test tube.The technical scheme of the application can effectively solve the problem of high cost and difficult to clean of the sampling needle in related technology.

The utility model relates to the technical field of cell analysis, and provides a sampling device of a hematology analyzer, which comprises an analyzer body, a probe is arranged at the top end of the analyzer body, a bottom plate is arranged at the bottom end of the analyzer body, and positioning blocks are fixedly connected to two sides of the upper surface of the bottom plate. The sides, close to each other, of the two positioning blocks are rotationally connected with the same two-way lead screw, one sides of the positioning blocks are fixedly connected with servo motors, the servo motors penetrate through the positioning blocks and are fixedly connected with one ends of the two-way lead screws, and the arc surface of each two-way lead screw is in threaded connection with two moving blocks. And the inner walls of the two moving blocks are rotationally connected with driving rods. The sampling device of the hematology analyzer solves the technical problem that the overall practicability and the application range of the equipment are influenced as part of catheters cannot be stably fixed and detected due to the lack of the function of adjusting the length of the catheters in the conventional equipment.

The invention discloses a POCT hematology analyzer. The POCT hematology analyzer comprises a shell; the loading seat is used for receiving the loading of the kit; the blood cell counting mechanism is arranged in the shell and can move relative to the kit; the blood cell counting mechanism includes: a body; the liquid suction part is matched with the main body to form a liquid suction channel for conveying liquid; the liquid discharging part is matched with the main body to form a liquid discharging channel for discharging liquid of the main body; and when the liquid suction channel is blocked, the blood cell counting mechanism is arranged to impact the liquid suction channel through gas in the main body, or suck liquid through the liquid discharge piece and impact the liquid suction channel through the liquid. According to the mode, the liquid suction channel is impacted by gas or liquid, so that the accuracy of a detection result of the POCT blood cell analyzer is improved; the microporous sheet of the blood cell counting mechanism does not need to be frequently replaced, the use time of the microporous sheet is delayed, and the cost is reduced.