The invention discloses a liquid crystal display (LCD) device and an image signal processing method applied to the LCD device. The LCD device comprises a decoding module, a dynamic backlight control module, a time sequence control module, a liquid crystal driving module, an LCD panel, a backlight driving module and an LED backlight module, wherein the dynamic backlight control module is connectedwith the decoding module and is used for receiving an image RGB grey scale signal, carrying out gamma correction on the RGB grey scale signal and statistics on the average value and the standard deviation, calculating to obtain the backlight adjusted value, calculating a backlight brightness signal according to the reference brightness value which is preset or input by a user, and outputting the backlight brightness signal to the backlight driving module to drive the LED backlight module to lighten the LCD panel. The invention also discloses the corresponding image signal processing method. The device and the method can effectively reduce the power consumption, increases the contrast, avoids the situation of ultra-low backlight brightness when the image is monochrome image with less standard deviation, and improves the display effect.