18 results about "Blood preservation" patented technology

The utility model relates to the technical field of blood preservation, in particular to a stable preservation liquid device for preserving plasma free DNA for a long time, which comprises a preservation liquid device main body, the upper surface of the preservation liquid device main body is fixedly connected with a supporting material receiving shell, and the inner ring surface of the supporting material receiving shell is fixedly connected with a mounting block. And an extended threaded rod is inserted into the surface of the inner ring of the mounting block in a limiting manner. According to the stable preserving fluid equipment for preserving plasma free DNA for a long time, a preserving test tube can be clamped through a fixing plate, the temperature can be adjusted after ice blocks are added into a supporting material collecting shell, and after the temperature is adjusted, a pull handle needs to be pulled, so that the preserving fluid equipment can be used for preserving plasma free DNA stably. And then a user can take down the piston from the supporting material collecting shell, so that ice blocks in the supporting material collecting shell can be replaced, and the preserving fluid equipment can be conveniently transferred to a site through a plurality of universal wheels fixedly connected to the surface of the bottom of the preserving fluid equipment main body and an operation handrail.

The invention discloses a blood preserving fluid suitable for preserving immune cells, which is composed of the following components in terms of 100 ml: 1 to 5 g of glucose, 2 to 4 mg of glutathione, 0.2 to 0.4 g of citric acid, 0.1 to 0.3 g of sodium dihydrogen phosphate, 1 to 3 g of sodium citrate, 8 to 12 mg of sodium ferulate, and 8 to 12 mg of notoginsenoside. The composition comprises L-glutamine, L-arginine, L-aspartic acid, L-histidine, L-glutamine, L-arginine, L-aspartic acid, L-histidine and the like, and the balance of sterile water. By optimizing the formula of the preserving fluid, the stability of the PBMC in the transportation process is specifically maintained, granulocyte activation and pollution are effectively inhibited, immune cell apoptosis is reduced, the multiplication capacity and the cell factor secretion function of the immune cells are maintained, and the recovery rate and activity of the immune cells after long-distance transportation are remarkably improved.

The application discloses a self-mixing blood RNA storage tube and a use method, and belongs to the field of biomedical sample storage devices. The tube body is pre-stored with RNA stabilizing liquid, and the opening end is provided with a rotating sealing cover. The tube body is provided with a double-helix flow guide pipe, and the RNA stabilizing liquid is pre-installed at the bottom of the double-helix flow guide pipe. When blood flows into the tube body, the blood rotates and flows along the spiral flow guide pipe and is automatically mixed. The application sets the double-helix flow guide pipe in the tube body, and directly pre-installs the RNA stabilizing liquid at the bottom of the double-helix flow guide pipe, so that the blood rotates and flows along the spiral path after entering the tube body, the blood is fully contacted and uniformly mixed with the RNA stabilizing liquid in a short time, an additional mixing step is not needed, operation errors are reduced, the RNA storage conditions of all blood sampling samples are ensured to be consistent, and the stability of experimental data is improved. Through the cooperative design of the sealing rubber plug and the rotating sealing cover, the air tightness of the blood before entering the tube body is ensured, and external pollution is prevented.

The invention relates to the technical field of blood miRNA preservation, and particularly discloses a disposable blood miRNA preservation tube and a preservation solution thereof, the preservation solution is composed of the following components: 30 mg / ml of glycine, 3 mg / ml of glutamine, 3 mg / ml of glucose, 600 mg / ml of sodium orthovanadate, 3 mg / ml of aluminum fluoride, 25 mg / ml of acetylcysteine, 300 mg / ml of diazoalkyl urea, 2.0 mg / ml of EDTA-2Na, 6 mg / ml of sorbitol, 6 mg / ml of trehalose, and the balance of water. The preservation tube is good in sealing performance and convenient to use, the preservation liquid can effectively slow down rupture of blood cells, DNA in the blood cells is prevented from diluting and polluting target miRNA, nuclease is prevented from degrading the target miRNA, and the preservation period of a blood sample containing target nucleic acid is prolonged.

Described herein are blood storage containers that can contain a CeONP composition and / or coating on an object surface. In some aspects, the blood storage container can include an insert. In some aspects the inserts can contain a CeONP compositions and / or coating on an object surface. In aspects, the CeONP composition and / or coating on an object surface can be effective to increase the useful storage lifespan of blood, blood product, and / or component thereof stored in the blood storage container. Also described herein are methods of making and using the CeONP compositions, coatings, and devices containing the CeONP compositions and / or coatings described herein.

The utility model provides a portable blood storage and transportation box, which relates to the technical field of blood transportation and comprises a storage and transportation box whole body, an equipment box is mounted on the right side surface of the storage and transportation box whole body, a storage box is fixedly connected to the left side surface of the equipment box, and a heat preservation layer is fixedly connected to the inner side of the storage box. The inner side of the heat preservation layer is fixedly connected with an inner container layer, conveying openings are symmetrically formed in the positions, close to the top, of the right side wall of the inner container layer and communicated with the equipment box, partition plates are connected into the inner container layer in a clamped mode, clamping rings are fixedly connected into the partition plates, and the clamping rings are used for fixing the tubular blood container. The blood can be well stored, and the storage equipment can be effectively and conveniently carried, so that the blood storage equipment is very convenient.

Described herein are blood storage containers that can contain a CeONP composition and / or coating on an object surface. In some aspects, the blood storage container can include an insert. In some aspects, the inserts can contain a CeONP composition and / or coating on an object surface. In aspects, the CeONP composition and / or coating on an object surface can be effective to increase the useful storage lifespan of blood, blood product, and / or component thereof stored in the blood storage container. Also described herein are methods of making and using the CeONP compositions, coatings, and devices containing the CeONP compositions and / or coatings described herein.

The invention discloses a self-mixing blood RNA preservation tube and a use method, and belongs to the field of biomedical sample preservation devices. Wherein RNA stabilizing liquid is pre-stored in the tube body, and a rotary sealing cover is arranged at the opening end of the tube body; a double-helix guide tube is arranged in the tube body, RNA stabilizing liquid is preloaded at the bottom of the double-helix guide tube, and when blood flows into the tube body, the blood rotationally flows along the spiral guide tube and is automatically mixed with the spiral guide tube. The double-helix guide tube is arranged in the tube body, and the RNA stabilizing solution is directly preloaded at the bottom of the double-helix guide tube, so that blood is ensured to rotationally flow along a spiral path after entering the tube body, the blood and the RNA stabilizing solution are fully contacted and uniformly mixed within a short time, an additional mixing step is not needed, the operation error is reduced, and the operation efficiency is improved. The consistency of RNA preservation conditions of all blood sampling samples is ensured, and the stability of experimental data is improved; through the collaborative design of the sealing rubber plug and the rotary sealing cover, the air tightness of blood before the blood enters the tube body is ensured, and external pollution is prevented.

The invention belongs to the technical field of blood storage boxes, and particularly relates to a portable intelligent blood storage box and a using method thereof.The portable intelligent blood storage box comprises a box body, handles are fixedly arranged on the two sides of the box body, a first supporting net plate and a second supporting net plate are fixedly installed on the inner wall of the bottom of the box body, and a supporting mechanism is arranged in the box body; the supporting mechanism can support different blood; a base mechanism is arranged at the bottom of the box body and used for supporting the ice bags. The blood storage box has the beneficial effects that the first supporting assembly is arranged in the blood storage box and used for storing and transferring blood bags needing to be vibrated, and the second supporting assembly is arranged, so that blood bags and blood vessels not needing to be vibrated are conveniently stored and transferred; therefore, different blood samples can be conveniently distinguished and stored.

The present invention discloses a platelet ultrastructure imaging detection sample processing reagent, comprising a diluent; the ratio of the diluent, blood preservation solution and benchtop solution is 1:7 to 12. The present invention also provides a platelet ultrastructure imaging detection sample processing kit, comprising the sample processing reagent of the present invention, preferably also including a fixative, the fixative comprising 4% to 8% paraformaldehyde by volume, and the solvent comprising a PHEM buffer solution with a pH of 6.8 to 7.2, wherein the platelet microtubule structure fixative preferably comprises 5.5% to 6.6% paraformaldehyde, 0.05% to 0.15% glutaraldehyde and 0.1% to 0.2% TritonX-100 by volume. In addition, the present invention also provides a platelet ultrastructure imaging detection sample processing reagent for use in preparing imaging detection samples, wherein the diluent is first added to the platelet plasma obtained by centrifugation, and the platelets are then fixed after being allowed to stand for recovery after dilution, thereby obtaining unactivated platelets, so that the test results are closer to the true condition of platelets under physiological conditions.

The utility model relates to the technical field of medical instruments, in particular to a constant-temperature cushioning anti-hemolysis blood storage and transportation device which comprises a transportation box body. The containing cabin is arranged in an inner cavity of the transport case body and slidably connected with an inner cavity of the containing cabin, the containing cabin comprises an anti-coagulation tube storage bin and a constant-temperature bin arranged at the bottom of the anti-coagulation tube storage bin, and a constant-temperature assembly is arranged in the constant-temperature bin; the anticoagulation tube storage device comprises rotating shaft rotating pieces symmetrically arranged on the two side walls of the anticoagulation tube storage bin, a rotating shaft connected with the two rotating shaft rotating pieces, and an anticoagulation tube storage tube arranged on the rotating shaft and connected with the rotating shaft through a universal rotating piece. The cushioning assembly comprises a first cushioning piece arranged on the upper end face of the containing cabin, a second cushioning piece arranged between the lower bottom face of the containing cabin and the bottom of the transport box body and a third cushioning piece wrapping the periphery of the rotating shaft rotating piece.

The invention discloses a multi-union blood bag capable of removing white blood for preserving blood of cats and dogs, which relates to the field of multi-union blood bags for animals and comprises a blood collection bag, a blood taking needle connected with a blood inlet of the blood collection bag, a filtered blood bag connected with a blood outlet of the blood collection bag, and a red blood cell preserving fluid bag connected with the filtered blood bag. The leukocyte filter is arranged between the blood collection bag and the filtered blood bag, the mixing structure is arranged between the blood collection bag and the blood taking needle and can realize mixing of collected blood and an anticoagulant, the anticoagulant bag is connected with the mixing structure, and the one-way control structure is arranged between the anticoagulant bag and the mixing structure; according to the multi-union blood bag capable of removing white blood and used for cat and dog blood preservation, through the mixing structure and the one-way control structure, instant and sufficient mixing of blood and anticoagulant is achieved, and therefore the problems that anticoagulation is delayed and the microclot forming probability is high are solved, and the blood collection quality and preservation safety are improved.

The invention discloses a blood preservation composition, a blood preservation material, a blood preservation bag and a preparation method and application thereof. When the composition is added into a red blood cell suspension, long-acting slow release of adenine can be achieved, the ATP synthesis capacity of red blood cells in the storage period is improved, the storage quality of the red blood cells is improved, and then the infusion effectiveness of the red blood cells is improved. The method for preparing the composition and the blood preservation material is simple in process and low in cost.

The utility model relates to the technical field of storage systems, and discloses a rapid code scanning device and a blood preservation storeroom, the rapid code scanning device comprises an object carrying frame, a camera shooting assembly and a detection assembly, the object carrying frame is provided with a plurality of placing positions, and the placing positions are used for placing storage boxes; the camera shooting assembly is used for identifying the storage box and the position of the storage box in the carrying frame; the detection assembly is used for detecting whether the storage box exists in the placement position. The code scanning device provided by the utility model can quickly identify the storage box and can accurately locate the position of the storage box in the object carrying frame at the same time.

The invention discloses a field emergency blood sampling device convenient to operate, and belongs to the technical field of medical instruments. The device comprises a shell and a top cover connected with the shell in a sleeved mode, a left clamping base and a right clamping base are arranged at the top of the shell, and a lead screw drives the right clamping base to move so as to fix an arm; a fixing column is installed on the front side of the left clamping seat and sleeved with a movable supporting column and a sliding arm, a fixing needle seat is arranged at the end of the sliding arm, a sliding sleeve is embedded in an inclined clamping hole in the needle seat to fix a blood taking needle, and a positioning groove is combined to assist in accurately puncturing a blood vessel. A refrigeration sheet and a temperature sensor are arranged in the storage box to preserve blood at low temperature, and a top manual negative pressure pump is connected with a blood bag through a catheter to assist blood collection; a sterilizing lamp is arranged in the top cover, a solar panel covers the top cover, and field power supply is achieved by combining a mobile power source. Through the functions of clamping and fixing, directional puncture and low-temperature preservation, the operation difficulty of non-professionals is simplified, safety and convenience in the field environment are ensured through solar power supply and ultraviolet sterilization, and the emergency blood sampling efficiency and the blood preservation quality are remarkably improved.

The invention provides an in-tube additive for a cfDNA vacuum blood collection tube and the blood collection tube. The in-tube additive comprises an anticoagulant, a preservative, a cell protective agent, an enzyme inhibitor, a metabolic inhibitor and an antioxidant, the enzyme inhibitor comprises a nuclease inhibitor; the nuclease inhibitor comprises an anti-deoxyribonuclease antibody; and the anti-deoxyribonuclease antibody comprises at least one of an anti-DNASE1 antibody and an anti-DNASE1L3 antibody. According to the in-tube additive of the cfDNA vacuum blood collection tube, cfDNA can be stably stored, and the hemolysis phenomenon in the blood storage process can be effectively improved.

To provide a novel oxygen reduced blood product.SOLUTION: An oxygen reduced blood product has a final concentration of approximately 0.2 mM amustaline (S-303), having an oxygen saturation (SO2) of less than 25%, and a carbon dioxide partial pressure (pCO2) of 90 mmHg or less at 37°C.SELECTED DRAWING: Figure 1