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164 results about "Hemolytic Agents" patented technology
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Substances that are toxic to blood in general, including the clotting mechanism; hematotoxins may refer to the hematopoietic system.
Reagent test strip for analyte determination having a hemolyzing agent
InactiveUS6998248B2Bioreactor/fermenter combinationsAnalysis using chemical indicatorsReagent stripAnalyte
Reagent test strips and methods for their use in the determination of the concentration of an analyte, e.g. glucose, in a physiological sample, are provided. The subject reagent test strips include one or more members of an analyte oxidation signal producing system and at least one hemolyzing agent. The subject reagent test strips and methods are particularly suited for use in the detection of blood glucose concentrations. Also provided are kits that include the subject test strips for use in practicing the subject methods.
Owner:LIFESCAN IP HLDG LLC
Articles comprising oxidizing and hemolytic agents
The present invention relates to articles coming into contact with bodily fluids, preferably absorbent articles like sanitary napkins and pantiliners, which comprise an oxidising agent having a reduction potential higher than that of the reaction of Fe<2+> to Fe<3+> togather with a hemolytic agent. In a preferred embodiment the articles further comprise an additional odour control agent.
Owner:THE PROCTER & GAMBLE COMPANY
Method of classifying counting leucocytes
ActiveUS20050202400A1Low costAccurate classificationMicrobiological testing/measurementChemiluminescene/bioluminescenceStainingRed blood cell
There is provided a method for classifying and counting leukocytes with abnormal DNA amount, which comprises: (1) a step of staining cells in a sample obtained from a hematological sample by treatment with a hemolytic agent to lyse erythrocytes, with a fluorescent dye which can make a difference in the fluorescence intensity at least among mature leukocytes, leukocytes with abnormal DNA amount and immature leukocytes; (2) a step of introducing the sample containing the stained cells into a flow cytometer to measure scattered light and fluorescence of the respective cells; (3) a step of classifying leukocytes and coincidence cells / platelet clumps utilizing a difference in the intensity of a scattered light peak and a difference in the scattered light width; (4) a step of classifying and counting mature leukocytes, leukocytes with abnormal DNA amount and immature leukocytes, utilizing a difference in the scattered light intensity and a difference in the fluorescence intensity of leukocytes classified in the step (3).
Owner:SYSMEX CORP
Whole-blood immunoassay device and blood analyzer with same
ActiveCN103336130AFast implementation of joint inspectionSimplify the cumbersome inspection processColor/spectral properties measurementsBiological testingAbsorbanceControl unit
The invention provides a device and a method for simultaneously carrying out immune measurement and blood cell measurement on whole blood. The device comprises a reaction tank, a hemolytic reagent supplying part, a sample injection part, an immune reagent supplying part, a light irradiation unit, a control unit, a transmission light detection unit, a scattered light detection unit and an analytical calculation unit, wherein the reaction tank is used for reaction and measurement of a hemolytic agent, an immune reagent and a whole blood test sample; the hemolytic reagent supplying part is used for injecting the hemolytic agent into the reaction tank; the sample injection part is used for injecting the whole blood test sample into the reaction tank to form a first test sample; the immune reagent supplying part is used for adding the immune reagent into the first test sample to form a second test sample; the light irradiation unit provides irradiation light; the control unit is used for controlling the temperature of the reaction tank and controlling the hemolytic reagent supplying part, the sample injection part and the immune reagent supplying part to act according to a certain sequence; the transmission light detection unit is used for detecting absorbance of the first test sample; the scattered light detection unit is used for detecting the strength of scattered light of the second test sample; the analytical calculation unit is used for carrying out analytical calculation on the absorbance and the strength of the scattered light to obtain blood routine parameters and specific protein parameters.
Owner:MACCURA MEDICAL INSTR CO LTD
Hemolytic agent for blood leukocyte five-classification counting and application thereof
The invention relates to a hemolytic agent for blood leukocyte five-classification counting and an application thereof. The hemolytic agent comprises a hemolytic agent A and a hemolytic agent B. The hemolytic agent A comprises a polyoxyethylene nonionic surfactant, an organic acid, a quaternary ammonium salt cationic surfactant cosolvent, a stabilizing agent and an osmotic regulator; the hemolytic agent B comprises alkaline inorganic salt and an osmotic regulator. When compared with the result detected by a standard hemolytic agent produced by BeckmanCoulter company, the hemolytic agent of the invention has good correlation and high accuracy. Especially, when abnormal cells exist in a blood specimen, the hemolytic agent has high warning sensitivity and good specificity, and exhibits the most beneficial effect.
Owner:GENERAL HOSPITAL OF PLA
Fluid system of flow cytometer and flow cytometric detection method
The invention discloses a fluid system of a flow cytometer and a flow cytometric detection method. The fluid system comprises a sampling needle, a sampling needle cleaning device, a flowing chamber, a reaction tank, a hemolytic agent syringe, a sample syringe, a diluent syringe, a diluent bottle, a hemolytic agent bottle and a motor, wherein the sample syringe is respectively communicated with the sampling needle, the reaction tank, the flowing chamber, the sampling needle cleaning device and the diluent syringe, the diluent syringe is respectively communicated with the diluent bottle, the flowing chamber and the reaction tank, the hemolytic agent syringe is respectively communicated with the hemolytic agent bottle and the reaction tank, and the hemolytic agent syringe, the sample syringe and the diluent syringe are all driven and controlled by the motor. According to the invention, driving motors for a plurality of syringes are integrated into one, arrangement of the syringes satisfies moment balance, integral rigidity and inertia are improved, gap instability of the driving motor can be buffered, a more stationary sample flow can be obtained, and thus, detection precision of the flow cytometer is improved.
Owner:SHENZHEN DYMIND BIOTECH
Method of classifying and counting leucocytes
ActiveUS20080176274A1Low costAccurate classificationMicrobiological testing/measurementIndividual particle analysisStainingWhite blood cell
Owner:SYSMEX CORP
Blood analyzer, blood analysis method, and computer program product
ActiveCN102768179AScattering properties measurementsIndividual particle analysisBlood specimenHemolytic Agents
A blood analyzer, a blood analysis method, and a computer program product that can distinguishably detect abnormal lymphocytes, blasts, and atypical lymphocytes are provided. A blood analyzer prepares a first measurement sample from a first reagent containing a hemolyzing agent, a second reagent containing a fluorescence staining dye, and the blood specimen, and prepares a second measurement sample from a third reagent containing a hemolyzing agent, a fourth reagent containing a fluorescence staining dye, and the blood specimen. The blood analyzer measures each of the measurement samples, and distinguishably detects abnormal lymphocytes, blasts, and atypical lymphocytes in a blood specimen based on the measurement data.
Owner:SYSMEX CORP
Flow cytometry detection fluid circuit system and flow cytometry detection method
ActiveCN104897557AReduce in quantityMiniaturizationIndividual particle analysisDiaphragm pumpInjection port
The invention relates to the technical field of human blood detection. A flow cytometry detection fluid circuit system comprises a diluent injection system, a hemolysin and blood sample injection system and a pressure system, wherein for the diluent injection system, a diluent injector is driven by a motor, and the diluent injection system is connected with a diluent barrel to suck a diluent to inject to a flowing chamber, a reaction tank and a sampling needle cleaning device; for the hemolysin and blood sample injection system, a hemolytic agent injector is driven by a motor, the hemolysin and blood sample injection system is used for sucking the hemolytic agent to inject to the reaction tank, and the sample injection sucking collects a distribution blood sample to inject to the reaction tank; for the pressure system, a diaphragm pump is connected with a pressure chamber to form positive and negative pressures, the pressure system is used for pumping waste liquid of the sampling needle cleaning device, sucking a sample in the reaction tank to a sample injection port of the flowing chamber, carrying out gas blowing stirring and evacuation on the reaction tank, and pumping the diluent to the reaction tank. According to the invention, the number of reaction tanks is reduced, system structure and complexity are simplified, and miniaturization and low cost are realized for machines.
Owner:GUANGZHOU EXCBIO TECH CO LTD
Agent for blood cell analyzer
The invention belongs to agents for medical diagnostic apparatuses, and in particular relates to an agent for a blood cell analyzer. The agent for the blood cell analyzer consists of a diluent, an EOI hemolytic agent, an LH hemolytic agent, an EOII staining solution and a cleaning solution. The agent for the blood cell analyzer is wide in range of use, suitable for many types of machines, suitable for detectors with machine types of BC5100 / 5180 / 5300 / 5380 / 5310 / 5390 and the like, and stable and accurate in detection result; the R value of a correlation coefficient after linear regression reaches more than or equal to 0.99 compared with a Mairui original blood cell agent and expresses relatively good relativity; and moreover, the agent is rich in raw material and low in price, and the raw materials are nontoxic and harmless and do not have threats on operators, so that the burden of the environment is lightened, and the raw materials are beneficial for popularization and application of the agent for the blood cell analyzer.
Owner:ZHONGSHAN CHUANGYI BIOCHEM ENG
Reagent for hemocyte analyzers
The invention discloses a reagent for hemocyte analyzers, which is prepared from diluent, hemolytic agent, sheath flow liquid and cleaning fluid. Compared with the prior art, the invention changes the actual state of long-term dependence on import of the reagent for hemocyte analyzers in China, and is produced and sold in China, thereby greatly reducing the production cost; the hemolytic agent in the reagent does not contain cyanogen, thereby greatly reducing the injury to health of the personnel and experiment operators in manufacturing factories, and avoiding the environment pollution of prussiates; the reagent is especially suitable for the CD3700 / 3500, CD3000 and CD3200 differential count full-automatic hemocyte analyzers of Abbott Laboratories in America, and the hemolytic agent A750test indicates the reagent achieves the ICSH standard; and the correlation coefficients of leucocyte, erythrocyte, hemoglobin, thrombocyte and the like relative to the imported ABBOTT CELL-DYN3700 / 3500 reagent are respectively greater than 0.95.
Owner:URIT MEDICAL ELECTRONICS CO LTD
Hemolytic agent, leucocyte classification reagent system and classification method
The invention relates to a hemolytic agent for a blood cell analysis device. The hemolytic agent is capable of cracking the erythrocytes in the blood, and the blood with cracked erythrocytes can be used for hemoglobin concentration determination. In addition, the invention also relates to a leukocyte classification reagent system which comprises the hemolytic agent and an inhibitor. After the hemolytic agent cracks the erythrocytes, the inhibitor can be added into the blood to prevent the hemolytic agent from damaging the morphology and structure of the leucocytes. Furthermore, the invention also relates to a method of classifying the leucocytes by using the reagent system.
Owner:SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD +1
Liquid-based cell preservation liquid composite and preparation method thereof
InactiveCN102318597AKeep shapeImprove diagnostic accuracyDead animal preservationFood additiveSodium diacetate
A liquid-based cell preservation liquid composite is characterized by comprising the following components in percentage by weight: cell fixing agent: 2-15% of formaldehyde, preservative: 0.1-5% of sodium diacetate, anticoagulant: 2-10% of sodium citrate, buffering agent: 0.5-2% of sodium chloride, chelating agent: 0.002-0.5% of ethylene diamine tetraacetic acid (EDTA), hemolytic agent: 0.5-10% ofglacial acetic acid, and water: 5-80% of pure water, wherein the formaldehyde is the analytical reagent, and accounts for 37-40%; the sodium diacetate is the food additives; the sodium citrate and the sodium chloride are analytical reagents, and NaCl is more than 99.5%; and the EDTA and the glacial acetic acid are analytical reagents, and H2COOH is more than 99.5%. The invention has the advantages that the liquid-based cell preservation liquid composite can keep the cell form to the maximum extent, can improve the diagnosis accuracy and can prevent the cell form of a specimen from significantdifference at room temperature for at least three months.
Owner:上海鎏轶生物技术中心
Hemolytic agent and application thereof as well as classifying and counting method for white blood cells
InactiveCN104297134ASimple componentsEasy to useIndividual particle analysisBasophilic GranulocyteWhite blood cell
The invention relates to the technical field of medical examination and discloses a hemolytic agent and application thereof as well as a classifying and counting method for white blood cells. The hemolytic agent contains one or more than two kinds of cationic surfactants, one or more than two kinds of small molecule alcohols, one or more than two kinds of buffer solutions, one or more than two kinds of soluble inorganic salts and the balance of water. According to the invention, components of the hemolytic agent are simplified; the novel hemolytic agent suitable for classifying and counting basophilic granulocyte and other white blood cells is prepared by adopting the raw materials which are proper and easy to obtain; compared with the current hemolytic agent product with more complex components, the hemolytic agent disclosed by the invention is more convenient and quicker for use; the hemolysis time only needs 5-20s, the classifying and the counting for the basophilic granulocyte and the other white blood cells can be realized by combining the hemolytic agent with an impedance analysis measuring instrument without special requirement on the temperature, and the accuracy is higher.
Owner:SONOSCAPE MEDICAL CORP
Fluid system of flow cytometer and flow cell detecting method
ActiveCN104127192APush sample flow is smoothExtended service lifeDiagnostic recording/measuringSensorsFlow cellHemolytic Agents
The invention discloses a fluid system of a flow cytometer and a flow cell detecting method. The fluid system of the flow cytometer comprises a sheath flow injector, a sample flow injector, a blood sampling injector, a hemolytic agent injector, a blood sampling needle, a reaction tank, a flowing chamber, a diluent barrel, a hemolytic agent bottle, a first motor, a second motor and a third motor, wherein the sheath flow injector is driven by the first motor; the hemolytic agent injector is driven by the third motor; and the sample flow injector and the blood sampling injector are driven by the second motor. The sample flow injector and the blood sampling injector share the second motor, and are arranged in a moment balancing manner; the second motor is arranged between the two injectors; the cost of the system is reduced; the whole rigidity and the inertia of the system are also improved; sample flow is pushed by the injector stably; and the detection accuracy is improved.
Owner:SHENZHEN DYMIND BIOTECH
Flow cytometry fluid path system and flow cytometry method
InactiveCN104914031AAvoid jitterMiniaturizationIndividual particle analysisSolenoid valveEngineering
The invention relates to the technical field of human blood detection and discloses a flow cytometry fluid path system. The system consists of a motor drive sample stream injector and a sheath fluid injector, wherein the outlet of the sample stream injector is respectively connected with a diluent bucket and a sample injection port by virtue of a pipeline and a three-way solenoid valve and is also connected with a reaction tank; the outlet of the sheath fluid injector respectively passes through a two-way solenoid valve by virtue of a pipeline and a liquid pressure sensor and is connected with a flow chamber sample injection port, a flow chamber sheath fluid injection port and a fluid suction port of the sample stream injector; a hemolytic agent injector is driven by the motor, and the outlet of the hemolytic agent injector is respectively connected with a hemolytic agent bottle and the reaction tank by virtue of a pipeline and a three-way solenoid valve; the outlet of a sampling injector is connected with a sampling needle by virtue of a pipeline; and a diluent injection port in the sampling injector is connected with the diluent bucket by virtue of a pipeline. The system disclosed by the invention is simple in structure, low in cost and simple and reliable in detection method, the detection data is accurate, and machine miniaturization can be realized.
Owner:GUANGZHOU EXCBIO TECH CO LTD
Simple and reliable hemocyte five-class analysis method, system and device
InactiveCN105699635AGuaranteed Count ResultsDoes not affect classification stability due to mixed crossoversBiological testingPlatelet countingMedicine
The invention discloses a simple and reliable method, system and device for five-classification analysis of blood cells, including a white blood cell counting pool, a red blood cell and platelet counting pool, a five-classification detection device, a hemoglobin detection device, and a red blood cell detection device. The device divides blood samples and corresponding reagents into the two counting pools for reaction. It is characterized in that the system is equipped with two kinds of hemolysis agents, namely the first hemolysis agent and the second hemolysis agent, and the white blood cell four-category count and basophil The count is measured twice by the five-differential detection device, and the four-differential count and the total white blood cell count are realized by mixing the first hemolytic agent with the blood sample; the basophilic count is realized by mixing the second hemolytic agent with the blood sample added with diluent cell counts. The invention can realize low cost and small volume, and the accuracy of basophils can reach the level of high-end five-differentiation blood cell analyzer, which is more suitable for use in primary hospitals.
Owner:SHENZHEN DYMIND BIOTECH
Immunoturbidimetric kit for detecting procalcitonin
InactiveCN107340395AReduce dosageHigh detection sensitivityScattering properties measurementsBiological testingHemolytic AgentsMicrosphere
The present invention relates to the field of medical immunology, particularly to an immunoturbidimetric kit for detecting procalcitonin. The kit comprises a reagent R1 and a reagent R2, wherein the reagent R1 comprises a buffer liquid, a stabilizer, a protection agent, a coagulant, a hemolytic agent and a preservative, the reagent R2 comprises a buffer liquid, a stabilizer, a protection agent, a preservative and a polystyrene latex microsphere-procalcitonin antibody complex, and the polystyrene latex microspheres comprise two types of microspheres such as microspheres having a particle size of 80-150 nm and microspheres having a particle size of 150-400 nm. According to the present invention, the test results show that the kit has advantages of good stability and long storage period, can directly detect the PCT in whole blood, and further has advantages of high detection result accuracy, high sensitivity and wide linear detection range.
Owner:SONOSCAPE MEDICAL CORP
Method for seperating and purifying RNA
ActiveUS20090143572A1Improve efficiencyHigh puritySugar derivativesMicrobiological testing/measurementOrganic solventHemolytic Agents
A method for separating and purifying RNA including the steps of passing a sample solution containing a nucleic acid, a washing solution and a recovering solution through a nucleic acid-adsorbing porous membrane to adsorb nucleic acid, adsorbing, washing and recovering, in which the nucleic acid adsorbing porous membrane is a porous membrane capable of adsorbing a nucleic acid by interaction involving substantially no ionic bond, and the sample solution is obtained by a process, comprising the steps of (I) injecting a test sample containing at least one of blood and leukocyte, and further containing an anticoagulant to a container, (II) adding a hemolytic agent to the container to obtain a leukocyte pallet, (III) adding a nucleic acid-solubilizing reagent to the leukocyte pallet to obtain a mixture solution and (IV) adding a water-soluble organic solvent to the mixture solution to obtain the sample solution containing the nucleic acid.
Owner:KURASHIKI BOSEKI KK
Leukocyte classification kit and classification method thereof
InactiveCN103424540AReduce consumptionReduce testing costsBiological testingFluorescence/phosphorescenceQuantum yieldImmature cells
The invention discloses a leukocyte classification and a classification method thereof, and the kit is composed of a water soluble quantum dots-cyanine dye probe, and an erythrocyte and platelet hemolytic agent, wherein the quantum dots-cyanine dye probe is composed of a stabilizing agent, which takes a polypeptides material as the quantum dots, and Cy5 cyanine dye covalent joint molecules whose emission spectrum is in the near infrared area, and has the characteristics of high quantum yield and sensitivity; the erythrocyte and platelet hemolytic agent can rapidly solves erythrocytes in the blood, and is composed of a cationic surfactant, a non-ionic surfactant, a pH buffer agent or combination of the cationic surfactant, the non-ionic surfactant, and the pH buffer agent. The leukocyte classification reagent provided by the invention can carry out precise subgroup identification on lymphocyte, monocyte, neutrophil, basophilic granulocyte, and acidophilic granulocyte in leukocytes of blood samples, and further identify immature cells or abnormal cells.
Owner:嘉善加斯戴克医疗器械有限公司
Hemolytic agent
ActiveCN101464453AReduce the effect of temperatureAmbient temperature requirements are lowBiological testingOrganic acidHemolytic Agents
The invention discloses a hemolytic agent which contains at least one organic acid whose content ranges from 1 to 20g / L, and relates to a multipurpose hemolytic agent, which can be used for automatic hemanalysis, and can accurately test hematoglobin and keep the normal classification of leucocyte at the same time. A stabilizing agent of hematoglobin derivants is added in the hemolytic agent, thereby preventing the derivants from changing along with the reaction temperature change, and ensuring that an accurate and stable test result can be obtained within the normal service temperature range of the instrument.
Owner:SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD +1
Hemolytic agent, method for pretreatment of biological sample, method for determining content of target substance, and kit
ActiveCN106546455AReduce the binding forceOptimize the reaction systemMaterial analysis by observing effect on chemical indicatorPreparing sample for investigationHemolytic AgentsTurbidimetry
The invention discloses a hemolytic agent, a method for pretreatment of a biological sample, a method for determining the content of a target substance, and a kit. The invention provides a use of a boric acid buffer system in preparation of the hemolytic agent, the hemolytic agent for immunological turbidimetry determination, the method for pretreatment of the biological sample, the method for determining the content of the target substance in the biological sample, and the kit for immunological turbidimetry determination. The hemolytic agent is used for immunological turbidimetry determination. When the hemolytic agent prepared by the boric acid buffer system is used for immunological turbidimetry determination, the hemolytic agent has at least one of the following advantages of high sensitivity, fast and simple detection process and strong specificity.
Owner:SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
Blood cell analyzer dilution as well as hemolytic agent
InactiveCN101281193AImprove working environmentReduce harmIndividual particle analysisBiological testingNon toxicityToxicant
A blood cell analyzer diluent and a hemolytic agent, are characterized in that one litre diluent is provided with 12.0-4.0g of sodium chloride, 2.0-10.0g of sodium sulfate, 0.8-0.5g of 1,3,2-methylol urea, 0.2-0.5g of copper sulfite, 3.0-8.0g of EDTA-2Na, 0.2-0.7g of Piperacillin Sodium, a borate buffering liquid toning the ph value to 7.2-7.8, and the balance is water; one litre hemolytic agent is provided with 0.8-5.0g of potassium chloride, 0-60.0g of dodecyl trimethyl ammonium chloride, 14.0-0g of octadecyl trimethyl ammonium bromide, 6.0-10.0ml of isopropanol, carbonate or alcaine buffering liquid toning the ph value to 7.2-7.8, and the balance is water. The inventive reagent can form stable hemoglobin derivatives, and the absorption spectrum curves are similar when lambada is 540nm, lambada is 504nm, which can satisfy the clinical inspection requirement; the reagent does not contain cyanide, azide, and has non-toxicity, which can effective improve working atmosphere of operating staff, and can reduce harm of toxicant to personal health.
Owner:南昌百特生物高新技术股份有限公司
Hemocyte analyzer hemolytic agent
The invention discloses a hemocyte analyzer hemolytic agent. Every 1L of hemolytic agent comprises 5-40.0g of quaternary ammonium salt, 5.0-25.0g of alkali metal chloride, 0.05-5.0g of ethylenediamine tetraacetic acid or ethylenediamine tetraacetic acid derivative, 0.5-5.0ml of inorganic acid, 0.5-8.0g of pH regulator for regulating the pH value to 5.0-8.0, and the balance of water. The invention solves the problem that the peak shapes of lymphocyte, monocyte and granulocyte in a leucocyte histogram of XFA6000-series and XFA6000 Intelligent-series full-automatic hemocyte analyzers produced by Nanjing Pulang Medical Equipment CO, LTD are not obvious or only the wave peaks of the lymphocyte and granulocyte can appear, and also solves a series of problems of insufficient accuracy of classification of leucocytes; and the reagent does not contain any preservative or cyanide, and thus, does not pollute the environment.
Owner:NANJING PERLONG MEDICAL EQUIP
Method for improving accuracy of blood sample leukocyte classifying result
ActiveCN101470109AGuaranteed accuracyDoes not affect count valueBiological testingCounting NumberMedicine
A method for improving the accuracy of leukocyte classifying result of blood sample comprises: A, in the counting process of leukocyte, adding hemolytic agent in two times, testing and obtaining a first leukocyte counting number after adding the hemolytic agent at first time and a first leukocyte histogram, and a second leukocyte counting number after adding hemolytic agent at second time, while the hemolytic dosage added in the first time makes red blood cell fragments left affecting the counting number of leukocyte in the blood sample, and the hemolytic dosage added in the second time makesno red blood cell fragments left to avoid affecting the counting number of leukocyte; B, according to the ratio between the first leukocyte counting number and the second leukocyte counting number, determining a leukocyte classification histogram, and classifying leukocytes. The method can confirm the accuracy of leukocyte counting number and hemoglobin test result, and can improve the classification accuracy of leukocyte of animal blood samples of dog, cat and the like.
Owner:深圳迈瑞动物医疗科技股份有限公司
Blood analyzer and blood analysis method
Owner:SYSMEX CORP
Kit for detecting serum amyloid A content and preparation method and detection method thereof
InactiveCN108828225AShort detection timeApplicable outpatientMaterial analysis by observing effect on chemical indicatorBiological material analysisSERUM AMYLOID A2Serum ige
The invention provides a kit for detecting serum amyloid A content and a preparation method and detection method thereof and belongs to the field of medical detection. The kit comprises a hemolytic agent R1 and a latex reagent R2 which are independent with each other. The latex reagent R2 comprises latex coated with a serum amyloid A antibody. The latex coated with the serum amyloid A antibody isprepared from latex having particle sizes of 60-130nm and coated with the anti-serum amyloid A1 antibody and latex having particle sizes of 190-220nm and coated with the anti-serum amyloid A2 antibodythrough mixing. The invention also provides a preparation method and a detection method of the kit for detecting serum amyloid A content. The kit can detect whole blood, serum, a cerebrospinal fluidand a pleuroperitoneal fluid, utilizes a small amount of samples, is free of separation or pretreatment, can be directly used for detection and has good sample compatibility.
Owner:DIRUI MEDICAL TECH CO LTD
White blood cell classification reagent
PendingCN108414427ASave raw materialsImplement classificationIndividual particle analysisRed blood cellNeutrophil granulocyte
The invention discloses a white blood cell classification reagent, which comprises the following raw materials: an ionic surfactant, a pH value adjusting buffer, an alkali metal salt for adjusting osmotic pressure, and an alcohol capable of dissolving and accelerating. According to the present invention, with the white blood cell classification reagent, white blood cells can be divided into four cell clusters, and the boundary between each cell cluster is clear; compared to the traditional five-class hemolytic agent, the white blood cell classification reagent of the present invention has thefollowing advantages that the boundary between the monocyte clusters and the neutrophil cluster is clear, and the clustering property is strong; the white blood cell classification reagent has characteristics of strong low-temperature hemolysis ability and wide temperature range, and can rapidly dissolve red blood cells in a low-temperature environment, ensure the normal classification of white blood cells, and reduce the manufacturing cost of the instrument on temperature control; and the white blood cell classification reagent further has advantages of low raw material cost, environmental protection and no toxicity, and can classify white blood cells by requiring only one reagent so as to achieve advantages of convenience, time saving and reduced production cost.
Owner:SHENZHEN DYMIND BIOTECH
A multifunctional support
PendingCN106388945AHeating or cooling apparatusSurgical furnitureTemperature controlHemolytic Agents
The invention provides a multifunctional support comprising a blood collecting needle, blood collecting bottle and reagent bottle support, which is used for storing blood collecting needles, blood collecting bottles and reagent bottles, wherein the blood collecting bottles can be heated and the reagent bottles can be refrigerated. A refrigeration area of the blood collecting needle, blood collecting bottle and reagent bottle support is mainly used for refrigerating reagents (including antibody reagents) requiring refrigeration, wherein an ice storage area can cool the refrigeration area on the condition of the power failure to prevent the reagents requiring refrigeration from losing efficacy at high temperature. A normal temperature area of the blood collecting needle, blood collecting bottle and reagent bottle support is used for storing reagents and solutions stored at normal temperature, such as diluents, cleaning fluid and hemolytic agents. A blood collecting needle and blood collecting bottle storage area is provided with a blood collecting needle support, a blood collecting bottle bracket, blood collecting bottle bracket guide rails, a video camera device, a limit switch and a temperature control device.
Owner:BEIJING HUAWEI YINGYUN TECH & DEV CO LTD
Immune cytometer fluid system
InactiveCN108732081AExtended service lifeImprove detection accuracyBiological particle analysisIndividual particle analysisExtensibilityBlood Collection Tube
The invention discloses an immune cytometer fluid system which is characterized by comprising a sample flow and blood collection injection syringe, a hemolytic agent injection syringe, a sampling needle cleaning injection syringe, a sheath flow injection syringe, a sampling needle cleaning tank injection syringe, a blood collection needle, a reagent collection needle, a negative pressure chamber,a blood collection needle cleaning tank, a reagent collection needle cleaning tank, a reaction tank, a reagent storage bin, a flow chamber, a filter, a negative pressure sensor, a waste liquid tank and a diluent barrel, wherein each of the devices are connected through pumps, valves, joints and tubes, to form the complete cytometer fluid system. The immune cytometer fluid system can be adopted todetect small molecule items and expanded to the detection of bacteria and other items, and has the advantages of high sensitivity, good project extensibility, convenience in operation and high efficiency.
Owner:SHENZHEN DYMIND BIOTECH
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