The invention relates to a tumor imaging quantitative detection technology, in particular to a method for quantitatively measuring a tumor standard uptake value, a thin body standard uptake value, a metabolic volume and total glucolysis through Coincidence SPECT or SPECT/CT and application of the method in tumor assessment. The implementation steps of the method comprise an image acquisition step, a scatter correction step, a nuclide physical decay correction step, a movement correction step, a tissue attenuation correction step, an image spatial resolution recovery step, a noise removal step, a standard uptake value calculation step and a tumor therapeutic effect assessment step. By means of the technological means of the Coincidence SPECT tumor imaging quantitative analysis technology and the application in tumor assessment, the clinical problem of quantitatively measuring the tumor standard uptake value, the thin body standard uptake value, the metabolic volume and the total glucolysis is solved through the Coincidence SPECT and the SPECT/CT, and the technology can be used in the clinical assessment of tumor.