The application provides a high-brightness fluorescent dye for
lipid droplet labeling and synthesis and application thereof, the fluorescent dye taking 1-acetyl
pyrene as a
parent body, and introducing a
diphenylamine substituent group at 8, as shown in the following formula (1). The probe can specifically
label lipid droplets in living cells, and has the advantages of high brightness, high
signal-to-
noise ratio, rapid labeling and the like. The
lipid droplet dye has a very broad application prospect in
dynamic imaging and real-time monitoring of lipid droplets.