30 results about "Domain combination" patented technology

Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and / or immuno-domains, selected monomer and / or immuno-domains, multimers and / or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.

The invention provides a method for estimating parameters of a space stretching electromagnetic vector sensor array. The method comprises the steps of receiving K unrelated incoming signals through a receiving array, and constructing guide vectors of the incoming signals corresponding to the array; expressing the guide vectors of the incoming signals as a product of a spatial domain function array and a polarizational domain function vector; computing a covariance matrix of the received data; analyzing features of the covariance matrix of the received data to obtain signal subspace and noise subspace; constructing a multi-signal classified MUSIC spatial-polarizational domain combination zero spectrum function, and maximizing the spatial-polarizational domain combination zero spectrum function; performing MUSIC dimension reduction process to separate a spatial domain spectrum and a polarizational domain spectrum by means of the self-conjugate moment Rayleigh-Ritz entropy theorem, performing traversal search within value ranges of variables and estimating signal parameters. By means of the method, four-dimensional MUSIC search is transformed into two-dimensional spatial domain search and two-dimensional polarizational domain search, and therefore, calculated quantity is decreased.

Methods of treating cancer comprising administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and / or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are provided. Dosage packs comprising an FGFR1 ECD and / or an FGFR1 ECD fusion molecule and / or at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are also provided. In some embodiments, a dosage pack comprises instructions for administering FGFR1 ECD and / or FGFR1 ECD fusion molecule with at least one additional therapeutic agent.

The invention belongs to the technical field of HEVC (High Efficiency Video Coding), and discloses a code rate control method based on a subjective region of interest and time-space domain combination. The method comprises the following steps: calculating each CTU grade target bit allocation weight based on a space domain; calculating a motion region of each frame of image based on light streams and a global motion estimation algorithm to serve as a time domain region of interest; adjusting the obtained CTU grade target bit allocation weights according to a time domain region of interest result obtained on the basis of the light streams and the global motion estimation algorithm; performing a center enhancing operation on the CTU grade target bit allocation weights obtained through time-space domain subjective region of interest detection; obtaining final coding CTU grade target bit allocation to perform a coding operation; and modifying a video compression final evaluation standard. Compared with an HM16.0 compression model, the code rate control method has the advantages that the HEVC compression subjective effect is enhanced under the condition of ensuring that a target bit code rate is invariable.

The present invention relates to a system and a method for quickly and accurately identifying and classifying resistance genes of a plant from a protein or DNA sequence. In order to identify and classify resistance genes of a plant using a hidden marcov model, conceived is a profile matrix made using a protein sequence of a domain which is encoded by the resistance genes, and a system for identifying the domain of the resistance genes using the profile matrix and classifying the resistance genes by domain combination. The present invention enables effective identification and classification of the resistance genes of a plant using the profile matrix and program, of which the nucleotide base sequence or protein sequence is detected.

The invention discloses a pseudo-satellite indoor positioning method based on fusion of a pseudorange observation value and a carrier-to-noise ratio. The method comprises: step one, for an asynchronous pseudo-satellite indoor positioning system, giving a positioning equation based on a weighted centroid localization algorithm; step two, carrying out calculation by using a pseudo-satellite carrier-to-noise ratio value received by a receiver to obtain a weight value; step three, carrying out fusion of pseudorange and the carrier-to-noise ratio observation values, adding a redundant observation value, and carrying out observation value domain combination, thereby improving the accuracy and reliability of the positioning; and step four, carrying out positioning solution by using a unscented Kalman filter (UKF). According to the invention, phenomena of unsynchronization of sampling time of receivers and occurrence of multipath errors can be suppressed; a good positioning effect can be realized under the condition of poor pseudo-satellite geometric distribution; and the good anti-gross-error performance is realized. The pseudo-satellite indoor positioning method can be applied to the deep indoor scene.

The invention discloses a multi-color grade image connected domain-based segmentation and mark method and device. The method comprises the following steps of: preprocessing an image to ensure that image color lumps of two or more color grades are divided from the image; obtaining pixel point data of the image color block of each color grade; respectively finding out a connection line formed by pixel points which are continuously connected in at least two preset directions according to the pixel point data so as to obtain a sub-segments, and marking numbers for the sub-segments; recording segment numbers of one or more sub-segments where the pixel points are located in the pixel point data; combining the segment numbers according to a preset connected domain combination rule, considering pixel point sets to which the combined segment numbers belong as a same connected domain, and carrying out color grade classification and numbering on the connected domain; and recording connected domain numbers where the pixel point is located in the pixel point data. According to the method and device, images can be segmented according to color blocks and color block connected domains, so that requirements of image analysis can be satisfied more widely.

The invention discloses a system for judging age and health status and identifying malignant arrhythmia by a pulse signal time-space domain combination model. The system comprises the following steps:acquiring pulse signals at a vessel part of the body surface of a human body for a preset time length; performing pulse signal time-space resolution modeling; and performing malignant arrhythmia identification and outbreak prediction based on the parameters of the pulse time-space analytical model. The invention proposes use of the pulse time-space analytical model to quantitatively describe pulse signal periods and waveform change, can judge age and rhythm of the heart, and can realize intelligent identification of malignant arrhythmia and outbreak early warning.

A receiving method of up - link in array antenna MC - CDMA system includes carrying out subcarrier separation to signal received by each array element in array antenna , carrying out despreading and matching filter treatment for each separated subcarrier signal for obtaining matched filter wave output of user , carrying out space domain combination for the same subcarrier belonging to the same user to obtain its subset gain , carrying out frequency domain combination to obtain its subset gain , deciding final decision variable of user signal for obtaining user decision result.

The invention discloses a moving object observation and fuzzy restoration method which comprises the following steps: a plurality of cameras of the same model that have a continuous shooting function are used for capturing photographs of moving objects in the same view field in a fixed manner, observation images are obtained; the obtained observation images are respectively subjected to moving fuzzy function estimation and segmentation extraction operation, and corresponding moving fuzzy object images are obtained; the obtained moving fuzzy object images and moving fuzzy functions are used, and clear object images can be obtained via a space domain combination restoration algorithm. The moving object observation and fuzzy restoration method has low requirements for hardware equipment, and only a plurality of digital cameras, popular in markets, that have a continuous capture function are required for solving a problem of high speed moving object observation and fuzzy restoration.

The invention provides a physical uplink shared channel transmission method and device, a terminal and a base station, and the method comprises the steps: receiving a physical downlink control channel(PDCCH) transmitted by using a preset downlink control information (DCI) format; and determining whether a physical uplink shared channel (PUSCH) corresponding to the PDCCH contains data or not at least according to indication information in a new data indication (NDI) indication domain and a modulation and coding strategy (MCS) indication domain in a DCI format used by the PDCCH. According to the scheme, multiple indication domain combinations in existing DCI are reused for judgment, and meanwhile it is judged that the PUSCH does not contain UL-. When the SCH corresponds to the TB, the modulation order of the UCI on the PUSCH can be further determined according to the MCS indication domain, and normal transmission of the PUSCH only bearing the UCI is achieved on the basis that the DCI indication overhead is not increased; the problem that in the prior art, whether a PUSCH contains UL-or not cannot be determined is well solved. And the SCH causes that the PUSCH cannot transmit normally.

The invention relates to an uplink receiving method of array antenna MC-DS-CDMA system. The method is carried out with the steps that: first, the signals received by each array unit of the array antenna are respectively transmitted to carrier signal separation modules and are multiplied with a corresponded sub-carrier, which realizes the sub-carrier signal separation and obtains an output signal; second, de-spread and matched filter process to each separated array unit sub-carrier signal are carried out to realize user signal de-spreading and get the user sub-carrier signal matched filter output; third, the matched filter output signals on different array units are combined in the air domain to get user sub-carrier signal final judge variable and get the air domain diversity gain; fourth, user sub-carrier signal final judge variable after air domain combination is judged to get the user sub-carrier signal judge result. The method obviously enhances MC-DS-CDMA system performance.

The invention provides a method for estimating parameters of a space stretching electromagnetic vector sensor array. The method comprises the steps of receiving K unrelated incoming signals through a receiving array, and constructing guide vectors of the incoming signals corresponding to the array; expressing the guide vectors of the incoming signals as a product of a spatial domain function array and a polarizational domain function vector; computing a covariance matrix of the received data; analyzing features of the covariance matrix of the received data to obtain signal subspace and noise subspace; constructing a multi-signal classified MUSIC spatial-polarizational domain combination zero spectrum function, and maximizing the spatial-polarizational domain combination zero spectrum function; performing MUSIC dimension reduction process to separate a spatial domain spectrum and a polarizational domain spectrum by means of the self-conjugate moment Rayleigh-Ritz entropy theorem, performing traversal search within value ranges of variables and estimating signal parameters. By means of the method, four-dimensional MUSIC search is transformed into two-dimensional spatial domain search and two-dimensional polarizational domain search, and therefore, calculated quantity is decreased.

Methods of treating cancer comprising administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and / or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are provided. Dosage packs comprising an FGFR1 ECD and / or an FGFR1 ECD fusion molecule and / or at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are also provided. In some embodiments, a dosage pack comprises instructions for administering FGFR1 ECD and / or FGFR1 ECD fusion molecule with at least one additional therapeutic agent.

The present invention relates to novel antibody variable domain combinations with advantageous properties.

The invention discloses an image processing method for triode counting, and the method comprises the steps: extracting a triode image shot by X rays, and obtaining an original image; performing firstglobal threshold segmentation in the original image of the image processing method for triode counting according to the fixed threshold to obtain a first image; performing first connected domain combination on the first image of the image processing method for triode counting to obtain a second image, and preprocessing the second image of the image processing method for triode counting to obtain athird image; performing automatic threshold on the third image of the image processing method for triode counting to obtain a triode region. According to the image processing method for triode counting, feature extraction and region number statistics are carried out on triode regions to obtain the number N of triodes, the defect that traditional packaging counting consumes manpower and time can be overcome, and the purposes of fast counting time and high accuracy are achieved.

Disclosed are a system and a method for statistically predicting an interaction probability between proteins, and more particularly to a system and a method for predicting an interaction probability between an unknown protein pair based on information obtained by analyzing differences between interacting and non-interacting sets of protein pairs from the view point of domain combination. The prediction method includes the steps of (a) obtaining appearance frequency information of a designated domain combination selected from each of interacting and non-interacting sets of protein pairs, and storing the obtained appearance frequency information, (b) determining a probability equation applied to predict the interaction between two proteins using the stored appearance frequency information of the domain combination, and (c) obtaining an interaction probability value between the two proteins from the determined probability equation.

The invention discloses a moving target observation and blur restoration method. The method uses multiple cameras of the same model with continuous shooting functions to capture and shoot moving targets in the same field of view to obtain observation images; the obtained observation images are separately processed. Motion blur function estimation and segmentation extraction are used to obtain respective motion blur target images; using the obtained motion blur target image and motion blur function, a spatial domain joint restoration algorithm is used to obtain a clear target image. The present invention has low requirements for hardware equipment and only requires a plurality of popular digital cameras with continuous shooting functions to solve the problems of high-speed moving target observation and blur restoration.

The invention discloses an image processing method for diode counting, and the method at least comprises the following steps: extracting a diode image shot by X rays, and obtaining a to-be-processed image; performing first global threshold segmentation in the to-be-processed image according to the fixed threshold to obtain a first image; performing first connected domain combination on the first image to obtain a second image, and preprocessing the second image to obtain a third image; performing feature extraction on the third image to obtain a diode region image; performing global thresholdsegmentation and region number statistics on the diode region image to obtain the number N of diodes; wherein N is a positive integer greater than or equal to 1. According to the image processing method for diode counting provided by the invention, the defect that the traditional packaging counting consumes manpower and time can be solved, and the purposes of fast counting time and high precisionare achieved.

Methods of treating cancer comprising administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and / or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are provided. Dosage packs comprising an FGFR1 ECD and / or an FGFR1 ECD fusion molecule and / or at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are also provided. In some embodiments, a dosage pack comprises instructions for administering FGFR1 ECD and / or FGFR1 ECD fusion molecule with at least one additional therapeutic agent.

The invention provides a channel and observation domain combination multi-path restraining method in a GPS receiver, and belongs to the technical field of satellite navigation. The channel and observation domain combination multi-path restraining method includes the steps of firstly, expanding channel correlator branches of a standard receiver, improving the delay resolution ratio, extending a delay coverage range, then using a multi-path channel to output the characteristics causing distortion of a correlation function, building a multi-path balancer in a receiver channel, estimating multi-path signal components, compensating a multi-path tracking error, and finally using the wavelet-threshold-based filtering algorithm to build a multi-path filter for the receiver observed quantity to restrain the multi-path error in the pseudo-range and carrier phase observed quantity. The channel and observation domain combination multi-path restraining method does not depend on the assumption related to multi-path parameter prior probability distribution to be estimated and can be well suitable for dynamic changes of the multi-path environment, and the multi-path errors in GPS receiver codes, a carrier wave tracking loop and the pseudo-range and carrier phase observed quantity are eliminated through the multi-path processing comprehensive method.

The present invention relates to novel antibody variable domain combinations with advantageous properties.

Generating a contributor-based power abstract for a device, including: identifying a clock power component for each of a plurality of clock gating domains, identifying a switching characteristic for each of the clock gating domains, combining the switching characteristics for all of the clock gating domains into a domain combination list, performing a per-case simulation based at least on the domain combination list, calculating an effective capacitance for each of the clock gating domains based at least on the per-case simulation, and generating a power abstract for each of the clock gating domains based at least on the effective capacitance.

Generating a contributor-based power abstract for a device, including: identifying a clock power component for each of a plurality of clock gating domains, identifying a switching characteristic for each of the clock gating domains, combining the switching characteristics for all of the clock gating domains into a domain combination list, performing a per-case simulation based at least on the domain combination list, calculating an effective capacitance for each of the clock gating domains based at least on the per-case simulation, and generating a power abstract for each of the clock gating domains based at least on the effective capacitance.

The invention relates to an uplink receiving method of array antenna MC-DS-CDMA system. The method is carried out with the steps that: first, the signals received by each array unit of the array antenna are respectively transmitted to carrier signal separation modules and are multiplied with a corresponded sub-carrier, which realizes the sub-carrier signal separation and obtains an output signal;second, de-spread and matched filter process to each separated array unit sub-carrier signal are carried out to realize user signal de-spreading and get the user sub-carrier signal matched filter output; third, the matched filter output signals on different array units are combined in the air domain to get user sub-carrier signal final judge variable and get the air domain diversity gain; fourth,user sub-carrier signal final judge variable after air domain combination is judged to get the user sub-carrier signal judge result. The method obviously enhances MC-DS-CDMA system performance.

The invention belongs to the technical field of HEVC (High Efficiency Video Coding), and discloses a code rate control method based on a subjective region of interest and time-space domain combination. The method comprises the following steps: calculating each CTU grade target bit allocation weight based on a space domain; calculating a motion region of each frame of image based on light streams and a global motion estimation algorithm to serve as a time domain region of interest; adjusting the obtained CTU grade target bit allocation weights according to a time domain region of interest result obtained on the basis of the light streams and the global motion estimation algorithm; performing a center enhancing operation on the CTU grade target bit allocation weights obtained through time-space domain subjective region of interest detection; obtaining final coding CTU grade target bit allocation to perform a coding operation; and modifying a video compression final evaluation standard. Compared with an HM16.0 compression model, the code rate control method has the advantages that the HEVC compression subjective effect is enhanced under the condition of ensuring that a target bit code rate is invariable.

The invention discloses a method for reporting scheduling information. The method comprises the following steps: a terminal reports the scheduling information to the base station, wherein in the indication mode of combining domain combination values in scheduling information, the scheduling information indicates that in the scheduling information, the current terminal power clear space is the terminal power clear space corresponding to one of the two carriers. The invention also discloses a system for reporting scheduling information. A reporting unit in the system at the terminal side is used for reporting the scheduling information to the base station, wherein in the indication mode of combining domain combination values in scheduling information, the scheduling information indicates that in the scheduling information, the current terminal power clear space is the terminal power clear space corresponding to one of the two carriers. The method and system can be used for reporting scheduling information; and the scheduling information can clearly indicate that the terminal power clear space domain in the scheduling information aims at the terminal power clear space of one of the two carriers, thereby facilitating the pertinent analysis of the base station and scheduling the resources in a better way.

The invention discloses a multi-color grade image connected domain-based segmentation and mark method and device. The method comprises the following steps of: preprocessing an image to ensure that image color lumps of two or more color grades are divided from the image; obtaining pixel point data of the image color block of each color grade; respectively finding out a connection line formed by pixel points which are continuously connected in at least two preset directions according to the pixel point data so as to obtain a sub-segments, and marking numbers for the sub-segments; recording segment numbers of one or more sub-segments where the pixel points are located in the pixel point data; combining the segment numbers according to a preset connected domain combination rule, considering pixel point sets to which the combined segment numbers belong as a same connected domain, and carrying out color grade classification and numbering on the connected domain; and recording connected domain numbers where the pixel point is located in the pixel point data. According to the method and device, images can be segmented according to color blocks and color block connected domains, so that requirements of image analysis can be satisfied more widely.

A receiving method of up - link in array antenna MC - CDMA system includes carrying out subcarrier separation to signal received by each array element in array antenna , carrying out despreading and matching filter treatment for each separated subcarrier signal for obtaining matched filter wave output of user , carrying out space domain combination for the same subcarrier belonging to the same user to obtain its subset gain , carrying out frequency domain combination to obtain its subset gain , deciding final decision variable of user signal for obtaining user decision result.

The present invention relates to a processing method and device for image classification, and an image retrieval method, device and system, wherein the method for processing image classification includes the following steps: performing preprocessing on each sample image to obtain the relationship between each sample image and known information The association relationship of the image to be processed is performed on the color block segmentation process to obtain the segmented color block image of the image to be processed; the pixel point groups with interconnected relationships in the segmented color block image are marked and re-segmented to obtain the segmented color block image Each connected domain diagram of the color block image; based on the association relationship between each sample image and known information, the connected domain diagrams are combined according to the preset connected domain combination rules to obtain each connected domain combination diagram; the connected domain combination diagram and other connected domain graphs that cannot be combined are confirmed as sub-card images of the image to be processed. The invention can overcome the problem of missed detection of approximate images with partial features in multi-feature image retrieval.